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3 results for "DNA-PKcs Small Molecules and Peptides" in Products

DNA-PKcs: Small Molecules and Peptides

DNA-PKcs (DNA-dependent protein kinase catalytic subunit) is a member of the PI 3-kinase related kinase (PIKK) superfamily. DNA-PKcs is a serine/threonine kinase that, along with the DNA-binding proteins Ku70/Ku80, binds to regions of DNA double strand breaks, and is involved in double-strand break repair and VDJ recombination.

Potent and selective DNA-PK inhibitor

Alternate Names: KU 57788
Chemical Name: 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one
Purity: ≥98% (HPLC)
Potent and selective DNA-PK inhibitor

Potent and selective DNA-PK inhibitor; enhances CRISPR-mediated HDR efficiency

Chemical Name: 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one
Purity: ≥98% (HPLC)
Potent and selective DNA-PK inhibitor

Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK

Alternate Names: GSK2126458
Chemical Name: 2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide
Purity: ≥98% (HPLC)
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
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