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DNA-PKcs Products
DNA-PKcs (DNA-dependent protein kinase catalytic subunit) is a member of the PI 3-kinase related kinase (PIKK) superfamily. DNA-PKcs is a serine/threonine kinase that, along with the DNA-binding proteins Ku70/Ku80, binds to regions of DNA double strand breaks, and is involved in double-strand break repair and VDJ recombination.
8 results for "DNA-PKcs" in Products
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DNA-PKcs Products
DNA-PKcs (DNA-dependent protein kinase catalytic subunit) is a member of the PI 3-kinase related kinase (PIKK) superfamily. DNA-PKcs is a serine/threonine kinase that, along with the DNA-binding proteins Ku70/Ku80, binds to regions of DNA double strand breaks, and is involved in double-strand break repair and VDJ recombination.
8 results for "DNA-PKcs" in Products
Potent and selective DNA-PK inhibitor
| Alternate Names : | KU 57788 |
| Chemical Name : | 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one |
| Purity : | ≥99% (HPLC) |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
Selective DNA-PK inhibitor
| Chemical Name : | 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one |
| Purity : | ≥98% (HPLC) |
Dual DNA-PK and PI 3-K inhibitor
| Chemical Name : | 4-Ethyl-N-[4-[2-(4-morpholinyl)-4-oxo-4H-1-benzopyran-8-yl]-1-dibenzothienyl]-1-piperazineacetamide |
| Purity : | ≥97% (HPLC) |
Potent and selective DNA-PK inhibitor
| Chemical Name : | 7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one |
| Purity : | ≥98% (HPLC) |
Inhibitor of PI 3-kinase, mTOR and DNA-PK
| Chemical Name : | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Purity : | ≥98% (HPLC) |
Highly potent PI 3-kinase inhibitor; also potent inhibitor of mTOR and DNA-PK
| Alternate Names : | GSK2126458 |
| Chemical Name : | 2,4-Difluoro-N-[2-methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide |
| Purity : | ≥98% (HPLC) |
Dual kinase inhibitor; inhibits PI 3-K family kinases
| Chemical Name : | 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity : | ≥98% (HPLC) |
