Sign In / Register
Dkk-3 Products
Dkk-3, also known as REIC, is a member of the Dickkopf family of secreted Wnt antagonists. Dkk-3 is expressed most strongly in adult heart, brain, and spinal cord as well as during early embryonic development. Dkk-3 is downregulated in many tumors which often is correlated with faster tumor progression and shorter survival. The prototype Dickkopf member, Dkk-1, antagonizes Wnt family signaling by binding to Wnt receptors LRP5 and LRP6 (low-density lipoprotein receptor-related proteins) and promoting their internalization. In contrast, Dkk-3 may either promote or inhibit Wnt signaling.
9 results for "Dkk-3" in Products
Search
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
Dkk-3 Products
Dkk-3, also known as REIC, is a member of the Dickkopf family of secreted Wnt antagonists. Dkk-3 is expressed most strongly in adult heart, brain, and spinal cord as well as during early embryonic development. Dkk-3 is downregulated in many tumors which often is correlated with faster tumor progression and shorter survival. The prototype Dickkopf member, Dkk-1, antagonizes Wnt family signaling by binding to Wnt receptors LRP5 and LRP6 (low-density lipoprotein receptor-related proteins) and promoting their internalization. In contrast, Dkk-3 may either promote or inhibit Wnt signaling.
9 results for "Dkk-3" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Source : | NS0 |
| Accession # : | Q9UBP4.1 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunohistochemistry, Western Blot |
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #138728 |
| Applications : | ELISA Capture |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #138726 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #153103 |
| Applications : | Western Blot |
