4 results for "Diacylglycerol O-Acyltransferase (DGAT) Inhibitors Small Molecules and Peptides" in Products
Diacylglycerol O-Acyltransferase (DGAT) Inhibitors: Small Molecules and Peptides
Diacylglycerol O-Acyltransferases (DGATs), EC 2.3.1.20, are enzymes that catalyze the final step of triglyceride (TG) synthesis, the covalent attachment of fatty acyl-CoA and diacylglycerol (DAG). There have been two DGAT isoforms identified to date, DGAT1 and DGAT2, which are members of the MBOAT and DAGAT families of acyltransferases, respectively.
DGAT1/2 have a wide expression profile, being highly expressed in adipocytes, hepatocytes, enterocytes and the mammary gland, and are typically ...
| Chemical Name: | [(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinylmethanone methanesulfonate |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | trans-4-[-[[[5-[(3,4-Difluorophenyl)amino]-1,3,4-oxadiazol-2-yl]carbonyl]amino]phenyl]cyclohexaneacetic acid |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]cyclohexaneacetic acid |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 3-Bromo-4-[2-fluoro-4-[[4-oxo-2-[[2-(pyridin-2-yl)ethyl]amino]-1,3-thiazol-5-(4H)ylidene]methyl]phenoxy]benzonitrile |
