
CXCR4: Antibodies
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.
67 results for "CXCR4 Primary Antibodies" in Products
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Conjugates
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CXCR4: Antibodies
CXCR4, also known as fusin or LESTR, is a G protein-coupled receptor (GPCR) member of the CXC subfamily of chemokine receptors. Human CXCR4 is 352 amino acids (aa) in length with a predicted molecular weight of 40 kDa. The mouse and rat proteins share 91% aa sequence identity with the human protein. CXCR4 is the chemokine receptor for CXCL12. CXCR4 is a critical regulator of progenitor and stem cell mobilization and recruitment during development and during hematopoiesis. As such, antagonists of CXCR4 can be used to harvest hematopoietic stem/progenitor cells from bone marrow. Significantly, CXCR4 also acts as a co-receptor for HIV and mediates viral entry and infection of T cells. Studies on multiple tumor types implicate the CXCL12:CXCR4 axis in tumor metastasis and angiogenesis.
67 results for "CXCR4 Primary Antibodies" in Products
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5R |
Applications : | Block/Neutralize, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #44716 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #44717 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #247506 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Block/Neutralize, CyTOF-reported, Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #44717 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #44717 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #374606 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #247506R |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #44708 |
Applications : | Block/Neutralize |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5R |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5R |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #44717 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #374606 |
Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #44717 |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #247506R |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #247506 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2b Clone #247506 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #12G5 |
Applications : | Flow Cytometry |