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CXCL5/ENA-78 Products
CXCL5/Epithelial Cell-derived Neutrophil-activating Peptide (ENA-78), is a member of the CXC subfamily of chemokines. Full-length CXCL5/ENA-78 is 114 amino acids (aa) in length with a predicted molecular weight of 12 kDa. Following the removal of the signal peptide, bioactive CXCL5/ENA-78 is 78 aa in length. CXCL5/ENA-78 can be N-terminally cleaved by Cathepsin G and Chymotrypsin to CXCL5/ENA-74 (74 aa) and CXCL5/ENA-70 (70 aa), which show increased potency relative to CXCL5/ENA-78. While murine LIX was thought to be an ortholog to human CXCL5/ENA-78, genome-wide analysis and a consensus in the field suggests that human CXCL5/ENA-78 does not have a true murine ortholog. CXCL5/ENA-78 is upregulated at sites of inflammation and is expressed by multiple hematopoietic cell types, fibroblasts, endothelial cells, vascular smooth muscle cells, and adipocytes. It acts as a chemoattractant for neutrophils, has angiogenic properties, and contributes to cancer progression.
24 results for "CXCL5/ENA-78" in Products
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CXCL5/ENA-78 Products
CXCL5/Epithelial Cell-derived Neutrophil-activating Peptide (ENA-78), is a member of the CXC subfamily of chemokines. Full-length CXCL5/ENA-78 is 114 amino acids (aa) in length with a predicted molecular weight of 12 kDa. Following the removal of the signal peptide, bioactive CXCL5/ENA-78 is 78 aa in length. CXCL5/ENA-78 can be N-terminally cleaved by Cathepsin G and Chymotrypsin to CXCL5/ENA-74 (74 aa) and CXCL5/ENA-70 (70 aa), which show increased potency relative to CXCL5/ENA-78. While murine LIX was thought to be an ortholog to human CXCL5/ENA-78, genome-wide analysis and a consensus in the field suggests that human CXCL5/ENA-78 does not have a true murine ortholog. CXCL5/ENA-78 is upregulated at sites of inflammation and is expressed by multiple hematopoietic cell types, fibroblasts, endothelial cells, vascular smooth muscle cells, and adipocytes. It acts as a chemoattractant for neutrophils, has angiogenic properties, and contributes to cancer progression.
24 results for "CXCL5/ENA-78" in Products
Catalog #:
SPCK-PANEL
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Luminex Discovery Assays provide the most flexible assays on the market. These panels are completely customizable using our large menu of human, mouse, and rat analytes, making them the perfect tool for biomarker discovery and screening.
Build your own Luminex Assay with our Luminex Assay Customization Tool.
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
ELISA
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies
ELISA
| Assay Range : | 15.6 - 1,000 pg/mL |
| Applications : | ELISA |
ELISA
| Sensitivity : | 15 pg/mL |
| Assay Range : | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Heparin Plasma, Citrate Plasma) |
| Applications : | ELISA |
BA
| Source : | E. coli |
| Accession # : | P42830 |
| Applications : | Bioactivity |
Catalog #:
IC654S
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
Catalog #:
IC654R
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
CyTOF-ready, ICFlow, Neut
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Block/Neutralize, CyTOF-ready, ELISA Capture, Flow Cytometry |
WB, IHC, Neut
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33160 |
| Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
Catalog #:
SPCKB-PS-000334
Simple Plex Cartridge Kit containing ENA-78 for use with Human CCS/Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.
Catalog #:
MAB2541
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33103 |
| Applications : | Western Blot |
Catalog #:
BAF254
WB
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Western Blot |
WB, IHC, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
Catalog #:
AB-254-PB
WB, Neut
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
Catalog #:
IC654T
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Sensitivity : | 4.14 pg/mL |
| Assay Range : | 9 - 6,900 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Catalog #:
IC654V
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
Catalog #:
IC654U
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
Catalog #:
IC654G
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
Catalog #:
IC654N
ICFlow
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #33170 |
| Applications : | Flow Cytometry |
