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CXCL5/ENA-78 Products

CXCL5/Epithelial Cell-derived Neutrophil-activating Peptide (ENA-78), is a member of the CXC subfamily of chemokines. Full-length CXCL5/ENA-78 is 114 amino acids (aa) in length with a predicted molecular weight of 12 kDa. Following the removal of the signal peptide, bioactive CXCL5/ENA-78 is 78 aa in length. CXCL5/ENA-78 can be N-terminally cleaved by Cathepsin G and Chymotrypsin to CXCL5/ENA-74 (74 aa) and CXCL5/ENA-70 (70 aa), which show increased potency relative to CXCL5/ENA-78. While murine LIX was thought to be an ortholog to human CXCL5/ENA-78, genome-wide analysis and a consensus in the field suggests that human CXCL5/ENA-78 does not have a true murine ortholog. CXCL5/ENA-78 is upregulated at sites of inflammation and is expressed by multiple hematopoietic cell types, fibroblasts, endothelial cells, vascular smooth muscle cells, and adipocytes. It acts as a chemoattractant for neutrophils, has angiogenic properties, and contributes to cancer progression.

24 results for "CXCL5/ENA-78" in Products

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CXCL5/ENA-78 Products

CXCL5/Epithelial Cell-derived Neutrophil-activating Peptide (ENA-78), is a member of the CXC subfamily of chemokines. Full-length CXCL5/ENA-78 is 114 amino acids (aa) in length with a predicted molecular weight of 12 kDa. Following the removal of the signal peptide, bioactive CXCL5/ENA-78 is 78 aa in length. CXCL5/ENA-78 can be N-terminally cleaved by Cathepsin G and Chymotrypsin to CXCL5/ENA-74 (74 aa) and CXCL5/ENA-70 (70 aa), which show increased potency relative to CXCL5/ENA-78. While murine LIX was thought to be an ortholog to human CXCL5/ENA-78, genome-wide analysis and a consensus in the field suggests that human CXCL5/ENA-78 does not have a true murine ortholog. CXCL5/ENA-78 is upregulated at sites of inflammation and is expressed by multiple hematopoietic cell types, fibroblasts, endothelial cells, vascular smooth muscle cells, and adipocytes. It acts as a chemoattractant for neutrophils, has angiogenic properties, and contributes to cancer progression.

24 results for "CXCL5/ENA-78" in Products

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 31 different chemokine antibodies

Catalog #: IC654S
ICFlow
ICFlow
CyTOF-ready, ICFlow, Neut
WB, IHC, Neut

Simple Plex Cartridge Kit containing ENA-78 for use with Human CCS/Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

WB
WB
WB, IHC, Neut
WB, Neut
Catalog #: IC654T
ICFlow
Catalog #: IC654V
ICFlow
Catalog #: IC654U
ICFlow
Catalog #: IC654G
ICFlow
Catalog #: IC654N
ICFlow
Catalog #: 898253

Control for use with Human CXCL5/ENA-78 Simple Plex Cartridge Kit

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