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119 results for "CTLA-4 Antibodies" in Products

CTLA-4 Antibodies

CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.

Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Detection of Human CTLA-4 antibody by Western Blot.
(5)
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #63828
Applications:
WB, B/N, Flow, CyTOF-ready
CTLA‑4 Inhibition of B7‑1/CD80-induced IL‑2 Secretion and Neutralization by Mouse CTLA‑4 Antibody.

Recombinant Monoclonal Antibody For Research Use Only

Reactivity:
Human
Details:
Human IgG1 Monoclonal Clone #Hu111
Applications:
Flow, CyTOF-ready
Detection of CTLA-4 antibody in HEK293 Human cell line Transfected with Human CTLA-4 and eGFP antibody by Flow Cytometry.
(2)

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Detection of CTLA-4 antibody in NS0 Mouse Cell Line Transfected with Human CTLA-4 and eGFP antibody by Flow Cytometry.
(2)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #2188B
Applications:
Flow, ICC/IF, CyTOF-ready
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #63828
Applications:
WB, B/N, Flow, CyTOF-ready
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