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CRHR1 Products

CRHR1, also known as CHR-R1 and Corticotropin Releasing Factor Receptor 1, CRF 1, is a member of the Class B G protein-coupled receptor family that mediates the action of hypothalamic and peripheral CRH. It is the key regulator of the stress response in the hypothalamic-pituitary adrenal axis and an important functional mediator of the endocrine, cardiovascular, gastrointestinal, and immune systems. The other major endogenous ligand for CRHR1 is Urocortin 1.

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51 results for "CRHR1" in Products

51 results for "CRHR1" in Products

CRHR1 Products

CRHR1, also known as CHR-R1 and Corticotropin Releasing Factor Receptor 1, CRF 1, is a member of the Class B G protein-coupled receptor family that mediates the action of hypothalamic and peripheral CRH. It is the key regulator of the stress response in the hypothalamic-pituitary adrenal axis and an important functional mediator of the endocrine, cardiovascular, gastrointestinal, and immune systems. The other major endogenous ligand for CRHR1 is Urocortin 1.

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High affinity CRF1 antagonist; orally bioavailable

Potent and selective CRF1 antagonist; anxiolytic

CRF1 agonist

Potent and selective CRF1 antagonist; binds at an allosteric site

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