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171 results for "cIAP-1/HIAP-2" in Products

cIAP-1/HIAP-2 Products

Cellular inhibitor of apoptosis protein1 (cIAP-1, also known as BIRC2, MIHB, and HIAP2) and 2 (cIAP-2, also known as BIRC3, MIHC, and HIAP1), are members of the inhibitor of apoptosis (IAP) family of proteins that inhibit the proteolytic activity of mature caspases. Structurally, cIAP-1 and cIAP-2 are each comprised of 3 BIR (baculovirus inhibitor of apoptosis) domains, a RING finger domain, and a caspase recruitment domain (CARD). Human cIAP-1 and cIAP-2 share 70% sequence identity. ...

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Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies

Determination of Relative Levels of Human Apoptosis-related Proteins Using Proteome Profiler Human Apoptosis Array Kit.
(2)

Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies

Detection of human NFkB Pathway proteins in HCT-116 cells.
(3)

Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins

R&D Systems Proteome Profiler Antibody Array Kits
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #681732
Source: E. coli
Accession #: Q13490
Applications: InhibAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #681724
Reactivity: Human
Details: Goat IgG Polyclonal
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #681732

Monovalent IAP antagonist

Chemical Name: (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-phenoxy-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide
Purity: ≥97% (HPLC)
Selective cIAP1 Degrader (PROTAC®)

Potent Lys-covalent pan-IAP inhibitor

Chemical Name: (R)-1-((S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-2,3-dihydro-1H-inden-4-yl sulfurofluoridate
Purity: ≥95% (HPLC)
Potent Lys-covalent pan-IAP antagonist
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