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4 results for "CDK8 Small Molecules and Peptides" in Products
CDK8 Small Molecules and Peptides
Cdk8 is encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. ...
Cdk inhibitor; potently inhibits cdk2 and cdk9
Alternate Names:
L 86-8275
Chemical Name:
2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride
Purity:
≥98%
Cdk8 inhibitor
Chemical Name:
4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride
Purity:
≥98%
CDK8 Degrader (PROTAC®)
Chemical Name:
15-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-N-[(3β,5α,17β)-17-(7-isoquinolinyl)androstan-3-yl]-N-methyl-4,7,10,13-tetraoxapentadecanamide
Purity:
≥98%
Cdk inhibitor; potently inhibits cdk2 and cdk9
Alternate Names:
L 86-8275
Chemical Name:
2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride
Purity:
≥98%