CD163 Products
CD163, also known as M130 and p155, is a transmembrane scavenger receptor that is expressed on monocytes and macrophages and is inducible by immunosuppressant glucocorticoids and IL-10. A soluble form is shed from the cell surface by TACE or neutrophil elastase mediated cleavage in response to oxidative stress, Prostaglandin F2a stimulation, or the activation of Fc gamma receptors, TLR1, 2, 5, or 6. CD163 mediates monocyte binding to bacteria, leading to the release of inflammatory cytokines. It is essential for the circulatory clearance of hemoglobin-haptoglobin (Hb-Hp) complexes as well as free hemoglobin. It can also mediate monocyte-erythroblast adhesion and promote erythroblast expansion. CD163 binds and internalizes the cytokine TWEAK, and the ratio of soluble CD163 to TWEAK in the plasma is elevated during atherosclerosis.
617 results for "CD163" in Products
617 results for "CD163" in Products
CD163 Products
CD163, also known as M130 and p155, is a transmembrane scavenger receptor that is expressed on monocytes and macrophages and is inducible by immunosuppressant glucocorticoids and IL-10. A soluble form is shed from the cell surface by TACE or neutrophil elastase mediated cleavage in response to oxidative stress, Prostaglandin F2a stimulation, or the activation of Fc gamma receptors, TLR1, 2, 5, or 6. CD163 mediates monocyte binding to bacteria, leading to the release of inflammatory cytokines. It is essential for the circulatory clearance of hemoglobin-haptoglobin (Hb-Hp) complexes as well as free hemoglobin. It can also mediate monocyte-erythroblast adhesion and promote erythroblast expansion. CD163 binds and internalizes the cytokine TWEAK, and the ratio of soluble CD163 to TWEAK in the plasma is elevated during atherosclerosis.
| Sensitivity: | 0.613 ng/mL |
| Applications: | ELISA |
| Assay Range: | 1.56 - 100 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma) |
| Reactivity: | Human, Bovine, Porcine, Primate - Macaca mulatta (Rhesus Macaque), Primate - Macaca leonina (Northern Pig-Tailed Macaque) |
| Details: | Mouse IgG1 Monoclonal Clone #EDHu-1 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +2 More |
| Assay Range: | 156 - 10,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC |
Control for use with Human CD163 2nd Gen and Non-Human Primate CD163 Simple Plex Assay Cartridge Kit
| Applications: | Ctrl, Simple Plex |
Simple Plex Human CD163 2nd Gen assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #10D6 |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: CD163 Antibody (10D6) [NB110-59935]](https://resources.bio-techne.com/images/products/CD163-Antibody-10D6-Immunohistochemistry-Paraffin-NB110-59935-img0003.jpg "Immunohistochemistry-Paraffin: CD163 Antibody (10D6) [NB110-59935]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #215927 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #215927 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #6D3.2F3 |
| Applications: | IHC, WB, Flow |
![Western Blot: CD163 Antibody (6D3.2F3)BSA Free [NBP2-36495]](https://resources.bio-techne.com/images/products/CD163-Antibody-6D3-2F3-Western-Blot-NBP2-36495-img0001.jpg "Western Blot: CD163 Antibody (6D3.2F3)BSA Free [NBP2-36495]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #215927 |
| Applications: | Flow |
Simple Plex Non-Human Primate CD163 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #ED2 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Immunocytochemistry/ Immunofluorescence: CD163 Antibody (ED2) - BSA Free [NBP2-39099]](https://resources.bio-techne.com/images/products/CD163-Antibody-ED2-Immunocytochemistry-Immunofluorescence-NBP2-39099-img0013.jpg "Immunocytochemistry/ Immunofluorescence: CD163 Antibody (ED2) - BSA Free [NBP2-39099]")
| Assay Range: | 0.312 - 20 ng/mL |
| Applications: | ELISA |
For use with catalog number DC1630
| Applications: | Ctrl |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #215930 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5C6-FAT |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
| Source: | NS0 |
| Accession #: | CAA80543 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | AAK16065 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #1084111 |
| Applications: | Flow, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #215927 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #215927 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #R20 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #612722 |
| Applications: | WB, ICC |
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #RM3/1 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Immunohistochemistry-Frozen: CD163 Antibody (RM3/1) [NBP1-60158]](https://resources.bio-techne.com/images/products/CD163-Antibody-RM3-1-Immunohistochemistry-Frozen-NBP1-60158-img0001.jpg "Immunohistochemistry-Frozen: CD163 Antibody (RM3/1) [NBP1-60158]")