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CD163 Products

CD163, also known as M130 and  p155, is a transmembrane scavenger receptor that is expressed on monocytes and macrophages and is inducible by immunosuppressant glucocorticoids and IL-10. A soluble form is shed from the cell surface by TACE or neutrophil elastase mediated cleavage in response to oxidative stress, Prostaglandin F2a stimulation, or the activation of Fc gamma receptors, TLR1, 2, 5, or 6. CD163 mediates monocyte binding to bacteria, leading to the release of inflammatory cytokines. It is essential for the circulatory clearance of hemoglobin-haptoglobin (Hb-Hp) complexes as well as free hemoglobin. It can also mediate monocyte-erythroblast adhesion and promote erythroblast expansion. CD163 binds and internalizes the cytokine TWEAK, and the ratio of soluble CD163 to TWEAK in the plasma is elevated during atherosclerosis.

33 results for "CD163" in Products

CD163 Products

CD163, also known as M130 and  p155, is a transmembrane scavenger receptor that is expressed on monocytes and macrophages and is inducible by immunosuppressant glucocorticoids and IL-10. A soluble form is shed from the cell surface by TACE or neutrophil elastase mediated cleavage in response to oxidative stress, Prostaglandin F2a stimulation, or the activation of Fc gamma receptors, TLR1, 2, 5, or 6. CD163 mediates monocyte binding to bacteria, leading to the release of inflammatory cytokines. It is essential for the circulatory clearance of hemoglobin-haptoglobin (Hb-Hp) complexes as well as free hemoglobin. It can also mediate monocyte-erythroblast adhesion and promote erythroblast expansion. CD163 binds and internalizes the cytokine TWEAK, and the ratio of soluble CD163 to TWEAK in the plasma is elevated during atherosclerosis.

33 results for "CD163" in Products

WB, Simple Western

Simple Plex Cartridge Kit containing CD163 for use with Human Plasma/Serum. Includes wash buffer and sample diluent. For use with the Ella automated immunoassay system.

Catalog #: QC61
Ctrl

For use with catalog number DC1630

WB, Flow, CyTOF-ready
Bind
Flow, CyTOF-ready
Catalog #: FAB16072R
Flow
Flow
BA
Catalog #: FAB1607R
Flow
Catalog #: BAM16072
Flow
Catalog #: FAB1607S
Flow
Catalog #: FAB16072N
Flow
Catalog #: FAB16072G
Flow
Catalog #: BAF1607
WB
Catalog #: FAB1607V
Flow
Catalog #: FAB1607U
Flow
Catalog #: FAB1607T
Flow
Catalog #: FAB16072U
Flow
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