CD161 Products
CD161, also known as KLRB1, NK1.1, and NKR-P1A is a 40 kDa type II transmembrane glycoprotein that contains one C-type lectin domain in its extracellular region. CD161 is expressed as a disulfide-linked dimer on the surface of Th17 cells and NK cells as well as on subsets of CD1-restricted T cells, intestinal NT cells, peripheral memory T cells, monocytes, and dendritic cells. It binds to OCIL/CLEC2d, leading to an inhibition of NK cell-mediated cytotoxicity and IFN-gamma secretion. Alternatively, CD161 can enhance TCR activation to CD1d ligation. CD161+ cell populations are depleted in ulcerative colitis, Grave's disease, and AIDS, although CD161+ T cells are activated during asthmatic attacks. Additional related proteins are expressed in mouse but not human: the inhibitory NKR-P1B and D, and the stimulatory NKR-P1A, C, and F.
262 results for "CD161" in Products
262 results for "CD161" in Products
CD161 Products
CD161, also known as KLRB1, NK1.1, and NKR-P1A is a 40 kDa type II transmembrane glycoprotein that contains one C-type lectin domain in its extracellular region. CD161 is expressed as a disulfide-linked dimer on the surface of Th17 cells and NK cells as well as on subsets of CD1-restricted T cells, intestinal NT cells, peripheral memory T cells, monocytes, and dendritic cells. It binds to OCIL/CLEC2d, leading to an inhibition of NK cell-mediated cytotoxicity and IFN-gamma secretion. Alternatively, CD161 can enhance TCR activation to CD1d ligation. CD161+ cell populations are depleted in ulcerative colitis, Grave's disease, and AIDS, although CD161+ T cells are activated during asthmatic attacks. Additional related proteins are expressed in mouse but not human: the inhibitory NKR-P1B and D, and the stimulatory NKR-P1A, C, and F.
| Source: | CHO |
| Accession #: | Q12918 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #14F1F11 |
| Applications: | IHC, WB |
![Western Blot: CD161 Antibody (14F1F11)Azide and BSA Free [NBP2-31359]](https://resources.bio-techne.com/images/products/CD161-Antibody-14F1F11-Azide-Free-Western-Blot-NBP2-31359-img0002.jpg "Western Blot: CD161 Antibody (14F1F11)Azide and BSA Free [NBP2-31359]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #14F1F11 |
| Applications: | IHC, WB |
![Western Blot: CD161 Antibody (14F1F11)BSA Free [NBP2-14845]](https://resources.bio-techne.com/images/products/CD161-Antibody-14F1F11-Western-Blot-NBP2-14845-img0006.jpg "Western Blot: CD161 Antibody (14F1F11)BSA Free [NBP2-14845]")
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | IHC, Flow, IP |
![Flow Cytometry: CD161 Antibody (10/78) - BSA Free [NB100-65297]](https://resources.bio-techne.com/images/products/CD161-Antibody-10-78-Flow-Cytometry-NB100-65297-img0001.jpg "Flow Cytometry: CD161 Antibody (10/78) - BSA Free [NB100-65297]")
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | IHC, Flow, IP, CyTOF-ready |
![Flow Cytometry: CD161 Antibody (10/78) - Azide and BSA Free [NBP2-80629]](https://resources.bio-techne.com/images/products/CD161-Antibody-10-78-Azide-and-BSA-Free-Flow-Cytometry-NBP2-80629-img0001.jpg "Flow Cytometry: CD161 Antibody (10/78) - Azide and BSA Free [NBP2-80629]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #B199.2 |
| Applications: | IHC, ICC/IF, Flow, IP, WB (-) |
![Flow Cytometry: CD161 Antibody (B199.2) - BSA Free [NB100-65298]](https://resources.bio-techne.com/images/products/CD161-Antibody-B199-2-Flow-Cytometry-NB100-65298-img0002.jpg "Flow Cytometry: CD161 Antibody (B199.2) - BSA Free [NB100-65298]")
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 kappa Monoclonal Clone #HP-3G10 |
| Applications: | IHC, WB, Flow |
![Flow Cytometry: CD161 Antibody (HP-3G10) - BSA Free [NBP3-09155]](https://resources.bio-techne.com/images/products/CD161-Antibody-HP-3G10-Flow-Cytometry-NBP3-09155-img0002.jpg "Flow Cytometry: CD161 Antibody (HP-3G10) - BSA Free [NBP3-09155]")
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #14F2F11 |
| Applications: | IHC, WB |
![Western Blot: CD161 Antibody (14F2F11) [NBP2-14844]](https://resources.bio-techne.com/images/products/CD161-Antibody-14F2F11-Western-Blot-NBP2-14844-img0002.jpg "Western Blot: CD161 Antibody (14F2F11) [NBP2-14844]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #14F2F11 |
| Applications: | WB |
![Western Blot: CD161 Antibody (14F2F11)Azide and BSA Free [NBP2-80630]](https://resources.bio-techne.com/images/products/CD161-Antibody-14F2F11-Azide-and-BSA-Free-Western-Blot-NBP2-80630-img0001.jpg "Western Blot: CD161 Antibody (14F2F11)Azide and BSA Free [NBP2-80630]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #702228 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #10/78 |
| Applications: | Flow |