171 results for "Caspase-9" in Products
Caspase-9 Products
Caspase-9, also known as APAF-3, Mch6 and ICE-LAP6, is a 35-37 kDa member of the peptidase C14A family of enzymes. Caspase-9 is an initiator caspase that is part of the intrinsic apoptosis pathway. It is widely expressed and is particularly important during development. Following mitochondrial disruption, Cytochrome c is released from mitochrondria and interacts with APAF-1, resulting in Pro-Caspase-9 dimerization. The act of dimerization activates Pro-Caspase-9, leading to its autocleavage into p35 and p12 subunits or to its activation of Caspase-3. Activated Caspase-3 can also act on Pro-Caspase-9, generating a 37 kDa subunit and a 10 kDa subunit.
| Alternate Names: | IDN-6556,PF-03491390 |
| Chemical Name: | N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, Simple Western, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SZ29-01 |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: Caspase-9 Antibody (SZ29-01)(Pro and Active) [NBP2-67362]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-SZ29-01-Pro-and-Active-Western-Blot-NBP2-67362-img0008.jpg "Western Blot: Caspase-9 Antibody (SZ29-01)(Pro and Active) [NBP2-67362]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human, Mouse, Rat, Canine, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Immunohistochemistry: Caspase-9 Antibody [NB100-56118]](https://resources.bio-techne.com/images/products/Caspase-9-Antibody-Immunohistochemistry-NB100-56118-img0014.jpg "Immunohistochemistry: Caspase-9 Antibody [NB100-56118]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Applications: | WB, IHC |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Conjugate
Catalog #
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #LAP6 |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |