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Caspase-9 Products

Caspase-9, also known as APAF-3, Mch6, and ICE-LAP6, is a 35-37 kDa member of the peptidase C14A family of enzymes. Caspase-9 is an initiator caspase that is part of the intrinsic apoptosis pathway. It is widely expressed and is particularly important during development. Following the mitochondrial disruption, Cytochrome c is released from mitochondria and interacts with APAF-1, resulting in Pro-Caspase-9 dimerization. The act of dimerization activates Pro-Caspase-9, leading to its autocleavage into p35 and p12 subunits or to its activation of Caspase-3. Activated Caspase-3 can also act on Pro-Caspase-9, generating a 37 kDa subunit and a 10 kDa subunit.

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158 results for "Caspase-9" in Products

158 results for "Caspase-9" in Products

Caspase-9 Products

Caspase-9, also known as APAF-3, Mch6, and ICE-LAP6, is a 35-37 kDa member of the peptidase C14A family of enzymes. Caspase-9 is an initiator caspase that is part of the intrinsic apoptosis pathway. It is widely expressed and is particularly important during development. Following the mitochondrial disruption, Cytochrome c is released from mitochondria and interacts with APAF-1, resulting in Pro-Caspase-9 dimerization. The act of dimerization activates Pro-Caspase-9, leading to its autocleavage into p35 and p12 subunits or to its activation of Caspase-3. Activated Caspase-3 can also act on Pro-Caspase-9, generating a 37 kDa subunit and a 10 kDa subunit.

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Reactivity: Human, Mouse, Rat, Canine, Gerbil
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, Flow, IP
Immunohistochemistry: Caspase-9 Antibody [NB100-56118]
(8)

Potent pan-caspase inhibitor

Chemical Name: N-[2-(1,1-Dimethylethyl)phenyl]-2-oxoglycyl-N-[(1S)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]-L-alaninamide
Purity: ≥98% (HPLC)
Potent pan-caspase inhibitor
Reactivity: Human, Mouse, Rat, Canine
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF, IP, Simple Western
Western Blot: Caspase-9 Antibody [NB100-56119]
(3)
Reactivity: Human
Details: Mouse IgG1 kappa Monoclonal Clone #LAP6 96-2-22
Applications: IHC, WB, ICC/IF, Mycoplasma, Simple Western
Western Blot: Caspase-9 Antibody (LAP6 96-2-22)BSA Free [NB500-209]
(5)

Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #SZ29-01
Applications: IHC, WB, ICC/IF, IP
Western Blot: Caspase-9 Antibody (SZ29-01)(Pro and Active) [NBP2-67362]
(8)

Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

Chemical Name: 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione
Purity: ≥98% (HPLC)
Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, IP
Western Blot: Caspase-9 [p Ser196] Antibody [NB100-56122]
(2)
Reactivity: Human, Primate
Details: Mouse IgG1 Monoclonal Clone #2-22
Applications: IHC, WB, IP
Western Blot: Caspase-9 Antibody (2-22) [NBP1-19231]
(4)
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, ELISA, ICC/IF, IP
Western Blot: Caspase-9 AntibodyBSA Free [NBP1-76961]
(6)
Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunocytochemistry/ Immunofluorescence: Caspase-9 Antibody [NBP1-90142]
(4)
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