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168 results for "Caspase-4" in Products
Caspase-4 Products
Caspase-11 (also known as as Caspase-4) is a cysteine-aspartic acid protease that functions in apoptosis initiation and the activation of proinflammatory cytokines. Pro-Caspase-11 is expressed as a zymogen which is cleaved into two subunits, p20 and p10. It is activated by an autocatalytic mechanism or by Caspase-8 mediated cleavage in response to ER stress or bacterial infection. Its expression and activation can be induced by exposure to LPS. Caspase-11 is one of several caspases associated with the inflammasome and plays an important role in the activation of proinflammatory cytokines. The active enzyme can cleave and activate Caspase-1 which in turn activates IL-1 beta.
Reactivity:
Multi-Species
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, ICC/IF
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA
Alternate Names:
Belnacasan
Chemical Name:
N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide
Purity:
≥98%
Reactivity:
Human
Details:
Mouse IgG2a Kappa Monoclonal Clone #7G7
Applications:
WB, ELISA
Alternate Names:
Belnacasan
Chemical Name:
N-(4-Amino-3-chlorobenzoyl)-3-methyl-L-valyl-N-[(2R,3S)-2-ethoxytetrahydro-5-oxo-3-furanyl]-L-prolinamide
Purity:
≥98%
Reactivity:
Human
Source:
Wheat germ
Applications:
WB, ELISA, AP, Endotoxin
Reactivity:
Mouse
Assay Range:
1.56 - 100 ng/mL
Applications:
ELISA
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA
Reactivity:
Human
Assay Range:
0.16 - 10 ng/mL
Applications:
ELISA
Reactivity:
Human
Assay Range:
0.16 - 10 ng/mL
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #OTI4A2
Applications:
WB
Reactivity:
Human
Applications:
WB
Reactivity:
Human
Applications:
WB
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #OTI4A2
Applications:
WB
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
ICC/IF
Reactivity:
Human
Source:
E. coli
Applications:
AC
Reactivity:
Non-species specific
Applications:
Func
Reactivity:
Human
Source:
Synthetic
Applications:
AC
Reactivity:
Human
Source:
Synthetic
Applications:
AC
Reactivity:
Human
Source:
Synthetic
Applications:
AC