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Casein Kinase 1 Inhibitors Products
Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. The C-termini of the CK1 gamma isoforms carry putative palmitoylation sites. CK2 is a tetrameric kinase comprised of two catalytic subunits (CK2 alpha and/or CK2 alpha‘) and two identical regulatory subunits (CK2 beta).
10 results for "Casein Kinase 1 Inhibitors" in Products
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Casein Kinase 1 Inhibitors Products
Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. The C-termini of the CK1 gamma isoforms carry putative palmitoylation sites. CK2 is a tetrameric kinase comprised of two catalytic subunits (CK2 alpha and/or CK2 alpha‘) and two identical regulatory subunits (CK2 beta).
10 results for "Casein Kinase 1 Inhibitors" in Products
Selective CK1 inhibitor. Also inhibits TGF-βRI
| Chemical Name : | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity : | ≥99% (HPLC) |
CK1 inhibitor
| Chemical Name : | N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride |
| Purity : | ≥99% (HPLC) |
Selective casein kinase 1ε inhibitor
| Chemical Name : | 3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride |
| Purity : | ≥99% (HPLC) |
Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
| Chemical Name : | 2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanol dihydrochloride |
| Purity : | ≥98% (HPLC) |
Potent and selective CK1ε and CK1δ inhibitor
| Chemical Name : | 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride |
| Purity : | ≥99% (HPLC) |
Potent p38 MAPK inhibitor; anti-inflammatory
| Chemical Name : | N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide |
| Purity : | ≥99% (HPLC) |
CK1 inhibitor; displays selectivity for CK1δ and CK1ε
| Chemical Name : | 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one |
| Purity : | ≥98% (HPLC) |
CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal
| Chemical Name : | 6-(3-Chlorophenyl)-2,4,7-pteridinetriamine |
| Purity : | ≥98% (HPLC) |
Cdk inhibitor; potently inhibits cdk1 and cdk2; also inhibits CK1; acts as molecular glue
| Chemical Name : | (2R)-2-[[9-(Methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-1-butanol trihydrochloride |
| Purity : | ≥99% (HPLC) |
Potent CK1δ/ε inhibitor
| Chemical Name : | 4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-pyrimidinamine |
| Purity : | ≥98% (HPLC) |
