26 results for "BRD3" in Products
BRD3 Products
BRD3 was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF, ChIP |
![Immunocytochemistry/ Immunofluorescence: BRD3 Antibody [NBP2-14360]](https://resources.bio-techne.com/images/products/BRD3-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-14360-img0006.jpg "Immunocytochemistry/ Immunofluorescence: BRD3 Antibody [NBP2-14360]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #BLR069G |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: BRD3 Antibody (BLR069G) [NBP2-77359]](https://resources.bio-techne.com/images/products/BRD3-Antibody-BLR069G-Western-Blot-NBP2-77359-img0003.jpg "Western Blot: BRD3 Antibody (BLR069G) [NBP2-77359]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #6E7 |
| Applications: | IHC, WB, ELISA |
![Western Blot: BRD3 Antibody (6E7) [H00008019-M01]](https://resources.bio-techne.com/images/products/BRD3-Antibody-6E7-Western-Blot-H00008019-M01-img0007.jpg "Western Blot: BRD3 Antibody (6E7) [H00008019-M01]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: BRD3 Antibody [NBP2-15612]](https://resources.bio-techne.com/images/products/BRD3-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-15612-img0004.jpg "Immunocytochemistry/ Immunofluorescence: BRD3 Antibody [NBP2-15612]")
| Reactivity: | Human |
| Details: | Mouse IgG3 Kappa Monoclonal Clone #7G6 |
| Applications: | IHC, WB, ELISA |
![Western Blot: BRD3 Antibody (7G6) [H00008019-M02]](https://resources.bio-techne.com/images/products/BRD3-Antibody-7G6-Western-Blot-H00008019-M02-img0007.jpg "Western Blot: BRD3 Antibody (7G6) [H00008019-M02]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #6F3 |
| Applications: | IHC, WB, ELISA |
![Western Blot: BRD3 Antibody (6F3) [H00008019-M04]](https://resources.bio-techne.com/images/products/BRD3-Antibody-6F3-Western-Blot-H00008019-M04-img0006.jpg "Western Blot: BRD3 Antibody (6F3) [H00008019-M04]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![BRD3 Antibody Immunocytochemistry/Immunofluorescence: BRD3 Antibody [NBP3-25303]](https://resources.bio-techne.com/images/products/nbp3-25303_rabbit-brd3-pab-191220231695416.jpg "Immunocytochemistry/Immunofluorescence: BRD3 Antibody [NBP3-25303]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human BRD3 His Protein [NBP2-51919]](https://resources.bio-techne.com/images/products/BRD3-Recombinant-Protein-SDS-Page-NBP2-51919-img0001.jpg "SDS-PAGE: Recombinant Human BRD3 His Protein [NBP2-51919]")
| Applications: | WB |
BET bromodomain inhibitor; orally bioavailable
| Alternate Names: | Birabresib |
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% (HPLC) |
(+)-JQ1 based Degrader (PROTAC®) that preferentially degrades BRD4
| Chemical Name: | (2S,4R)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective BET bromodomain inhibitor; cell permeable
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester |
| Purity: | ≥98% (HPLC) |
Potent and selective (+)-JQ1 based Degrader (PROTAC®) targeting BET bromodomains, active in vivo
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-N-[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% (HPLC) |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Alternate Names: | TEN 010 |
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% (HPLC) |
(+)-JQ1 based Degrader (PROTAC®) targeting BET bromodomains, active in vivo
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% (HPLC) |
Potent BET bromodomain PROTAC®; also degrades BRD-tagged chimeric antigen receptors (CAR) in T cells
| Chemical Name: | (2S,4R)-1-((S)-2-(tert-Butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective pan-BD2 inhibitor; orally bioavailable
| Alternate Names: | GSK046 |
| Chemical Name: | 4-(Acetylamino)-3-fluoro-N-(trans-4-hydroxycyclohexyl)-5-[(1S)-1-phenylethoxy]benzamide |
| Purity: | ≥98% (HPLC) |
BET bromodomain inhibitor; also promotes differentiation of hiPSCs into megakaryocytes
| Chemical Name: | 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable.
| Alternate Names: | GSK525762A,Molibresib |
| Chemical Name: | (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide |
| Purity: | ≥98% (HPLC) |
Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor
| Chemical Name: | 1,1-Dimethylethyl 4-[3-amino-6-(2-hydroxyphenyl)-4-pyridazinyl]-1-piperazinecarboxylate bromodomains |
| Purity: | ≥98% (HPLC) |
