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BMPR-IA/ALK-3: Proteins and Enzymes
Cellular responses to bone morphogenetic proteins (BMPs) are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. There are seven known type I serine/threonine kinases and five mammalian type II serine/threonine kinase receptors that function in TGF-beta superfamily signal transduction. The type II receptors for TGF-beta and activin bind ligands with high affinity by themselves. In contrast, BMPR-II binding to BMP-2, BMP-4, and BMP-7 is facilitated by the presence of the type I receptor. The type I receptors are also known as activin receptor-like kinases or ALKs.
4 results for "BMPR-IA/ALK-3 Proteins and Enzymes" in Products
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BMPR-IA/ALK-3: Proteins and Enzymes
Cellular responses to bone morphogenetic proteins (BMPs) are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. There are seven known type I serine/threonine kinases and five mammalian type II serine/threonine kinase receptors that function in TGF-beta superfamily signal transduction. The type II receptors for TGF-beta and activin bind ligands with high affinity by themselves. In contrast, BMPR-II binding to BMP-2, BMP-4, and BMP-7 is facilitated by the presence of the type I receptor. The type I receptors are also known as activin receptor-like kinases or ALKs.
4 results for "BMPR-IA/ALK-3 Proteins and Enzymes" in Products
A New rm BMPR-IA is Available! It has ~1.5 fold better, lower endotoxin specification, and a Fc tag!
| Source : | NS0 |
| Accession # : | NP_004320 |
| Applications : | Bioactivity |
A New rh BMPR-IA is Available! ~2 fold better activity; Lower endotoxin specification; Enhanced purity!
| Source : | NS0 |
| Accession # : | NP_033888 |
| Applications : | Bioactivity |
