Sign In / Register
B7-2/CD86: Proteins and Enzymes
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
11 results for "B7-2/CD86 Proteins and Enzymes" in Products
Application
Conjugates
Low Endotoxin
Sample Size
Citations
Reviews
B7-2/CD86: Proteins and Enzymes
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
11 results for "B7-2/CD86 Proteins and Enzymes" in Products
Catalog #:
141-B2
BA
A New rh B7-2 is Available! It has higher purity, ~3 fold better activity, and is HEK293 expressed!
A New rh B7-2 protein is Available! It is HEK293 expressed with a His-tag!
Catalog #:
9090-B2
BA
An alternative B7-2 is now available! 7625-B2 has a Fc Chimera tag and is CHO expressed.
Catalog #:
741-B2
BA
| Source : | Sf 21 (baculovirus) |
| Accession # : | Q549Q9 |
| Applications : | Bioactivity |
Catalog #:
9798-B2
BA
Fc Chimera
| Source : | HEK293 |
| Accession # : | XP_005548057 |
| Applications : | Bioactivity |
Catalog #:
10300-B2
BA
| Source : | HEK293 |
| Accession # : | XP_005548057 |
| Applications : | Bioactivity |
Catalog #:
1340-B2
BA
| Source : | NS0 |
| Accession # : | O35531 |
| Applications : | Bioactivity |
Catalog #:
AFR9090
BA
| Source : | HEK293 |
| Accession # : | NP_787058.4 |
| Applications : | Bioactivity |
