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B7-2/CD86 Products

B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.

50 results for "B7-2/CD86" in Products

B7-2/CD86 Products

B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.

50 results for "B7-2/CD86" in Products

Catalog #: MAB1412
ELISA
WB, IHC, KO, Neut
Flow
WB, Flow, CyTOF-ready, KO, Neut
WB, Flow, CyTOF-ready, Neut
Neut
ELISA
BA

A New rh B7-2 is Available! It has higher purity, ~3 fold better activity, and is HEK293 expressed!

BA

Fc Chimera

Catalog #: FAB141G
Flow
Catalog #: 7625-B2
BA

A New rh B7-2 protein is Available! It is HEK293 expressed with a His-tag!

BA

An alternative B7-2 is now available! 7625-B2 has a Fc Chimera tag and is CHO expressed.

BA

Biotinylated

Catalog #: BAF441
WB
WB, Flow, IHC, CyTOF-ready
BA
Catalog #: 1340-B2
BA
BA
BA

Fc Chimera

BA

Fc Chimera

BA
Catalog #: FAB141V
Flow
WB, IHC, KO
Catalog #: FAB141S
Flow
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