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B7-2/CD86 Products
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
50 results for "B7-2/CD86" in Products
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B7-2/CD86 Products
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
50 results for "B7-2/CD86" in Products
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Immunohistochemistry, Knockout Validated, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37301 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Knockout Validated, Western Blot |
| Assay Range : | 46.9 - 3,000 pg/mL |
| Applications : | ELISA |
A New rh B7-2 is Available! It has higher purity, ~3 fold better activity, and is HEK293 expressed!
| Source : | NS0 |
| Accession # : | AAB03814 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37301 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37301 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Block/Neutralize, Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #GL1 |
| Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Immunohistochemistry, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37301 |
| Applications : | Flow Cytometry |
| Source : | Sf 21 (baculovirus) |
| Accession # : | Q549Q9 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1029808 |
| Applications : | Immunohistochemistry, Knockout Validated, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #199622 |
| Applications : | Block/Neutralize |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #37301 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #GL1 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1036431 |
| Applications : | Immunohistochemistry |
| Source : | HEK293 |
| Accession # : | XP_005548057 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunohistochemistry, Western Blot |
| Source : | HEK293 |
| Accession # : | NP_787058.4 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #199602 |
| Applications : | Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #GL1 |
| Applications : | Flow Cytometry |
