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B7-2/CD86: Antibodies

B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.

34 results for "B7-2/CD86 Primary Antibodies" in Products

B7-2/CD86: Antibodies

B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.

34 results for "B7-2/CD86 Primary Antibodies" in Products

Flow
Neut
WB, Flow, CyTOF-ready, KO, Neut
Catalog #: FAB141G
Flow
WB, Flow, CyTOF-ready, Neut
Catalog #: MAB1340
WB
Catalog #: BAF441
WB
WB, Flow, IHC, CyTOF-ready
Catalog #: FAB141V
Flow
WB, IHC, KO, Neut
Flow
WB, IHC, KO
Catalog #: FAB141S
Flow
Flow
Flow
Catalog #: MAB1412
ELISA
IHC
Catalog #: MAB10852
ELISA
Catalog #: MAB1411
ELISA
Catalog #: FAB741S
Flow
Catalog #: FAB741U
Flow
Catalog #: BAF141
WB
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