B7-2/CD86: Antibodies
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
34 results for "B7-2/CD86 Primary Antibodies" in Products
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B7-2/CD86: Antibodies
B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.
34 results for "B7-2/CD86 Primary Antibodies" in Products
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #199622 |
Applications : | Block/Neutralize |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #GL1 |
Applications : | Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #199602 |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | CyTOF-ready, ELISA Capture, Flow Cytometry, Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1029808 |
Applications : | Immunohistochemistry, Knockout Validated, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #GL1 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1036438 |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1036431 |
Applications : | Immunohistochemistry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1036426 |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37324 |
Applications : | ELISA |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #GL1 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #GL1 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #37301 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Rat IgG2a Clone #GL1 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |