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Angiopoietin-like Protein 3/ANGPTL3 Products
Angiopoietin-like Protein 3 (ANGPTL3) is a secreted glycoprotein that is primarily expressed in the liver. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N- and C-terminal fragments containing the coiled coil domain and fibrinogen-like domains, respectively. ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids. It promotes an increase in circulating triglyceride levels without altering VLDL or HDL secretion or uptake. ANGPTL3 is upregulated by LXR agonists and downregulated by Insulin, Leptin, and agonists of TR beta or PPAR beta. Its fibrinogen-like domain interacts with Integrin alphaV beta3 to induce endothelial cell adhesion, migration, and neovascularization. ANGPTL3 also promotes the expansion of hematopoietic stem cells.
34 results for "Angiopoietin-like Protein 3/ANGPTL3" in Products
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Angiopoietin-like Protein 3/ANGPTL3 Products
Angiopoietin-like Protein 3 (ANGPTL3) is a secreted glycoprotein that is primarily expressed in the liver. Full length ANGPTL3 circulates in the plasma as do the proteolytically separated N- and C-terminal fragments containing the coiled coil domain and fibrinogen-like domains, respectively. ANGPTL3 directly inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), enzymes responsible for hydrolyzing circulating triglycerides and HDL phospholipids. It promotes an increase in circulating triglyceride levels without altering VLDL or HDL secretion or uptake. ANGPTL3 is upregulated by LXR agonists and downregulated by Insulin, Leptin, and agonists of TR beta or PPAR beta. Its fibrinogen-like domain interacts with Integrin alphaV beta3 to induce endothelial cell adhesion, migration, and neovascularization. ANGPTL3 also promotes the expansion of hematopoietic stem cells.
34 results for "Angiopoietin-like Protein 3/ANGPTL3" in Products
| Source : | Sf 21 (baculovirus) |
| Accession # : | Q9R182 |
| Applications : | Inhibition Activity |
| Source : | Sf 21 (baculovirus) |
| Accession # : | Q9Y5C1 |
| Applications : | Bioactivity, Inhibition Activity |
| Source : | NS0 |
| Accession # : | Q9R182 |
| Applications : | Bioactivity |
| Source : | T. ni (baculovirus) |
| Accession # : | XP_005543242 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | ELISA Detection, Immunohistochemistry, Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | ELISA Detection, Western Blot |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #388610 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #128644 |
| Applications : | Western Blot |
Simple Plex Human Angiopoietin-like Protein 3/ANGPTL3 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Sensitivity : | 0.035 ng/mL |
| Assay Range : | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies
N-Terminal Fragment
| Source : | CHO |
| Accession # : | Q9R182 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | Q9R182 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | Q9Y5C1 |
| Applications : | Inhibition Activity |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #128611 |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #370207 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #388620 |
| Applications : | ELISA Capture |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #128610 |
| Applications : | Western Blot |
| Sensitivity : | 9.62 pg/mL |
| Assay Range : | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies
Simple Plex Mouse Angiopoietin-like 3 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Assay Range : | 31.2 - 2,000 pg/mL |
| Applications : | ELISA |
