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10 results for "Androgen R/NR3C4 Small Molecules and Peptides" in Products

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Androgen R/NR3C4 Small Molecules and Peptides

Human Androgen Receptor (AR; NR3C4) is a 110 kDa member of the NR3 subfamily of the nuclear hormone receptor family. Androgen receptors are expressed by androgen-sensitive tissue (bone, prostate, testis) and exist as both ahomodimers and a heterodime in a complex with the glucocorticoid receptor. Multiple forms of the androgen receptor are known to exist. The 110 kDa 'B' form is 919 amino acids in length. Phosphorylation increases its molecular weight to 112 kDa and 114 kDa. A five amino acid ...

Mifepristone

Catalog #: 1479

Citations (58)

Product Documents

Images (1)

Progesterone and glucocorticoid receptor antagonist

Alternate Names:

RU 486,RU 38486

Chemical Name:

(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one

Purity:

≥98%

TFM-4AS-1

Catalog #: 3813

Citations (1)

Product Documents

Images (1)

Selective androgen receptor modulator (SARM)

Chemical Name:

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,11a-Trimethyl-7-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide

Purity:

≥98%

ARCC 4

Catalog #: 7254

Citations (7)

Product Documents

Images (1)

Potent and selective androgen receptor Degrader (PROTAC®)

Chemical Name:

(2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Purity:

≥98%

Spironolactone

Catalog #: 2968

Citations (17)

Product Documents

Images (1)

Mineralocorticoid receptor antagonist

Alternate Names:

SC 9420,Aldactone

Chemical Name:

(7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone

Purity:

≥98%

Cl-4AS-1

Catalog #: 3812

Citations (8)

Product Documents

Images (1)

Steroidal androgen receptor agonist

Chemical Name:

(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)-N-(2-Chlorophenyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1,4,6a-trimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide

Purity:

≥98%

Flutamide

Catalog #: 4094

Citations (26)

Product Documents

Images (1)

Non-steroidal androgen receptor antagonist

Alternate Names:

SCH 13521

Chemical Name:

2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide

Purity:

≥98%

Galeterone

Catalog #: 6108

Product Documents

Images (1)

CYP17 inhibitor; also androgen receptor antagonist

Alternate Names:

TOK-001,VN/124-1

Chemical Name:

(3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol

Purity:

≥98%

ARCC 4 negative control

Catalog #: 7255

Citations (1)

Product Documents

Images (1)

Negative control for ARCC 4 (Cat. No. 7254)

Chemical Name:

(2S,4S)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Purity:

≥98%

AZ 3137

Catalog #: 8833

Product Documents

Images (1)

Potent and selective AR and AR L702H Degrader, orally bioavailable

Chemical Name:

4-[4-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-7-methoxy-1-oxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]phenyl]-1-piperidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile

Purity:

≥98%

CCS 1477

Catalog #: 8892

Product Documents

Images (1)

Selective p300/CBP bromodomain inhibitor

Chemical Name:

(6S)-1-(3,4-Difluorophenyl)-6-[5-(3,5-dimethyl-4-isoxazolyl)-1-(trans-4-methoxycyclohexyl)-1H-benzimidazol-2-yl]-2-piperidinone

Purity:

≥98%

Results Per Page

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Androgen R/NR3C4 Small Molecules and Peptides

Mifepristone

TFM-4AS-1

ARCC 4

Spironolactone

Cl-4AS-1

Flutamide

Galeterone

ARCC 4 negative control

AZ 3137

CCS 1477

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