
alpha-L-Iduronidase/IDUA: Proteins and Enzymes
alpha-L-Iduronidase, encoded by the IDUA gene, is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non-reducing terminal a-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue, and organ damage.
4 results for "alpha-L-Iduronidase/IDUA Proteins and Enzymes" in Products
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alpha-L-Iduronidase/IDUA: Proteins and Enzymes
alpha-L-Iduronidase, encoded by the IDUA gene, is an important enzyme required for the lysosomal degradation of glycosaminoglycans (GAGs). It hydrolyzes the non-reducing terminal a-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. Mutations in IDUA that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). MPS I causes progressive cellular, tissue, and organ damage.
4 results for "alpha-L-Iduronidase/IDUA Proteins and Enzymes" in Products
NS0-expressed
Source : | NS0 |
Accession # : | AAA81589 |
Applications : | Enzyme Activity |
CHO-expressed (aa 28-653 H33Q)
Source : | CHO |
Accession # : | P35475.2 |
Applications : | Enzyme Activity |
Source : | NS0 |
Accession # : | P48441 |
Applications : | Enzyme Activity |
CHO-expressed (aa 26-653)
Source : | CHO |
Accession # : | P35475.2 |
Applications : | Enzyme Activity |