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Akt1 Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
50 results for "Akt1" in Products
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Akt1 Products
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
50 results for "Akt1" in Products
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence |
| Applications : | ELISA |
| Clonality : | Monoclonal |
| Host : | Mouse IgG3 Clone #658320 |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #232790 |
| Applications : | Knockout Validated, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #710022 |
| Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
| Assay Range : | 312 - 20,000 pg/mL |
| Applications : | ELISA |
| Source : | Sf 9 (baculovirus) |
| Accession # : | NM_005163 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #302407 |
| Applications : | Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Rabbit IgG |
| Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Simple Western, Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #281046 |
| Applications : | CyTOF-ready, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
Akt/PKB inhibitor
| Chemical Name : | Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #545007 |
| Applications : | Simple Western, Western Blot |
Potent and selective dual Akt1 and 2 inhibitor
| Alternate Names : | Akt Inhibitor VIII |
| Chemical Name : | 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Purity : | ≥98% (HPLC) |
PI 3-K/Akt/mTOR signaling inhibitor; blocks phosphorylation of Akt and p70S6K in vitro
| Chemical Name : | 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one |
| Purity : | ≥98% (HPLC) |
| Assay Range : | 156 - 10,000 pg/mL |
| Applications : | ELISA |
Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor
| Chemical Name : | 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride |
| Purity : | ≥98% (HPLC) |
