Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway|
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Citations for SAG (5)
Citations are publications that use Bio-Techne products. Selected citations for SAG include:
Haidar et al.
Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.
Atzmon et al.
Drug Screening Identifies Sigma-1-Receptor as a Target for the Therapy of VWM Leukodystrophy.
Front Mol Neurosci.
Rajamani et al.
Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses.
Cell Stem Cell.
Xia et al.
Transcriptional comparison of human induced and primary midbrain DArgic neurons.
Cortes et al.
Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation.
Nat Chem Biol.
There are no citations that match your criteria.
Customer Reviews for SAG (2)
Species: HumanAssay Type: In VitroCell Line/Tissue: HepG2, and Huh,SAG consistently produced positive results in our experiments; it promoted the formation of cilia and reduced the proliferation of cancer cells.We use 5-20 nm concentration for 24-48 hours.
Species: MouseAssay Type: In VitroCell Line/Tissue: iPSCiPSC-derived hypothalamic neuron differentiation activation by Smoothened agonist SAG 1 μM and purmorphamine 1 μM.From Day 2 to day 9 to direct the cells toward ventral diencephalon with regular media change every 2 days.
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