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SAG

Tocris Bioscience a Bio-Techne Brand

SAG | CAS No. 912545-86-9 | Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
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4366/1
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Key Product Details

Description: Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
Chemical Name: 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide
Purity: ≥98% (HPLC)
Molecular Weight: 490.06

Citations for SAG (5)

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Customer Reviews for SAG (2)

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  • Promoted the formation of cilia
    Name: Kishor Pant
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HepG2, and Huh,
    SAG consistently produced positive results in our experiments; it promoted the formation of cilia and reduced the proliferation of cancer cells.
    We use 5-20 nm concentration for 24-48 hours.
    SAG Serum 4366
  • Usage Information
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: iPSC
    iPSC-derived hypothalamic neuron differentiation activation by Smoothened agonist SAG 1 μM and purmorphamine 1 μM.
    From Day 2 to day 9 to direct the cells toward ventral diencephalon with regular media change every 2 days.
    SAG Serum 4366

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Product Documents for SAG

Certificate of Analysis

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