Tocris Bioscience a Bio-Techne Brand
Key Product Details
|Description:||Antibiotic. Displays neuroprotective effects|
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Citations for Minocycline hydrochloride (2)
Citations are publications that use Bio-Techne products. Selected citations for Minocycline hydrochloride include:
Yaeger and Trussell
Single granule cells excite Golgi cells and evoke feedback inhibition in the cochlear nucleus.
Song et al.
MinCyc does not affect long-term potentiation in the anterior cingulate cortex of normal adult mice.
Hum Mol Genet.
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Customer Reviews for Minocycline hydrochloride (1)
Species: MouseAssay Type: In VivoCell Line/Tissue: BrainI have used the antibiotic minocycline to impair activation of microglia in the brain of mice. This drug has anti-inflammatory properties that block microglial reactivity, which can be easily confirmed by expression of the CD68 protein. The drug was diluted in PBS and injected i.p. (75 mg/kg) in mice, twice a day, for 7 days. The image shows that microglial cells (stained for Iba1) do not express CD68 (in red) after treatment with minocycline.
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⚠ WARNING: This product can expose you to chemicals including Minocycline hydrochloride (internal use), which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov