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AT 1

Active Degraders Small Molecule
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6356/5

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Bio-Techne Corporation
tel: (800) 343-7475 (free phone)
tel: (612) 379-2956

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$35 to United States

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Key Product Details

Description: (+)-JQ1 based PROTAC® with selectivity for BRD4
Chemical Name: (2S,4R)-1-(2R)-2-Acetamido-3-[[6-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamido]hexyl]thio]-3-methylbutanoyl]-4-hydroxy-N-[4-(4-methylthiazol-5-yl)benzyl)pyrrolidinine-2-carboxamide
Purity: ≥98% (HPLC)
Molecular Weight: 972.68

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  • AT1 PROTAC
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: glioblastoma
    We tested the effect of AT1 PROTAC in degrading the endogenous BRD4 protein in glioblastoma cell lines with varying concentrations of AT1 starting from 100nM, 300nM and 1 uM.
    AT 1 Serum 6356

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