Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | HEK293 |
Accession #: | YP_009724390.1 |
Applications: | Bioactivity |
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Citations for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF
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FAQs for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF
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What is meant by "Resistant to Furin & Stabilized Prefusion Conformation?" in the description for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF (Catalog # 10748-CV)?
Furin cleavage resistance is conferred by the Arg682Ser and Arg685Ser mutations. The mutations Lys986Pro and Val987Pro stabilize and promote the prefusion conformation of this Spike protein.