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Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF

R&D Systems, Inc. a Bio-Techne Brand

Alpha Variant (UK) Resistant to Furin & Stabilized Prefusion Conformation
(3)
Surface plasmon resonance (SPR) sensorgram of Human ACE-2 binding to UK variant B.1.1.7 Spike mutant protein
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10748-CV-100
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Key Product Details

Source: HEK293
Accession #: YP_009724390.1
Applications: Bioactivity

Citations for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF


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FAQs for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF

  • What is meant by "Resistant to Furin & Stabilized Prefusion Conformation?" in the description for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF (Catalog # 10748-CV)?

    Furin cleavage resistance is conferred by the Arg682Ser and Arg685Ser mutations. The mutations Lys986Pro and Val987Pro stabilize and promote the prefusion conformation of this Spike protein.

Product Documents for Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag Protein, CF

Certificate of Analysis

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