Spike Products
The Coronavirus Spike protein (S Protein) is one of four major structural proteins (S, M, E, N) present in each viral particle. Spike proteins are abundantly expressed on the surface forming its characteristic crown-like halo structure. The Spike protein is a highly glycosylated, type I transmembrane protein that plays a critical role in receptor recognition and host cell entry. There are two subunits, S1 and S2, that divide the protein roughly in half. Within the N-terminal S1 subunit is the N-terminal domain and receptor binding domain (Spike RBD protein). The Spike RBD binds to the host cell and undergoes several conformational changes and proteolysis leading to fusion of the virus particle to the host cell membrane allowing transfer of the nucleocapsid into the host cell cytoplasm. For SARS-CoV-2, the virus responsible for the COVID-19 pandemic, the Spike RBD tightly associates with human ACE-2. Recombinant SARS-CoV-2 proteins and antibodies that recognize these proteins are essential for studying the molecular mechanisms of the coronavirus life cycle.
111 results for "Spike" in Products
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Spike Products
The Coronavirus Spike protein (S Protein) is one of four major structural proteins (S, M, E, N) present in each viral particle. Spike proteins are abundantly expressed on the surface forming its characteristic crown-like halo structure. The Spike protein is a highly glycosylated, type I transmembrane protein that plays a critical role in receptor recognition and host cell entry. There are two subunits, S1 and S2, that divide the protein roughly in half. Within the N-terminal S1 subunit is the N-terminal domain and receptor binding domain (Spike RBD protein). The Spike RBD binds to the host cell and undergoes several conformational changes and proteolysis leading to fusion of the virus particle to the host cell membrane allowing transfer of the nucleocapsid into the host cell cytoplasm. For SARS-CoV-2, the virus responsible for the COVID-19 pandemic, the Spike RBD tightly associates with human ACE-2. Recombinant SARS-CoV-2 proteins and antibodies that recognize these proteins are essential for studying the molecular mechanisms of the coronavirus life cycle.
111 results for "Spike" in Products
Biotinylated via Amines
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Ectodomain, Stabilized Prefusion Conformation, Resistant to Furin Cleavage
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
(1-1273 4x aa mut.)
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
(GCN4-IZ) His-tag Gamma (Brazilian) Variant
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
CHO expressed. GCN4-IZ trimerization domain. Prefusion Conformation. High ACE-2 binding
Source : | CHO |
Accession # : | YP_009825051.1 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | QHR63300.2 |
Applications : | Bioactivity |
His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
His-tag Biotinylated
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | YP_007188579.1 |
Applications : | Bioactivity |
Alpha Variant (UK) with E484K Point Mutation. His-tag.
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
(GCN4-IZ) Gamma (Brazilian) Variant His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
(GCN4-IZ) His-tag India Variant (Delta)
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Omicron Variant (GCN4-IZ) His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Omicron Variant (GCN4-IZ) His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
His-tag Biotinylated Delta Variant (India)
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Source : | CHO |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Omicron Variant Biotinylated His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Alpha Variant (UK) Resistant to Furin & Stabilized Prefusion Conformation
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
GCN4-IZ trimerization domain, Stabilized Prefusion Conformation, Resistant to Furin Cleavage
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | YP_009724390.1 |
His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Beta Variant (South Africa)
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Source : | HEK293 |
Accession # : | P59594.1 |
Applications : | Bioactivity |