Human TGF-beta 1 Protein
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source: | Human Platelets |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
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Citations for Human TGF-beta 1 Protein (41)
Citations are publications that use Bio-Techne products. Selected citations for Human TGF-beta 1 Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: BioassayBE Decato et al. (2022), LPA1 antagonist BMS-986020 changes collagen dynamics and exerts antifibrotic effects in vitro and in patients with idiopathic pulmonary fibrosis Respiratory Research, 23(1):61.
PMID: 35303880 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJL Decano et al. (2022), A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling Cell Reports, 39(2):110685.
PMID: 35417712 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Chandrasek et al. (2022), UDP-glucose dehydrogenase (UGDH) activity is suppressed by peroxide and promoted by PDGF in fibroblast-like synoviocytes: Evidence of a redox control mechanism PLoS ONE, 17(9):e0274420.
PMID: 36107941 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Lu et al. (2021), PP2A Catalytic Subunit alpha promotes fibroblast activation and kidney fibrosis via ERK pathway Cellular Signalling, 90(0):110187.
PMID: 34780974 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Sharma et al. (2021), E4 engages uPAR and enolase-1 and activates urokinase to exert antifibrotic effects JCI Insight, 6(24).
PMID: 34935642 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySR Rønnow et al. (2020), Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis Respir. Res., 21(1):108.
PMID: 32381012 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureHH Wong et al. (2020), Red-COLA1: a human fibroblast reporter cell line for type I collagen transcription Sci Rep, 10(1):19723.
PMID: 33184327 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Tsubouchi et al. (2019), Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis J. Immunol., 0(0).
PMID: 31534007 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayX Xue et al. (2018), Protein kinase C alpha drives fibroblast activation and kidney fibrosis by stimulating autophagic flux J. Biol. Chem., 0(0).
PMID: 29794026 -
Species: Human
Sample Types: Cell Culture Treatment
Applications: BioassayQF Li et al. (2018), Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke Cell Rep, 24(11):2869-2882.
PMID: 30208313 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayE Engelowski et al. (2018), IL-23R Signaling Plays No Role in Myocardial Infarction Sci Rep, 8(1):17078.
PMID: 30459442 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Fu et al. (2017), Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression Mediators Inflamm., 2017(0):5706152.
PMID: 29056830 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayZ Zeng et al. (2017), Omega-3 Polyunsaturated Fatty Acids Attenuate Fibroblast Activation and Kidney Fibrosis Involving MTORC2 Signaling Suppression Sci Rep, 7(0):46146.
PMID: 28393852 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayJ Ren et al. (2016), Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and ?-catenin Signaling Sci Rep, 6(0):23968.
PMID: 27052477 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDayer C et al. (2015), Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-beta (TGF-beta) Activation and Fibroblast Differentiation. J Biol Chem, 290(22):13763-78.
PMID: 25825495 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayLi J et al. (2015), Rictor/mTORC2 signaling mediates TGFbeta1-induced fibroblast activation and kidney fibrosis. Kidney Int, 88(3):515-27.
PMID: 25970154 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPatsialou A et al. (2015), Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFbeta in claudin-low breast tumor cells. Oncogene, 34(21):2721-31.
PMID: 25088194 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBernard M et al. (2014), Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF. Autophagy, 10(12):2193-207.
PMID: 25495560 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDuan W et al. (2014), Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro. Am J Pathol, 184(8):2275-84.
PMID: 24925688 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXu L et al. (2014), Induction of high temperature requirement A1, a serine protease, by TGF-beta1 in articular chondrocytes of mouse models of OA. , 0(0).
PMID: 24135912 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayJiang L et al. (2013), Rheb/mTORC1 signaling promotes kidney fibroblast activation and fibrosis. J Am Soc Nephrol, 24(7):1114-26.
PMID: 23661807 -
Species: Rat
Sample Types: In Vivo
Applications: BioassayZhu Y et al. (2012), Transforming growth factor beta induces sensory neuronal hyperexcitability, and contributes to pancreatic pain and hyperalgesia in rats with chronic pancreatitis. Mol Pain, 8(0):65.
PMID: 22963239 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBruchard M et al. (2012), Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med, 19(1):57-64.
PMID: 23202296 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhang N et al. (2012), TGF-beta signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation. Nat. Immunol., 13(7):667-73.
PMID: 22634866 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKawamura T et al. (2012), Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency. J. Clin. Invest., 122(2):722-32.
PMID: 22214844 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKashiwakuma D et al. (2010), B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses. J. Immunol., 185(5):2730-6.
PMID: 20660710 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySuzuki H et al. (2010), VEGFR2 is selectively expressed by FOXP3high CD4+ Treg. Eur. J. Immunol., 40(1):197-203.
PMID: 19902430 -
Stumhofer JS et al. (2010), A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat. Immunol., 11(12):1119-26.
PMID: 21057510 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOgawa Y et al. (2009), Gram-positive bacteria enhance HIV-1 susceptibility in Langerhans cells, but not in dendritic cells, via Toll-like receptor activation. Blood, 113(21):5157-66.
PMID: 19279330 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGang EJ et al. (2008), Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage. Exp. Cell Res., 314(8):1721-33.
PMID: 18395202 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAlexander S et al. (2007), Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB. Arthritis Rheum., 56(11):3715-25.
PMID: 17968943 -
Species: Rat
Sample Types: In Vivo
Applications: In VivoMatsumura S et al. (2007), Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity. Neuroscience, 144(3):1133-40.
PMID: 17156928 -
Species: Human
Applications: BioassayNazareth MR et al. (2007), Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells. J. Immunol., 178(9):5552-62.
PMID: 17442937 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDavid L et al. (2007), Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood, 109(5):1953-61.
PMID: 17068149 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLindsley RC et al. (2006), Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development, 133(19):3787-96.
PMID: 16943279 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Mozaffarian D et al. (2004), trans fatty acids and systemic inflammation in heart failure. Am. J. Clin. Nutr., 80(6):1521-5.
PMID: 15585763 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWen FQ et al. (2004), Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads. Am. J. Respir. Cell Mol. Biol., 30(6):816-22.
PMID: 14722222 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZhou W et al. (2003), Dual regulation of proliferation and growth arrest in prostatic stromal cells by transforming growth factor-beta1. Endocrinology, 144(10):4280-4.
PMID: 12959966 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJono H et al. (2002), Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription. J. Biol. Chem., 277(47):45547-57.
PMID: 12237307 -
Species: Canine
Sample Types: Whole Cells
Applications: BioassayDepoortere F et al. (2000), Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1). Mol. Biol. Cell, 11(3):1061-76.
PMID: 10712520 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFadok et al. (1998), Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest, 101(4):890-8.
PMID: 9466984
There are no citations that match your criteria.
Customer Reviews for Human TGF-beta 1 Protein (4)
Customer Images
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Application: Evaluation of fibrosis induction after TGFb treatment.Verified Customer | Posted 08/17/2020
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Application: In vitro bioactivity in cell cultureReason for Rating: Excellent response in cell tissue studies at the NM level concentrationVerified Customer | Posted 11/03/2017
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Application: Immunoassay StandardVerified Customer | Posted 07/31/2017
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Application: In vitro bioactivity in cell cultureVerified Customer | Posted 07/21/2017
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