Will Recombinant Human TGF-beta 1 support the maintenance of either human or non-human cultured cells?

TGF-beta 1 performs multiple cellular functions, including cell growth, proliferation, differentiation and apoptosis. It would be necessary to determine the specific conditions for cell growth/proliferation for the cells being cultured.

Can Recombinant Human TGF beta 1 Protein (Catalog # 240-B or 240-B/CF) be reconstituted in PBS or water?

Recombinant Human TGF beta 1 Protein (Catalog # 240-B or 240-B/CF) needs to be reconstituted to 100 μg/mL in sterile 4 mM HCl containing 0.1% BSA or 4 mM HCl. This protein is hydrophobic by nature, so it requires an acidic buffer for reconstitution to go completely into solution. Stability testing has been evaluated on the protein with these reconstitution conditions; we can guarantee performance under these reconstitution conditions. When the protein is diluted with the cell culture media or buffers to the working concentration, the concentration of the acid should be buffered or negligible.

Has the half-life of recombinant human TGF beta 1 been determined?

While our Recombinant Human TGF-beta 1 Protein has been evaluated for bioactivity, the half-life of a specific protein will depend on experimental conditions, including the cell number, density, and media content. It is up to the end-user to determine the appropriate concentration and timing when adding Recombinant Human TGF-beta 1 Protein to individual experiments. For techniques and methodologies, we recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.

Recombinant Human TGF-beta 1 Protein

Name: Recombinant Human TGF-beta 1 Protein
Brand: rnd
SKU: 240-B
Rating: 5 (48 reviews)

Catalog # 240-B

Citations (671)

(48)

Datasheet / COA / SDS

New Version Available - 7754-BH

An alternative TGF-beta 1 is now available! 7754-BH is Hek293 expressed

Catalog #

Availability

Size / Price

Qty

Order Information

Bio-Techne Corporation

tel: (800) 343-7475 (free phone)

tel: (612) 379-2956

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

R&D Systems Guarantee

We offer a 100% guarantee on all our products.

Learn More »

Key Product Details

Source:	CHO
Accession #:	P01137
Structure / Form:	Disulfide-linked homodimer
Applications:	Bioactivity

View Full Technical Details for Recombinant Human TGF-beta 1 Protein

Complete Your Research

Product Specifications

Source	Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein Ala279-Ser390
Purity	>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Ala279
Predicted Molecular Mass	12.8 kDa (monomer)
SDS-PAGE	12 kDa, reducing conditions 24 kDa, non-reducing conditions
Activity	Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389. The ED₅₀ for this effect is 0.04-0.2 ng/mL. The specific activity of Recombinant Human TGF-beta 1 is approximately 2.5 x 10⁴ U/μg, which is calibrated against human TGF‑ beta 1 Standard (NIBSC code: 89/514).

Recombinant Human TGF-beta 1 Protein Scientific Data Examples

	Recombinant Human TGF-beta 1 Protein Bioactivity Recombinant Human TGF-beta 1 (Catalog # 240-B) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line. The ED₅₀for this effect is 0.04-0.2 ng/mL.
	Recombinant Human TGF-beta 1 Protein SDS-PAGE 1 μg/lane of Recombinant Human TGF-beta 1 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 12 kDa and 24 kDa, respectively.
	Recombinant Human TGF-beta 1 Protein Bioactivity Epithelial to Mesenchymal Transition (EMT) was induced in the A549 human lung carcinoma cell line with cell culture media supplemented with Recombinant Human (rh) TGF-beta 1 (Catalog # 240-B). Control cells were cultured without rhTGF-beta 1. EMT induction was confirmed at 48 h by flow cytometric staining for E-Cadherin (filled; Catalog # FAB18381P), an epithelial cell marker, or an isotype control (Catalog # IC0041P). TGF-beta 1 decreased the expression of E-Cadherin.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

240-B

Carrier

Formulation	Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution	Purified recombinant human TGF-beta 1 is an extremely hydrophobic protein that adheres strongly to surfaces. To ensure recovery, reconstitute at 20 μg/mL in sterile 4 mM HCl containing 1 mg/mL human or bovine serum albumin.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

240-B/CF

Carrier Free

Formulation	Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution	Reconstitute 2 µg vials at 20 µg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin. Reconstitute 10 µg or larger vials at 100 µg/mL in sterile 4 mM HCl.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: TGF-beta 1

TGF-beta 1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure (1‑7). TGF-beta 1, -2 and -3 are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition (1‑4). Each TGF-beta isoform has some non‑redundant functions; for TGF-beta 1, mice with targeted deletion show defects in hematopoiesis and endothelial differentiation, and die of overwhelming inflammation (2). Human TGF‑ beta 1 cDNA encodes a 390 amino acid (aa) precursor that contains a 29 aa signal peptide and a 361 aa proprotein (8). A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1 (8, 9). Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex (8‑10). Covalent linkage of LAP to one of three latent TGF‑ beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix (9, 10). TGF‑ beta is activated from latency by pathways that include actions of the protease plasmin, matrix metalloproteases, thrombospondin 1 and a subset of integrins (10). Mature human TGF‑ beta 1 shares 100% aa identity with pig, dog and cow TGF‑ beta 1, and 99% aa identity with mouse, rat and horse TGF‑ beta 1. It demonstrates cross‑species activity (1). TGF‑ beta 1 signaling begins with high‑affinity binding to a type II ser/thr kinase receptor termed TGF‑ beta RII. This receptor then phosphorylates and activates a second ser/thr kinase receptor, TGF‑ beta RI (also called activin receptor‑like kinase (ALK) ‑5), or alternatively, ALK‑1. This complex phosphorylates and activates Smad proteins that regulate transcription (3, 11, 12). Contributions of the accessory receptors betaglycan (also known as TGF‑ beta RIII) and endoglin, or use of Smad‑independent signaling pathways, allow for disparate actions observed in response to TGF‑ beta in different contexts (11).

Item	Value
References	Derynck, R. and K. Miyazono (2008) Cold Spring Harbor Laboratory Press, 29. Dunker, N. and K. Krieglstein (2000) Eur. J. Biochem. 267:6982. Wahl, S.M. (2006) Immunol. Rev. 213:213. Chang, H. et al. (2002) Endocr. Rev. 23:787. Lin, J.S. et al. (2006) Reproduction 132:179. Hinck, A.P. et al. (1996) Biochemistry 35:8517. Mittl, P.R.E. et al. (1996) Protein Sci. 5:1261. Derynck, R. et al. (1985) Nature 316:701. Miyazono, K. et al. (1988) J. Biol. Chem. 263:6407. Oklu, R. and R. Hesketh (2000) Biochem. J. 352:601. de Caestecker, M. et al. (2004) Cytokine Growth Factor Rev. 15:1. Zuniga, J.E. et al. (2005) J. Mol. Biol. 354:1052.
Long Name	Transforming Growth Factor beta 1
Entrez Gene IDs	7040 (Human); 21803 (Mouse); 59086 (Rat); 397078 (Porcine); 100033900 (Equine)
Alternate Names	CEDLAP, DPD1, TGF beta, TGF beta1, TGF-beta 1, TGF-beta 1 protein, TGF-beta-1, TGFB, TGFB1, TGFbeta, TGFbeta 1, latency-associated peptide, transforming growth factor beta-1, transforming growth factor, beta 1

Citations (671)

Showing 1 - 10 of 671 citations Showing All

Filter By:

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human TGF-beta 1 Protein include:

Species: Human
Sample Types: Whole Cells
Applications: Bioassay

G Du et al. (2020), Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo Cell Death Dis, 11(2):118.
PMID: 32051399
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

K Watanabe et al. (2020), Group V secreted phospholipase A2 plays a protective role against aortic dissection J. Biol. Chem., 295(30):10092-10111.
PMID: 32482892
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LK Senavirath et al. (2020), Hypoxia and transforming growth factor &beta1 regulation of long non-coding RNA transcriptomes in human pulmonary fibroblasts Physiol Rep, 8(1):e14343.
PMID: 31925944
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

QM Nhu et al. (2020), Antifibrotic Effects of the Thiazolidinediones in Eosinophilic Esophagitis Pathologic Remodeling: A Preclinical Evaluation Clin Transl Gastroenterol, 11(4):e00164.
PMID: 32352681
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Á Torres et al. (2020), Intraglomerular Monocyte/Macrophage Infiltration and Macrophage-Myofibroblast Transition during Diabetic Nephropathy Is Regulated by the A2B Adenosine Receptor Cells, 9(4):.
PMID: 32340145
DP Cook et al. (2020), Context specificity of the EMT transcriptional response Nat Commun, 11(1):2142.
PMID: 32358524
Species: Human
Sample Types: Whole Cells
Applications: Differentiation

SS Beauford et al. (2020), Ionizing radiation modulates the phenotype and function of human CD4+ induced regulatory T cells BMC Immunol., 21(1):18.
PMID: 32299365
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

YH Wang et al. (2020), Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-&kappaB Signaling Pathway in Hepatic Stellate Cells Front Pharmacol, 11(0):388.
PMID: 32296336
Species: Human
Sample Types: Whole Cells

M Liu et al. (2020), HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma Cancer Med, 0(0):.
PMID: 32281284
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IS Kang et al. (2020), Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation Sci Rep, 10(1):7024.
PMID: 32341385
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Hurrell et al. (2020), Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis Cells, 9(4):.
PMID: 32295224
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

R Xu et al. (2020), IL-35 is critical in suppressing superantigenic Staphylococcus aureus-driven inflammatory Th17 responses in human nasopharynx-associated lymphoid tissue Mucosal Immunol, 13(3):460-470.
PMID: 31896761
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AM Steitz et al. (2020), Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C Cell Death Dis, 11(4):249.
PMID: 32312959
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

N Ogasawara et al. (2020), Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps Mucosal Immunol, 13(1):86-95.
PMID: 31641233
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Lei et al. (2020), The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice Sci Rep, 10(1):7004.
PMID: 32332865
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MND Svensson et al. (2020), Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal Sci Adv, 6(26):eaba4353.
PMID: 32637608
Species: Rat
Sample Types: Whole Cell
Applications: Bioassay

C Zogbi et al. (2020), Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells Sci Rep, 10(1):12350.
PMID: 32704142
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

A Fujiwara et al. (2020), Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer Sci Rep, 10(1):10900.
PMID: 32616870
Species: Human
Sample Types: Cells
Applications: Cell Culture

R Fonseca et al. (2020), Developmental plasticity allows outside-in immune responses by resident memory T cells Nat. Immunol., 0(0):.
PMID: 32066954
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Ma et al. (2020), Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway Theranostics, 10(17):7730-7746.
PMID: 32685016
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

HY Seo et al. (2020), Src Inhibition Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation and Decreasing Connetive Tissue Growth Factor Cells, 9(3):.
PMID: 32120837
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Fan et al. (2020), Targeting the Notch and TGF-&beta signaling pathways to prevent retinal fibrosis in vitro and in vivo Theranostics, 10(18):7956-7973.
PMID: 32724452
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Krüger et al. (2019), Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair Int J Mol Sci, 20(17):.
PMID: 31480518
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Argemi et al. (2019), Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis Nat Commun, 10(1):3126.
PMID: 31311938
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

S Saraswati et al. (2019), Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing Nat Commun, 10(1):3027.
PMID: 31289275
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Sreekumar et al. (2019), Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC Cell Death Dis, 10(10):703.
PMID: 31543517
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Aoki et al. (2019), Sphingosine-1-Phosphate Facilitates Skin Wound Healing by Increasing Angiogenesis and Inflammatory Cell Recruitment with Less Scar Formation Int J Mol Sci, 20(14):.
PMID: 31295813
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Messerschm et al. (2019), Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation Mol. Vis., 25(0):329-344.
PMID: 31341381
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Pedroza et al. (2019), Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride PLoS ONE, 14(7):e0218971.
PMID: 31269038
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

DR Myers et al. (2019), Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells Cell Rep, 27(6):1858-1874.e6.
PMID: 31067469
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R van Dalen et al. (2019), Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses MBio, 10(3):.
PMID: 31088921
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Sakata et al. (2019), HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma Int J Mol Sci, 20(10):.
PMID: 31109142
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CJW Stock et al. (2019), Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation Biomed Res Int, 2019(0):1484736.
PMID: 31119153
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YH Lee et al. (2019), Effect of exposure to Asian sand dust-Particulate matter on liver Tenascin-C expression in human cancer cell and mouse hepatic tissue J Toxicol Sci, 44(9):633-641.
PMID: 31474744
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Du et al. (2019), Aurora A selective inhibitor LY3295668 leads to dominant mitotic arrest, apoptosis in cancer cells and shows potent preclinical antitumor efficacy Mol. Cancer Ther., 0(0):.
PMID: 31530649
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CL Hammond et al. (2019), Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor PLoS ONE, 14(9):e0222779.
PMID: 31536596
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

LP Garo et al. (2019), Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity Cell Rep, 28(13):3353-3366.e5.
PMID: 31553906
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DM Habiel et al. (2019), DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis BMC Pulm Med, 19(1):165.
PMID: 31464599
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Kamitani et al. (2019), Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease J. Dermatol. Sci., 0(0):.
PMID: 31570272
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Duan et al. (2019), Rational Reprogramming of Cellular States by Combinatorial Perturbation Cell Rep, 27(12):3486-3499.e6.
PMID: 31216470
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Berning et al. (2019), In vitro selective cytotoxicity of the dietary chalcone cardamonin (CD) on melanoma compared to healthy cells is mediated by apoptosis PLoS ONE, 14(9):e0222267.
PMID: 31553748
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Standard

N Kaushansky et al. (2019), Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms J. Immunol., 0(0):.
PMID: 31484731
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

S Granados-A et al. (2019), SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles Sci Rep, 9(1):6513.
PMID: 31015579
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YJ Choi et al. (2019), Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A Stem Cell Res Ther, 10(1):291.
PMID: 31547873
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Lv et al. (2019), MicroRNA?155 inhibits the proliferation of CD8+ Tï¿½cells via upregulating regulatory T cells in vitiligo Mol Med Rep, 20(4):3617-3624.
PMID: 31485649
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TTD Luong et al. (2019), Inhibition of vascular smooth muscle cell calcification by vasorin through interference with TGF Î²1 signaling Cell. Signal., 0(0):109414.
PMID: 31505229
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

M Bogdanova et al. (2019), Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties Sci Rep, 9(1):12934.
PMID: 31506459
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

P Diao et al. (2019), Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma J. Cell. Mol. Med., 0(0):.
PMID: 30950191
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Wang et al. (2019), TGF-?1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM EBioMedicine, 0(0):.
PMID: 30926424
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

F Peng et al. (2019), Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway Lab. Invest., 0(0):.
PMID: 30976056
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Derada Tro et al. (2019), Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology Cell Death Dis, 10(2):45.
PMID: 30718504
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

W Zheng et al. (2019), Integrated analysis of long non-coding RNAs and mRNAs associated with peritendinous fibrosis J Adv Res, 15(0):49-58.
PMID: 30581612
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Martin-Mat et al. (2019), Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-? Dependent Hepatic Stellate Cell Activation and Liver Fibrosis Cell Mol Gastroenterol Hepatol, 7(1):197-209.
PMID: 30539787
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Kijewska et al. (2019), Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain Breast Cancer Res., 21(1):4.
PMID: 30642388
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AG Kunihiro et al. (2019), Curcumin, but not curcumin-glucuronide, inhibits Smad signaling in TGF?-dependent bone metastatic breast cancer cells and is enriched in bone compared to other tissues J. Nutr. Biochem., 63(0):150-156.
PMID: 30393127
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B Wang et al. (2019), POH1 contributes to hyperactivation of TGF-? signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-? receptors and caveolin-1 EBioMedicine, 0(0):.
PMID: 30745168
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Zhang et al. (2019), TGFb1 suppresses the activation of distinct dNK subpopulations in preeclampsia EBioMedicine, 39(0):531-539.
PMID: 30579870
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BW Liu et al. (2019), Estrogen receptor-?-miR-1271-SNAI2 feedback loop regulates transforming growth factor-?-induced breast cancer progression J. Exp. Clin. Cancer Res., 38(1):109.
PMID: 30823890
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Gao et al. (2019), Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-?1 in bladder cancer cells J. Exp. Clin. Cancer Res., 38(1):111.
PMID: 30823924
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Yamashita et al. (2019), Increased expression of aquaporin-1 in dermal fibroblasts and dermal microvascular endothelial cells possibly contributes to skin fibrosis and edema in patients with systemic sclerosis J. Dermatol. Sci., 93(1):24-32.
PMID: 30270117
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SS Kim et al. (2019), Fibronectin synthesis, but not ?-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling Sci Rep, 9(1):2708.
PMID: 30804350
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JN Pucella et al. (2019), The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses J. Immunol., 0(0):.
PMID: 30683701
Species: Mouse
Sample Types: Spheroids
Applications: Bioassay

I Mannaerts et al. (2019), Unfolded protein response is an early, non-critical event during hepatic stellate cell activation Cell Death Dis, 10(2):98.
PMID: 30718473
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Higuchi et al. (2019), Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment Arthritis Res. Ther., 21(1):103.
PMID: 30999934
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RK Dutta et al. (2019), A Neutralizing Aptamer to TGFBR2 and miR-145 Antagonism Rescue Cigarette Smoke- and TGF-?-Mediated CFTR Expression Mol. Ther., 27(2):442-455.
PMID: 30595527
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Luo et al. (2019), Negligible Effect of Sodium Chloride on the Development and Function of TGF-?-Induced CD4+ Foxp3+ Regulatory T Cells Cell Rep, 26(7):1869-1879.e3.
PMID: 30759396
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

K Yasuda et al. (2019), Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation Nat Commun, 10(1):549.
PMID: 30710091
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

F Yao et al. (2019), ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription Lab. Invest., 0(0):.
PMID: 31641227
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Gramlich et al. (2019), In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists Int J Mol Sci, 20(6):.
PMID: 30893757
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Hochdörfer et al. (2019), Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells Eur. J. Immunol., 0(0):.
PMID: 30892687
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

YB Kim et al. (2019), Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis Cell. Mol. Immunol., 0(0):.
PMID: 30842627
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JS Park et al. (2019), Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma Nat Commun, 10(1):1128.
PMID: 30850660
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DQ Chen et al. (2019), Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan Nat Commun, 10(1):1476.
PMID: 30931940
Species: Human
Sample Types: Whole Cells

V Fleskens et al. (2019), Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells Cell Rep, 26(13):3600-3612.e6.
PMID: 30917315
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MR Hadjichara et al. (2019), Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis Sci Rep, 9(1):6020.
PMID: 30988425
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Zhou et al. (2019), Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC) EBioMedicine, 0(0):.
PMID: 31522982
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HC Lien et al. (2019), Fibrillin-1, a novel TGF-beta-induced factor, is preferentially expressed in metaplastic carcinoma with spindle sarcomatous metaplasia Pathology, 0(0):.
PMID: 31010590
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

JH Choi et al. (2019), Platyconic Acid A, Platycodi Radix-Derived Saponin, Suppresses TGF-1-induced Activation of Hepatic Stellate Cells via Blocking SMAD and Activating the PPAR Signaling Pathway Cells, 8(12):.
PMID: 31795488
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Li et al. (2019), Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells Redox Biol, 28(0):101373.
PMID: 31731100
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Bhatia et al. (2019), Mitophagy dependent macrophage reprogramming protects against kidney fibrosis JCI Insight, 0(0):.
PMID: 31639106
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Acheva et al. (2019), Presence of Stromal Cells Enhances Epithelial-to-Mesenchymal Transition (EMT) Induction in Lung Bronchial Epithelium after Protracted Exposure to Oxidative Stress of Gamma Radiation Oxid Med Cell Longev, 2019(0):4120379.
PMID: 31583039
Species: Human
Sample Types: Whole Cells
Applications: Tissue Culture

R Sachdeva et al. (2019), BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma Sci Rep, 9(1):14569.
PMID: 31602000
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

D Pham et al. (2019), Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf Cell Rep, 29(5):1203-1220.e7.
PMID: 31665634
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B Li et al. (2019), Clonorchis sinensis ESPs enhance the activation of hepatic stellate cells by a cross-talk of TLR4 and TGF-beta/Smads Signaling pathway Acta Trop., 0(0):105307.
PMID: 31862462
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YZ Huang et al. (2019), Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner Stem Cells Int, 2019(0):4242178.
PMID: 31885606
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Tochimoto et al. (2019), S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma Lab. Invest., 0(0):.
PMID: 31857700
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Huang et al. (2019), Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells Cancer Cell Int., 19(0):306.
PMID: 31832019
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Li et al. (2019), TGFbeta induces stemness through non-canonical AKT-FOXO3a axis in oral squamous cell carcinoma EBioMedicine, 0(0):.
PMID: 31629677
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P

N Uyama et al. (2019), Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation Sci Rep, 9(1):17558.
PMID: 31772282
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

M Krämer et al. (2019), Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system Cell. Signal., 65(0):109432.
PMID: 31693876
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

AW Horne et al. (2019), Repurposing dichloroacetate for the treatment of women with endometriosis Proc. Natl. Acad. Sci. U.S.A., 116(51):25389-25391.
PMID: 31792175
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

RW Scott et al. (2019), Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration Cell Stem Cell, 25(6):797-813.e9.
PMID: 31809738
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

L Andersen et al. (2019), The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells Cell Rep, 29(13):4447-4459.e6.
PMID: 31875552
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

E Foxall et al. (2019), PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells Cell Rep, 29(11):3385-3393.e6.
PMID: 31825823
Species: Human
Sample Types: Whole Cells
Applications: Stimulation

P Stylianou et al. (2019), Tensin1 expression and function in chronic obstructive pulmonary disease Sci Rep, 9(1):18942.
PMID: 31831813
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BS Ni et al. (2019), Plug-and-Play In Vitro Metastasis System toward Recapitulating the Metastatic Cascade Sci Rep, 9(1):18110.
PMID: 31792319
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YC Kim et al. (2019), ST2 blockade mitigates peritoneal fibrosis induced by TGF-beta and high glucose J. Cell. Mol. Med., 23(10):6872-6884.
PMID: 31397957
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

H Basma et al. (2019), TGF-beta induces a heart failure phenotype via fibroblasts exosome signaling Heliyon, 5(10):e02633.
PMID: 31687497
Species: Mink
Sample Types: Whole Cells
Applications: Bioassay

S Holvoet et al. (2019), Oral Tolerance Induction to Newly Introduced Allergen is Favored by a Transforming Growth Factor-beta-Enriched Formula Nutrients, 11(9):.
PMID: 31540231
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Yoo et al. (2019), Progranulin attenuates liver fibrosis by downregulating the inflammatory response Cell Death Dis, 10(10):758.
PMID: 31591383
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

V Welk et al. (2019), Proteasome activator PA200 regulates myofibroblast differentiation Sci Rep, 9(1):15224.
PMID: 31645612
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

W Chen et al. (2018), ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells Sci Rep, 8(1):16636.
PMID: 30413785
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Inoue et al. (2018), Arginine methylation controls the strength of ?c-family cytokine signaling in T cell maintenance Nat. Immunol., 19(11):1265-1276.
PMID: 30323341
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JT Chen et al. (2018), Curcumin inhibits TGF-?1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts J. Formos. Med. Assoc., 0(0):.
PMID: 29339038
Species: Fish
Sample Types: In Vivo
Applications: In Vivo

MR Conith et al. (2018), Genetic and developmental origins of a unique foraging adaptation in a Lake Malawi cichlid genus Proc. Natl. Acad. Sci. U.S.A., 0(0):.
PMID: 29915062
Species: Equine
Sample Types: Whole Cells
Applications: Bioassay

M Desancé et al. (2018), Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Int J Mol Sci, 19(2):.
PMID: 29439436
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CB Cummins et al. (2018), Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway Int J Mol Sci, 19(6):.
PMID: 29795016
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Hu et al. (2018), Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells Oncol Lett, 15(4):4867-4872.
PMID: 29552126
Applications: ELISA (Standard)

CC Tsai et al. (2018), Essential role of connective tissue growth factor (CTGF) in transforming growth factor-?1 (TGF-?1)-induced myofibroblast transdifferentiation from Graves' orbital fibroblasts Sci Rep, 8(1):7276.
PMID: 29739987
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Jiang et al. (2018), Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28 Nat Commun, 9(1):1424.
PMID: 29651155
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Liu et al. (2018), Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus JCI Insight, 3(23):.
PMID: 30518690
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BS Nepon-Sixt et al. (2018), TGFï¿½1 Cell Cycle Arrest Is Mediated by Inhibition of MCM Assembly in Rb-deficient Conditions Mol. Cancer Res., 0(0):.
PMID: 30257992
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

KB Kaylan et al. (2018), Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling Elife, 7(0):.
PMID: 30589410
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

P Mallikarju et al. (2018), VHL status regulates transforming growth factor-? signaling pathways in renal cell carcinoma Oncotarget, 9(23):16297-16310.
PMID: 29662646
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Fang et al. (2018), A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells Nat Commun, 9(1):4384.
PMID: 30349051
Species: Porcine
Sample Types: Plasma
Applications: Bioassay

T Huang et al. (2018), Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs Vet. Res., 49(1):121.
PMID: 30541630
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Beaulieu L et al. (2018), TGF-?1 promotes cell barrier function upon maturation of corneal endothelial cells Sci Rep, 8(1):4438.
PMID: 29535350
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PD Leiphrakpa et al. (2018), TGF? and IGF1R signaling activate protein kinase A through differential regulation of ezrin phosphorylation in colon cancerï¿½cells J. Biol. Chem., 0(0):.
PMID: 29599290
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Jia et al. (2018), The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/?-Catenin pathway Onco Targets Ther, 11(0):313-321.
PMID: 29391808
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Thome et al. (2018), Chloroquine-treated dendritic cells require STAT1 signaling for their tolerogenic activity Eur. J. Immunol., 0(0):.
PMID: 29572810
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

X Zhang et al. (2018), MicroRNA 483-3p targets Pard3 to potentiate TGF-?1-induced cell migration, invasion, and epithelial-mesenchymal transition in anaplastic thyroid cancer cells Oncogene, 0(0):.
PMID: 30171257
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Lin et al. (2018), FPPS mediates TGF-?1-induced non-small cell lung cancer cell invasion and the EMT process via the RhoA/Rock1 pathway Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29337059
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay

SJ Han et al. (2018), Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29337054
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Guo et al. (2018), D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion Stem Cells Int, 2018(0):7168231.
PMID: 30271438
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay

FC Bach et al. (2018), Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside Oncotarget, 9(41):26507-26526.
PMID: 29899873
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Amir et al. (2018), REV-ERB? Regulates TH17 Cell Development and Autoimmunity Cell Rep, 25(13):3733-3749.e8.
PMID: 30590045
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Wang et al. (2018), The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells Cell. Physiol. Biochem., 51(6):2547-2563.
PMID: 30562730
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Yang et al. (2018), Hydrogen sulfide promotes immunomodulation of gingiva-derived mesenchymal stem cells via the Fas/FasL coupling pathway Stem Cell Res Ther, 9(1):62.
PMID: 29523215
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Chen et al. (2018), Overexpression of LncRNA AC067945.2 Down-Regulates Collagen Expression in Skin Fibroblasts and Possibly Correlates with the VEGF and Wnt Signalling Pathways Cell. Physiol. Biochem., 45(2):761-771.
PMID: 29414824
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

JS Park et al. (2018), A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells Stem Cells, 0(0):.
PMID: 30444564
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Nowsheen et al. (2018), L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage Nat. Cell Biol., 20(4):455-464.
PMID: 29581593
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CC Weng et al. (2018), Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis Oncogene, 0(0):.
PMID: 30467381
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Nishida et al. (2018), Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-?-dependent and -independent mechanisms Oncogene, 0(0):.
PMID: 29391598
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YT Tang et al. (2018), Alterations in exosomal miRNA profile upon epithelial-mesenchymal transition in human lung cancer cell lines BMC Genomics, 19(1):802.
PMID: 30400814
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LR Penke et al. (2018), FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis J. Clin. Invest., 0(0):.
PMID: 29733296
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Nakayama et al. (2018), TGF?1-induced Amelotin gene expression is downregulated by Bax expression in mouse gingival epithelial cells J Oral Sci, 0(0):.
PMID: 29657250
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Park et al. (2018), Additive effect of bFGF and selenium on expansion and paracrine action of human amniotic fluid-derived mesenchymal stem cells Stem Cell Res Ther, 9(1):293.
PMID: 30409167
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MM Pleumeeker et al. (2018), Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture PLoS ONE, 13(2):e0190744.
PMID: 29489829
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Zila et al. (2018), Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases Clin Proteomics, 15(0):13.
PMID: 29541007
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Saxena et al. (2018), PyMT-1099, a versatile murine cell model for EMT in breast cancer Sci Rep, 8(1):12123.
PMID: 30108334
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KH Kim et al. (2018), A standardized herbal extract PM014 ameliorates pulmonary fibrosis by suppressing the TGF-?1 pathway Sci Rep, 8(1):16860.
PMID: 30443024
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YW Liao et al. (2018), miR-200b ameliorates myofibroblast transdifferentiation in precancerous oral submucous fibrosis through targeting ZEB2 J. Cell. Mol. Med., 0(0):.
PMID: 29893466
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Schmidt et al. (2018), Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3 BMC Biol., 16(1):47.
PMID: 29730990
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Dvornikov et al. (2018), Expression ratio of the TGF?-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response Sci Rep, 8(1):9517.
PMID: 29934580
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Zhang et al. (2018), DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway J. Immunol., 0(0):.
PMID: 29378913
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

F Das et al. (2018), Akt2 causes TGF?-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression PLoS ONE, 13(11):e0207285.
PMID: 30444896
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Životi? et al. (2018), Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells PLoS ONE, 13(11):e0206786.
PMID: 30383875
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Tiwary et al. (2018), Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a Sci Rep, 8(1):8267.
PMID: 29844613
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Wang et al. (2018), Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype Int J Mol Sci, 19(2):.
PMID: 29419805
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Schlereth et al. (2018), The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium Elife, 7(0):.
PMID: 29749927
Species: Rabbit
Sample Types: Whole Cells
Applications: Bioassay

X Feng et al. (2018), Injectable cartilaginous template transformed BMSCs into vascularized bone Sci Rep, 8(1):8244.
PMID: 29844536
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

YH Chung et al. (2018), BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-?1 signaling Lab. Invest., 0(0):.
PMID: 29789683
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Zhu et al. (2018), MicroRNA-212 activates hepatic stellate cells and promotes liver fibrosis via targeting SMAD7 Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29307832
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

J Choi et al. (2018), P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells Immunology, 0(0):.
PMID: 29297928
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Patalano et al. (2018), CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation Sci Rep, 8(1):3499.
PMID: 29472636
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Deng et al. (2018), TNFRSF19 inhibits TGF? signaling through interaction with TGF? receptor type I to promote tumorigenesis Cancer Res., 0(0):.
PMID: 29735548
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

F Ghodrati et al. (2018), The prion protein is embedded in a molecular environment that modulates transforming growth factor ? and integrin signaling Sci Rep, 8(1):8654.
PMID: 29872131
Species: Human
Sample Types: Complex Sample Type
Applications: Bioassay

G Zhou et al. (2018), In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction EBioMedicine, 28(0):287-302.
PMID: 29396297
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Ottaviani et al. (2018), TGF-? induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression Nat Commun, 9(1):1845.
PMID: 29748571
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Deshpande et al. (2018), Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy Sci Rep, 8(1):6954.
PMID: 29725042
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

R Zhang et al. (2018), RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke Cell Death Differ., 0(0):.
PMID: 29396549
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Qin et al. (2018), Actin cytoskeleton assembly regulates collagen production via TGF-? type II receptor in human skin fibroblasts J. Cell. Mol. Med., 0(0):.
PMID: 29888864
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Wang et al. (2018), Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling J. Cell. Mol. Med., 0(0):.
PMID: 29516637
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Z Al Shareef et al. (2018), Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 Oncogene, 0(0):.
PMID: 29858602
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Sugiura et al. (2018), Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model PLoS ONE, 13(3):e0191706.
PMID: 29518087
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Knüppel et al. (2018), FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis Respir. Res., 19(1):67.
PMID: 29673351
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Geng et al. (2018), MicroRNA-663 induces immune dysregulation by inhibiting TGF-?1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus Cell. Mol. Immunol., 0(0):.
PMID: 29578533
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Huang et al. (2018), CD8+ T cells with high TGF??1 expression cause lymph node fibrosis following HIV infection Mol Med Rep, 0(0):.
PMID: 29749506
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Park et al. (2018), Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation J Cancer Prev, 23(1):1-9.
PMID: 29629343
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

B Zhang et al. (2018), Hypoxia induces endothelial?mesenchymal transition in pulmonary vascular remodeling Int. J. Mol. Med., 0(0):.
PMID: 29568878
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Liu et al. (2018), Metformin ameliorates TGF-Î²1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting Î²-catenin signaling Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29679571
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Wu et al. (2018), Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis Mol. Hum. Reprod., 0(0):.
PMID: 29660008
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Murillo-Ga et al. (2018), Frizzled-8 integrates Wnt-11 and transforming growth factor-? signaling in prostate cancer Nat Commun, 9(1):1747.
PMID: 29717114
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

M Wang et al. (2018), Novel inhibitors of the cellular RAS components, Poricoic acids, target Smad3 phosphorylation and Wnt/Î²-catenin pathway against renal fibrosis Br. J. Pharmacol., 0(0):.
PMID: 29679507
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

S Lively et al. (2018), Comparing Effects of Transforming Growth Factor ?1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels Front Cell Neurosci, 12(0):115.
PMID: 29780305
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Standard

L Corsuto et al. (2018), Sulfation degree not origin of chondroitin sulfate derivatives modulates keratinocyte response Carbohydr Polym, 191(0):53-64.
PMID: 29661321
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Gupta et al. (2018), DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity Cell, 0(0):.
PMID: 29656893
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Groppa et al. (2018), EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF EMBO Rep., 0(0):.
PMID: 29643120
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Zaiatz-Bit et al. (2018), Canonical TGF-? Signaling Pathway Represses Human NK Cell Metabolism J. Immunol., 0(0):.
PMID: 29720425
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Imamura et al. (2018), RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase JCI Insight, 3(3):.
PMID: 29415885
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CF Hung et al. (2018), Role of integrin alpha8 in murine model of lung fibrosis PLoS ONE, 13(5):e0197937.
PMID: 29813125
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

RJ Marsh et al. (2018), Artifact-free high-density localization microscopy analysis Nat. Methods, 0(0):.
PMID: 30061677
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JM Dave et al. (2018), Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain Dev. Cell, 0(0):.
PMID: 29456135
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

O Kodet et al. (2018), Microenvironment?driven resistance to B?Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts Int. J. Mol. Med., 0(0):.
PMID: 29393387
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Löfdahl et al. (2018), Effects of 5-HT2receptor antagonists on bronchoconstriction and pulmonary remodeling processes Am. J. Pathol., 0(0):.
PMID: 29454752
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Merdrignac et al. (2018), A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma Hepatol Commun, 2(3):254-269.
PMID: 29507901
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Tian et al. (2018), Endoglin interacts with VEGFR2 to promote angiogenesis FASEB J., 0(0):fj201700867RR.
PMID: 29401587
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

L Gagnon et al. (2018), A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84 Am. J. Pathol., 0(0):.
PMID: 29454750
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Rekik et al. (2018), Impaired TGF-? signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22 Cytokine, 108(0):182-189.
PMID: 29684755
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

K Kobayashi et al. (2018), Role of monocyte chemoattractant protein-1 in liver fibrosis with transient myeloproliferative disorder in down syndrome Hepatol Commun, 2(3):230-236.
PMID: 29507898
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Wang et al. (2018), Identification of a TGF-?-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells FASEB J., 0(0):fj201701199R.
PMID: 29465312
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

T Rosengren et al. (2018), TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms Cell. Mol. Life Sci., 0(0):.
PMID: 29396625
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

M Losa et al. (2018), Face morphogenesis is promoted by Pbx-dependent EMT via regulation ofduring frontonasal prominence fusion Development, 0(0):.
PMID: 29437830
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

P Bozatzi et al. (2018), PAWS1 controls Wnt signalling through association with casein kinase 1? EMBO Rep., 0(0):.
PMID: 29514862
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay

S Liu et al. (2018), Ras enhances TGF-? signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1 Cell Commun. Signal, 16(1):10.
PMID: 29534718
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Fraser et al. (2018), A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials Mol Ther Methods Clin Dev, 8(0):198-209.
PMID: 29552576
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Kunita et al. (2018), MicroRNA-21 in cancer-associated fibroblasts supportsï¿½lung adenocarcinoma progression Sci Rep, 8(1):8838.
PMID: 29892003
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

T Yamakawa et al. (2018), Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease Blood, 0(0):.
PMID: 29363541
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

PS Bellaye et al. (2018), Synergistic role of HSP90? and HSP90? to promote myofibroblast persistence in lung fibrosis Eur. Respir. J., 51(2):.
PMID: 29386344
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

VNS Garikipati et al. (2018), Isolation and characterization of mesenchymal stem cells from human fetus heart PLoS ONE, 13(2):e0192244.
PMID: 29420637
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DJ Sharkey et al. (2018), Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 0(0):.
PMID: 29596569
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

SD Hardy et al. (2017), Regulation of epithelial-mesenchymal transition and metastasis by TGF-?, P-bodies, and autophagy Oncotarget, 8(61):103302-103314.
PMID: 29262563
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

W Shin et al. (2017), V-set and Ig domain-containing 4 (VSIG4)-expressing hepatic F4/80+ cells regulate oral antigen-specific responses in mouse Eur. J. Immunol., 0(0):.
PMID: 29235119
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KA Whelan et al. (2017), Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance Oncogene, 0(0):.
PMID: 28414310
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JB Koo et al. (2017), Anti-fibrogenic effect of PPAR-? agonists in human intestinal myofibroblasts BMC Gastroenterol, 17(1):73.
PMID: 28592228
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Siddiqui et al. (2017), Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells J. Pathol, 0(0):.
PMID: 28337746
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

H Hanieh et al. (2017), Arid5a stabilizes OX40 mRNA in murine CD4+ T cells by recognizing a stem-loop structure in its 3'UTR Eur. J. Immunol., 0(0):.
PMID: 29244194
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Kamata et al. (2017), KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis Sci Rep, 7(1):4556.
PMID: 28676645
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Pan et al. (2017), Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis Scand. J. Immunol., 0(0):.
PMID: 28376277
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

N Salvarani et al. (2017), TGF-?1 (Transforming Growth Factor-?1) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity Circ Arrhythm Electrophysiol, 10(5):e004567.
PMID: 28500173
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Qi et al. (2017), Transforming growth factor-?1 signaling promotes epithelial-mesenchymal transition-like phenomena, cell motility, and cell invasion in synovial sarcoma cells PLoS ONE, 12(8):e0182680.
PMID: 28829837
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

SZ Wu et al. (2017), Dual roles of parathyroid hormone-related protein in TGF-?1 signaling and fibronectin upregulation in mesangial cells Biosci. Rep., 0(0):.
PMID: 28954822
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Yu et al. (2017), Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2 Cell. Physiol. Biochem., 43(6):2242-2252.
PMID: 29073595
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

W Zhao et al. (2017), Cdk5 is required for the neuroprotective effect of transforming growth factor-?1 against cerebral ischemia-reperfusion Biochem. Biophys. Res. Commun, 0(0):.
PMID: 28254431
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Zhang (2017), Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/?-catenin signaling Biochem. Biophys. Res. Commun., 0(0):.
PMID: 28427938
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EM Reyes-Reye et al. (2017), LINE-1 couples EMT programming with acquisition of oncogenic phenotypes in human bronchial epithelial cells Oncotarget, 8(61):103828-103842.
PMID: 29262603
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JJ Kathiriya et al. (2017), Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis Cell Death Discov, 3(0):17010.
PMID: 28417017
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Iizuka et al. (2017), Hydrogen Peroxide Enhances TGF?-mediated Epithelial-to-Mesenchymal Transition in Human Mammary Epithelial MCF-10A Cells Anticancer Res, 37(3):987-995.
PMID: 28314256
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Saito et al. (2017), Tubastatin ameliorates pulmonary fibrosis by targeting the TGF?-PI3K-Akt pathway PLoS ONE, 12(10):e0186615.
PMID: 29045477
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

YL Li et al. (2017), GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway Oncotarget, 8(1):1508-1528.
PMID: 27903972
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Dimitrova et al. (2017), TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition Biol. Direct, 12(1):8.
PMID: 28412966
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DW Hammers et al. (2017), Supraphysiological levels of GDF11 induce striated muscle atrophy EMBO Mol Med, 0(0):.
PMID: 28270449
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

T Ruetz et al. (2017), Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming Cell Stem Cell, 0(0):.
PMID: 29174331
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Zhou et al. (2017), Cytidine monophosphate kinase is inhibited by the TGF-? signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer Cell. Signal., 0(0):.
PMID: 28414100
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SK Sahu et al. (2017), FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development Nat Commun, 8(1):1523.
PMID: 29142217
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C Caër et al. (2017), Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue Sci Rep, 7(1):3000.
PMID: 28592801
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

G Mondanelli et al. (2017), A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells Immunity, 46(2):233-244.
PMID: 28214225
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Desai et al. (2017), HR+HER2- breast cancers with growth factor receptor-mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells Tumour Biol, 39(3):1010428317695.
PMID: 28349782
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Y Tachida et al. (2017), Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells Biol Open, 6(3):370-380.
PMID: 28298363
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay

BA Boswell et al. (2017), Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract Mol. Biol. Cell, 0(0):.
PMID: 28209733
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EJ Kim et al. (2017), Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties Clin Orthop Surg, 9(2):239-248.
PMID: 28567229
S Lee et al. (2017), Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production Cell. Physiol. Biochem., 42(4):1684-1700.
PMID: 28743125
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JC Cheng et al. (2017), TGF-?1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation Cell. Signal., 43(0):55-61.
PMID: 29269046
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ZM Zhao et al. (2017), Levistilide A inhibits angiogenesis in liver fibrosis via vascular endothelial growth factor signaling pathway Exp. Biol. Med. (Maywood), 242(9):974-985.
PMID: 28440736
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Y Hu et al. (2017), Armc5 deletion causes developmental defects and compromises T-cell immune responses Nat Commun, 8(0):13834.
PMID: 28169274
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TP Nguyen et al. (2017), TGF-? inhibits IL-7-induced proliferation in memory but not naive human CD4(+) T cells J. Leukoc. Biol., 0(0):.
PMID: 28588029
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Calvier et al. (2017), PPAR? Links BMP2 and TGF?1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism Cell Metab., 25(5):1118-1134.e7.
PMID: 28467929
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Pap et al. (2017), Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammation and Tissue Remodeling Kidney Blood Press. Res, 42(1):16-32.
PMID: 28253513
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Ghatak et al. (2017), TGF beta-1 induced CD44v6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis J. Biol. Chem., 0(0):.
PMID: 28389561
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C Pagiatakis et al. (2017), TGF?-TAZ/SRF Signaling regulates vascular smooth muscle cell differentiation FEBS J, 0(0):.
PMID: 28342289
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay

K Sakaguchi et al. (2017), Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells Biochem. Biophys. Res. Commun, 484(1):100-106.
PMID: 28104393
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Ko et al. (2017), Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy Invest. Ophthalmol. Vis. Sci., 58(5):2544-2553.
PMID: 28492873
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Shiokawa et al. (2017), Mesenteric lymph node CD11b(-) CD103(+) PD-L1(High) dendritic cells highly induce regulatory T cells Immunology, 0(0):.
PMID: 28423181
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Q Zhao et al. (2017), Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota J. Immunol., 0(0):.
PMID: 28539431
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

L Bai et al. (2017), SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells Cell. Signal., 37(0):52-61.
PMID: 28578012
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MA L‚cuyer et al. (2017), Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis Proc. Natl. Acad. Sci. U.S.A, 114(4):E524-E533.
PMID: 28069965
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

F Loayza-Puc et al. (2017), TGF?1-induced leucine limitation uncovered by differential ribosome codon reading EMBO Rep, 0(0):.
PMID: 28274951
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JC Cheng et al. (2017), Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes Sci Rep, 7(1):4448.
PMID: 28667290
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

S Khakipoor et al. (2017), TGF-? signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes Glia, 0(0):.
PMID: 28568893
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KB McCauley et al. (2017), Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling Cell Stem Cell, 0(0):.
PMID: 28366587
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

P Åström et al. (2017), The interplay of matrix metalloproteinase-8, transforming growth factor-?1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma Br. J. Cancer, 117(7):1007-1016.
PMID: 28772283
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ying Chen et al. (2017), MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. British Journal of Cancer, 0(0):1532-1827.
PMID: 28817834
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Kamio et al. (2017), XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts Pulm Pharmacol Ther, 0(0):.
PMID: 28315487
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Kusumoto et al. (2017), Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma Cancer Sci., 108(3):528-535.
PMID: 28004467
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chris J C Johnston et al. (2017), A structurally distinct TGF-? mimic from an intestinal helminth parasite potently induces regulatory T cells. Nature Communications, 0(0):2041-1723.
PMID: 29170498
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

J Geng et al. (2017), The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells Nat. Immunol., 0(0):.
PMID: 28504697
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Shibata et al. (2017), Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy PLoS ONE, 12(10):e0186587.
PMID: 29065190
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nisha Bte Mohd Rafiq (2017), Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO J. Cell Biol, 216(1):181-197.
PMID: 28007915
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tsugumi Horikiri (2017), Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia Respir Med, 122(0):43-50.
PMID: 27993290
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

R Singh et al. (2017), Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells J. Immunol., 0(0):.
PMID: 28455436
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

KH Bae et al. (2017), Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor ? Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice Endocrinol Metab (Seoul), 0(0):.
PMID: 28256116
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

V Ruiz-Carpi et al. (2017), Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients Sci Rep, 7(0):44941.
PMID: 28327551
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Renard et al. (2017), Sex, pregnancy and aortic disease in Marfan syndrome PLoS ONE, 12(7):e0181166.
PMID: 28708846
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

W Wang et al. (2017), Osteopontin activates mesenchymal stem cells to repair skin wound PLoS ONE, 12(9):e0185346.
PMID: 28957406
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Sasahara et al. (2017), An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells Oncotarget, 8(15):24869-24881.
PMID: 28206960
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Brethour et al. (2017), A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition Sci Rep, 7(0):40313.
PMID: 28098160
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Shyam Kumar Gudey et al. (2017), Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGF? stimulation in cancer. Oncotarget, 0(0):1949-2553.
PMID: 29228645
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Turcotte et al. (2017), CD73 promotes resistance to HER2/ErbB2 antibody therapy Cancer Res., 0(0):.
PMID: 28855210
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Sato-Matsu et al. (2017), Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling J. Biol. Chem., 0(0):.
PMID: 28916723
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Gopal et al. (2017), Fibronectin-guided migration of carcinoma collectives Nat Commun, 8(0):14105.
PMID: 28102238
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

VC Rodríguez- et al. (2017), Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites Sci Rep, 7(1):7594.
PMID: 28790320
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Rynne-Vida et al. (2017), Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer J. Pathol, 0(0):.
PMID: 28247413
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Gamboa Cas et al. (2016), Clustering and jamming in epithelial-mesenchymal co-cultures Soft Matter, 12(40):8327-8337.
PMID: 27722738
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hoeke A Baarsma (2016), Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD J. Exp. Med, 0(0):.
PMID: 27979969
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mohadeseh Mehrabian (2016), Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue PLoS ONE, 11(6):e0156779.
PMID: 27327609
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Martine Schrøder (2016), CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits PLoS ONE, 11(6):e0157387.
PMID: 27311059
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT Nat Commun, 7(0):13362.
PMID: 27869122
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MH Fan et al. (2016), Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice J. Biol. Chem., 291(15):8070-89.
PMID: 26663085
(2016), Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci Nat Commun, 7(0):12092.
PMID: 27386823
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Karthikeyan Mythreye (2016), Altering the Proteoglycan State of Transforming Growth Factor ? Type III Receptor (T?RIII)/Betaglycan Modulates Canonical Wnt/?-Catenin Signaling J. Biol. Chem., 291(49):25716-25728.
PMID: 27784788
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Brian G Oliver (2016), A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro Thorax, 71(11):1039-1049.
PMID: 27287090
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Fscn1 is required for the trafficking of TGF-? family type I receptors during endoderm formation Nat Commun, 7(0):12603.
PMID: 27545838
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases Cell Death Dis, 7(12):e2565.
PMID: 28032864
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M F Griffin (2016), Chemical group-dependent plasma polymerisation preferentially directs adipose stem cell differentiation towards osteogenic or chondrogenic lineages Acta Biomater, 0(0):.
PMID: 27956359
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves EBioMedicine, 10(0):282-90.
PMID: 27394642
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Takeshi Suzuki (2016), MEG3 long noncoding RNA contributes to the epigenetic regulation of epithelial-mesenchymal transition in lung cancer cell lines J. Biol. Chem., 0(0):.
PMID: 27852821
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching Sci Rep, 6(0):37215.
PMID: 27853268
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Qisheng Li (2016), Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition Proc Natl Acad Sci USA, 0(0):.
PMID: 27298373
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-?1 in Airway Epithelium PLoS ONE, 11(8):e0162058.
PMID: 27571418
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Claire Yu (2016), Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion Biomaterials, 120(0):66-80.
PMID: 28038353
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), MAP3K19 Is a Novel Regulator of TGF-? Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis PLoS ONE, 11(5):e0154874.
PMID: 27144281
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sasaki C et al. (2016), p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice. Eur J Immunol, 46(1):212-22.
PMID: 26514620
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

James B Canavan (2016), Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease Gut, 65(4):584-94.
PMID: 25715355
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis Physiol Rep, 4(17):.
PMID: 27582065
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bharat Vaidyanath (2016), The aryl hydrocarbon receptor controls cell-fate decisions in B cells J. Exp. Med, 0(0):.
PMID: 28011866
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-? Small Molecule Inhibitor Neoplasia, 18(12):795-805.
PMID: 27978994
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis Sci Rep, 6(0):37445.
PMID: 27869174
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Shoko Ohno (2016), Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure Sci Rep, 6(0):27192.
PMID: 27273361
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dong-Chuan Guo (2016), Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease Am. J. Hum. Genet, 0(0):.
PMID: 27939641
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Transient RUNX1 Expression during Early Mesendodermal Differentiation ofï¿½hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling Stem Cell Reports, 7(5):884-896.
PMID: 27720906
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Flynn et al. (2016), Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism Blood, 127(17):2144-54.
PMID: 26983850
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells Cancer Res, 0(0):.
PMID: 27221703
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

(2016), 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats PLoS ONE, 11(8):e0161782.
PMID: 27575371
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xiuyun Zeng (2016), TAR DNA-binding protein 43 inhibits inflammatory response and protects chondrocyte function by modulating RACK1 expression in osteoarthritis Biomed. Pharmacother., 0(0):.
PMID: 27890430
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), IL-10 production in murine IgM(+) CD138(hi) cells is driven by Blimp1 and downregulated in class-switched cells Eur. J. Immunol, 0(0):.
PMID: 28012163
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Isabela Pedroza-Pa et al. (2016), Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Scientific Reports, 0(0):2045-2322.
PMID: 26915707
Species: Human
Sample Types: Protein
Applications: ELISA (Standard)

(2016), Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes Stem Cell Reports, 0(0):.
PMID: 27569062
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Menq-Jer Lee (2016), TGF-?/ SMAD3 Pathway Stimulates Sphingosine-1-phosphate Receptor 3 Expression: Implication of Sphingosine-1-Phosphate Receptor 3 in Lung Adenocarcinoma Progression J. Biol. Chem., 0(0):.
PMID: 27856637
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Miyashita et al. (2016), Immunotherapy against Metastatic Melanoma with Human iPS Cell-Derived Myeloid Cell Lines Producing Type I Interferons Cancer Immunol Res, 4(3):248-58.
PMID: 26714554
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Context-Specific Function of S6K2 in Th Cell Differentiation J Immunol, 0(0):.
PMID: 27613697
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

(2016), Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin Sci Rep, 6(0):36436.
PMID: 27819314
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Cell-cell contact and matrix adhesion promote ?SMA expression during TGF?1-induced epithelial-myofibroblast transition via Notch and MRTF-A Sci Rep, 6(0):26226.
PMID: 27194451
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Saverio Bellusci (2016), Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis Cell Stem Cell, 0(0):.
PMID: 27867035
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2016), Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas PLoS ONE, 11(12):e0167200.
PMID: 28030558
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016), Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Clin Cancer Res, 0(0):.
PMID: 27126993
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ilkow C et al. (2015), Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med, 21(5):530-6.
PMID: 25894825
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Harris T et al. (2015), Drak2 Does Not Regulate TGF-beta Signaling in T Cells. PLoS ONE, 10(5):e0123650.
PMID: 25951457
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kinugasa H et al. (2015), Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene, 34(41):5229-39.
PMID: 25659582
Species: Equine
Sample Types: Plasma

Giraldo C et al. (2015), Effects of sodium citrate and acid citrate dextrose solutions on cell counts and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel. BMC Vet Res, 11(0):60.
PMID: 25889052
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Roach K et al. (2015), Lipoxin A4 Attenuates Constitutive and TGF-beta1-Dependent Profibrotic Activity in Human Lung Myofibroblasts. J Immunol, 195(6):2852-60.
PMID: 26276873
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Narcisi R et al. (2015), Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. Stem Cell Reports, 4(3):459-72.
PMID: 25733021
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)

Kaushansky N et al. (2015), Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease. J Biol Chem, 290(24):15260-78.
PMID: 25911099
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Pessina P et al. (2015), Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skelet Muscle, 4(0):7.
PMID: 25157321
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mehrabian M et al. (2015), The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE, 10(8):e0133741.
PMID: 26288071
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Young K et al. (2015), BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS ONE, 10(4):e0122892.
PMID: 25909848
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Schmitt-Ney M et al. (2015), The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-beta pathway. PLoS ONE, 10(3):e0121474.
PMID: 25806826
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lu G et al. (2015), Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A, 113(5):1256-60.
PMID: 26787905
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sahu S et al. (2015), JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J, 34(16):2162-81.
PMID: 26157010
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wang J et al. (2015), Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development. Cancer Res, 75(2):306-15.
PMID: 25492861
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Presnell S et al. (2015), Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs. Genes Immun, 16(1):89-98.
PMID: 25410655
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nguyen L et al. (2015), Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat Immunol, 16(2):207-13.
PMID: 25531831
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nakatsukasa H et al. (2015), The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol, 16(10):1077-84.
PMID: 26322481
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2015), MiR-133 modulates TGF-ÃŽÂ²1-induced bladder smooth muscle cell hypertrophic and fibrotic response: implication for a role of microRNA in bladder wall remodeling caused by bladder outlet obstruction. Cell Signal, 27(2):215-27.
PMID: 25451078
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rutz S et al. (2015), Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature, 518(7539):417-21.
PMID: 25470037
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lian M et al. (2015), Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-gamma Expression. PLoS ONE, 10(7):e0132741.
PMID: 26177196
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pang M et al. (2015), TGF-beta1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene, 35(6):748-60.
PMID: 25961925
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Yu D et al. (2015), The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway. Acta Pharmacol Sin, 36(4):473-82.
PMID: 25832428
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Jia D et al. (2015), Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE, 10(3):e0121939.
PMID: 25822822
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Klimatcheva E et al. (2015), CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol, 16(0):6.
PMID: 25879435
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Eun S et al. (2015), 4-1BB ligand signaling to T cells limits T cell activation. J Immunol, 194(1):134-41.
PMID: 25404362
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Masani S et al. (2015), Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination. Proc Natl Acad Sci U S A, 113(5):1261-6.
PMID: 26787901
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sugita S et al. (2015), Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 56(2):1051-62.
PMID: 25604685
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cho W et al. (2015), Suppressor of cytokine signaling 1 is a positive regulator of TGF-beta-induced prostaglandin production in human follicular dendritic cell-like cells. J Immunol, 194(9):4287-97.
PMID: 25825445
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Woltje K et al. (2015), Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells. PLoS ONE, 10(3):e0120547.
PMID: 25799559
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rojas-Fernandez A et al. (2015), Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep, 5(0):9811.
PMID: 25922883
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Woeller C et al. (2015), Salinomycin and other polyether ionophores are a new class of antiscarring agent. J Biol Chem, 290(6):3563-75.
PMID: 25538236
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Waight J et al. (2015), Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans. J Immunol, 194(3):878-82.
PMID: 25548231
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sun et al. (2015), Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J Immunol Res, 2015(0):284215.
PMID: 25918734
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Galvagni F et al. (2015), Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells, 33(3):742-50.
PMID: 25504116
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kuk H et al. (2015), 5Z-7-Oxozeanol Inhibits the Effects of TGFbeta1 on Human Gingival Fibroblasts. PLoS ONE, 10(4):e0123689.
PMID: 25927238
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Singh I et al. (2015), High mobility group protein-mediated transcription requires DNA damage marker gamma-H2AX. Cell Res, 25(7):837-50.
PMID: 26045162
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mu Y et al. (2015), TGFbeta-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells. Br J Cancer, 112(7):1223-31.
PMID: 25756394
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fujita T et al. (2015), Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PLoS ONE, 10(6):e0130808.
PMID: 26110809
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cruet-Hennequart S et al. (2015), Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE, 10(3):e0119334.
PMID: 25837977
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ghiabi P et al. (2015), Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med, 13(0):27.
PMID: 25623554
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Miller C et al. (2014), Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet, 10(3):e1004263.
PMID: 24676100
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pan C et al. (2014), Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. J Biol Chem, 289(37):25486-96.
PMID: 25070888
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Haffner-Luntzer et al. (2014), Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice. PLoS ONE, 9(12):e116282.
PMID: 25551381
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wu Y et al. (2014), COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer. Oncogene, 33(26):3432-40.
PMID: 23934190
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Chen K et al. (2014), The AMPK agonist AICAR inhibits TGF-beta1 induced activation of kidney myofibroblasts. PLoS ONE, 9(9):e106554.
PMID: 25188319
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xu S et al. (2014), Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-beta and induce Tregs development via TGF-beta. PLoS ONE, 9(3):e91709.
PMID: 24638085
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Yu Y et al. (2014), Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation. Mol Med Rep, 9(6):2077-84.
PMID: 24682227
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ueda J et al. (2014), Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene, 33(36):4485-95.
PMID: 24077287
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Togashi et al. (2014), Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer. Mol Cancer, 13(0):126.
PMID: 24886203
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Salvo E et al. (2014), Combined targeting of TGF-beta1 and integrin beta3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer. Mol Cancer, 13(0):112.
PMID: 24884715
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Midgley A et al. (2014), MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell, 13(2):235-44.
PMID: 24134702
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Liu R et al. (2014), JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol, 44(5):1643-51.
PMID: 24573038
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Li J et al. (2014), The anti-proliferative function of the TGF-beta1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3. J Biol Chem, 289(51):35633-43.
PMID: 25371204
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Zhou Y et al. (2014), Secreted fibroblast-derived miR-34a induces tubular cell apoptosis in fibrotic kidney. J Cell Sci, 127(0):4494-506.
PMID: 25107369
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Karki S et al. (2014), Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis. FASEB J, 28(3):1122-31.
PMID: 24265486
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yao G et al. (2014), MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3. Mol Cell Endocrinol, 382(1):244-53.
PMID: 24145127
Species: Human
Sample Types: Whole Cells

Kofler D et al. (2014), Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J Clin Invest, 124(6):2513-22.
PMID: 24812667
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suresh Babu S et al. (2014), TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer, 14(0):113.
PMID: 24555435
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Han L et al. (2014), The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor gammat (RORgammat) in Th17 cells. J Biol Chem, 289(37):25546-55.
PMID: 25070893
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kumawat K et al. (2014), TGF-beta-activated kinase 1 (TAK1) signaling regulates TGF-beta-induced WNT-5A expression in airway smooth muscle cells via Sp1 and beta-catenin. PLoS ONE, 9(4):e94801.
PMID: 24728340
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Choi S et al. (2014), Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. J Clin Invest, 124(6):2472-82.
PMID: 24837432
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bohnsack R et al. (2014), Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. Invest Ophthalmol Vis Sci, 55(12):7697-708.
PMID: 25358730
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Zheng J et al. (2014), Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis. FEBS J, 281(1):88-103.
PMID: 24138392
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Normanton M et al. (2014), Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE, 9(9):e106673.
PMID: 25184791
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Baldwin A et al. (2014), Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. J Cell Sci, 127(0):158-71.
PMID: 24190885
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tobar N et al. (2014), c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer, 14(0):640.
PMID: 25175743
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chen X et al. (2014), Effective chemoimmunotherapy with anti-TGFbeta antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE, 9(1):e85398.
PMID: 24416401
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mercer F et al. (2014), Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors. J Immunol, 193(3):1047-54.
PMID: 24958901
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Qu X et al. (2014), A signal transduction pathway from TGF-beta1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma. J Invest Dermatol, 134(1):159-67.
PMID: 23792459
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fehrholz M et al. (2014), Caffeine and rolipram affect Smad signalling and TGF-beta1 stimulated CTGF and transgelin expression in lung epithelial cells. PLoS ONE, 9(5):e97357.
PMID: 24828686
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kuang D et al. (2014), B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest, 124(10):4657-67.
PMID: 25244097
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Okada Y et al. (2014), TRPA1 is required for TGF-beta signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma. Lab Invest, 94(9):1030-41.
PMID: 25068659
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jakobsen R et al. (2014), Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE, 9(5):e96615.
PMID: 24816923
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chen L et al. (2014), Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines. PLoS ONE, 9(7):e101040.
PMID: 24983967
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Prigent L et al. (2014), The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation. Eur J Immunol, 44(5):1330-40.
PMID: 24549985
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rojo J et al. (2014), Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo. J Leukoc Biol, 95(3):441-50.
PMID: 24212096
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ratnayake M et al. (2014), Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE, 9(1):e86590.
PMID: 24466161
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kongsbak M et al. (2014), Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE, 9(5):e96695.
PMID: 24792400
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Komatsu N et al. (2014), Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med, 20(1):62-8.
PMID: 24362934
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Shi X et al. (2014), TGF-beta/Smad3 stimulates stem cell/developmental gene expression and vascular smooth muscle cell de-differentiation. , 9(0):.
PMID: 24718260
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Kim D et al. (2014), Gene expression profiles of human adipose tissue-derived mesenchymal stem cells are modified by cell culture density. PLoS ONE, 9(1):e83363.
PMID: 24400072
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Luo F et al. (2014), Arsenic trioxide inhibits transforming growth factor-beta1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. Respir Res, 15(0):51.
PMID: 24762191
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Xiao et al. (2014), Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE, 9(9):e106538.
PMID: 25198549
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kirkegaard T et al. (2014), The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines. Int J Oncol, 45(1):393-400.
PMID: 24819550
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Olderoy M et al. (2014), Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels. PLoS ONE, 9(3):e91662.
PMID: 24626259
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gordian E et al. (2014), Transforming growth factor beta signaling overcomes dasatinib resistance in lung cancer. PLoS ONE, 9(12):e114131.
PMID: 25501935
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Schwartze J et al. (2014), Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-beta signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts. J Biol Chem, 289(6):3262-75.
PMID: 24347165
Overstreet J et al. (2014), Redox control of p53 in the transcriptional regulation of TGF-beta1 target genes through SMAD cooperativity. Cell Signal, 26(7):1427-36.
PMID: 24613410
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rozycki M et al. (2014), The fate of the primary cilium during myofibroblast transition. Mol Biol Cell, 25(5):643-57.
PMID: 24403605
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wei D et al. (2014), Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing. PLoS Pathog, 10(4):e1004071.
PMID: 24722454
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Liu Y et al. (2014), Inhibition by all-trans-retinoic acid of transforming growth factor-beta-induced collagen gel contraction mediated by human tenon fibroblasts. Invest Ophthalmol Vis Sci, 55(7):4199-205.
PMID: 24894398
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gallo E et al. (2014), Angiotensin II-dependent TGF-beta signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest, 124(1):448-60.
PMID: 24355923
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Matsuhashi S et al. (2014), Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells. Cell Signal, 26(3):603-10.
PMID: 24334270
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hardin H et al. (2014), The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. Am J Pathol, 184(8):2342-54.
PMID: 24946010
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Neumann C et al. (2014), Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med, 211(9):1807-19.
PMID: 25073792
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zafar A et al. (2014), Chromatinized protein kinase C-theta directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Mol Cell Biol, 34(16):2961-80.
PMID: 24891615
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Chen C et al. (2014), Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol Med, 6(3):322-34.
PMID: 24401839
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tulley S et al. (2014), Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-beta signaling. J Biol Chem, 289(22):15280-96.
PMID: 24727589
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hou S et al. (2014), Follicular dendritic cell secreted protein FDC-SP controls IgA production. Mucosal Immunol, 7(4):948-57.
PMID: 24399151
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay

Miller M et al. (2014), CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGFbeta / GARP-mediated mechanism. Virol J, 11(0):7.
PMID: 24438223
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wang X et al. (2014), Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF-beta signaling pathway. Int J Oncol, 44(4):1099-106.
PMID: 24452274
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Solomon J et al. (2014), VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol Cancer Res, 12(8):1166-80.
PMID: 24825850
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Arts M et al. (2014), Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor. PLoS ONE, 9(6):e100035.
PMID: 24927197
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Acuna M et al. (2014), Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-beta signalling. Hum Mol Genet, 23(5):1237-49.
PMID: 24163134
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gobel K et al. (2014), Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. Eur J Immunol, 44(8):2295-305.
PMID: 24811005
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Desai L et al. (2014), Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein. J Biol Chem, 289(26):18270-8.
PMID: 24831009
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lim M et al. (2014), Induction of galectin-1 by TGF-beta1 accelerates fibrosis through enhancing nuclear retention of Smad2. Exp Cell Res, 326(1):125-35.
PMID: 24928277
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Diepenbruck et al. (2014), Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition. J Cell Sci, 127(0):1523-36.
PMID: 24554433
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gao X et al. (2014), Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS ONE, 9(2):e89114.
PMID: 24586530
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jolly L et al. (2014), Influenza promotes collagen deposition via alphavbeta6 integrin-mediated transforming growth factor beta activation. J Biol Chem, 289(51):35246-63.
PMID: 25339175
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Brady K et al. (2014), Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 23(5):541-54.
PMID: 24172175
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Axpe E et al. (2014), Detection of atomic scale changes in the free volume void size of three-dimensional colorectal cancer cell culture using positron annihilation lifetime spectroscopy. PLoS ONE, 9(1):e83838.
PMID: 24392097
Species: Feline
Sample Types: Whole Cells
Applications: Bioassay

Jeon K et al. (2014), Inhibitory effects of PPARgamma ligands on TGF-beta1-induced corneal myofibroblast transformation. Am J Pathol, 184(5):1429-45.
PMID: 24650561
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Aschner Y et al. (2014), Protein tyrosine phosphatase alpha mediates profibrotic signaling in lung fibroblasts through TGF-beta responsiveness. Am J Pathol, 184(5):1489-502.
PMID: 24650563
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Matthews A et al. (2014), Binding of AID to DNA does not correlate with mutator activity. J Immunol, 193(1):252-7.
PMID: 24879790
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cheng T et al. (2014), Transforming growth factor-beta-induced miR143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo. Int J Oncol, 45(5):1977-88.
PMID: 25175415
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kudo-Saito C et al. (2014), Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Res, 74(5):1361-70.
PMID: 24590808
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Park S et al. (2014), Musashi-2 controls cell fate, lineage bias, and TGF-beta signaling in HSCs. J Exp Med, 211(1):71-87.
PMID: 24395885
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Li H et al. (2014), Independent adipogenic and contractile properties of fibroblasts in Graves' orbitopathy: an in vitro model for the evaluation of treatments. PLoS ONE, 9(4):e95586.
PMID: 24751986
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Santhekadur P et al. (2014), Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling. FEBS Open Bio, 4(0):353-61.
PMID: 24918049
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Italiani et al. (2014), Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS ONE, 9(2):e87680.
PMID: 24498352
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Okabe H et al. (2014), Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma. PLoS ONE, 9(6):e98817.
PMID: 24892551
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mael-Ainin M et al. (2014), Inhibition of periostin expression protects against the development of renal inflammation and fibrosis. J Am Soc Nephrol, 25(8):1724-36.
PMID: 24578131
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Loureiro J et al. (2013), Tamoxifen ameliorates peritoneal membrane damage by blocking mesothelial to mesenchymal transition in peritoneal dialysis. PLoS ONE, 8(4):e61165.
PMID: 23637793
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Yasmin N et al. (2013), Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J Exp Med, 210(12):2597-610.
PMID: 24190429
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Wang X et al. (2013), TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses. J Immunol, 191(11):5420-9.
PMID: 24140642
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cheng J et al. (2013), Transforming growth factor-beta1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein. J Biol Chem, 288(46):33181-92.
PMID: 24106276
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Truchetet M et al. (2013), Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement. Arthritis Rheum, 65(5):1347-56.
PMID: 23335253
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yanaba K et al. (2013), Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. J Leukoc Biol, 94(4):563-73.
PMID: 23630391
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mae et al. (2013), Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun, 4(0):1367.
PMID: 23340407
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Hojo et al. (2013), Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium. J Biol Chem, 288(14):9924-32.
PMID: 23423383
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nasarre P et al. (2013), Neuropilin-2 Is upregulated in lung cancer cells during TGF-beta1-induced epithelial-mesenchymal transition. Cancer Res, 73(23):7111-21.
PMID: 24121493
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xu Z et al. (2013), Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-beta1 and platelet-derived growth factor BB. Mol Med Rep, 8(6):1715-21.
PMID: 24084832
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Hung C et al. (2013), Role of IGF-1 pathway in lung fibroblast activation. Respir Res, 14(0):102.
PMID: 24103846
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ammann J et al. (2013), Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J Immunol, 190(10):5030-6.
PMID: 23589618
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

O'Connor J et al. (2013), Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling. PLoS ONE, 8(12):e83188.
PMID: 24340092
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zhou Q et al. (2013), In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo. Cytokine, 65(1):56-64.
PMID: 24080164
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tannetta D et al. (2013), Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin. PLoS ONE, 8(2):e56754.
PMID: 23437230
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Keune W et al. (2013), Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression. Cancer Res, 73(23):6913-25.
PMID: 24127122
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2013), Transforming growth factor ÃŽÂ²-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis. Am J Pathol, 182(1):118-31.
PMID: 23142380
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Gu L et al. (2013), Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential. Lab Invest, 93(4):450-61.
PMID: 23439432
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Shinojima N et al. (2013), TGF-beta mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells. Cancer Res, 73(7):2333-44.
PMID: 23365134
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Bioassay

Gotz A et al. (2013), Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70. PLoS ONE, 8(3):e60642.
PMID: 23544157
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Stephens G et al. (2013), Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands. Eur J Immunol, 43(7):1727-34.
PMID: 23568529
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oliveira W et al. (2013), The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of human tegumentary leishmaniasis. Cytokine, 66(2):127-32.
PMID: 24485388
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Masani et al. (2013), Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination. Mol Cell Biol, 33(7):1468-73.
PMID: 23382073
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Serrano et al. (2013), Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun, 4(0):2976.
PMID: 24356468
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wang C et al. (2013), Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells. J Clin Invest, 123(4):1677-93.
PMID: 23478407
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sun H et al. (2013), Expression regulation of co-inhibitory molecules on human natural killer cells in response to cytokine stimulations. Cytokine, 65(1):33-41.
PMID: 24139237
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Long et al. (2013), MicroRNA-22 is a master regulator of bone morphogenetic protein-7/6 homeostasis in the kidney. J Biol Chem, 288(51):36202-14.
PMID: 24163368
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Ramdas V et al. (2013), Canonical transforming growth factor-beta signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29. Am J Pathol, 183(6):1885-96.
PMID: 24103556
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Liu Y et al. (2013), MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms. Oncogene, 32(3):296-306.
PMID: 22370643
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kinashi H et al. (2013), TGF-beta1 promotes lymphangiogenesis during peritoneal fibrosis. J Am Soc Nephrol, 24(10):1627-42.
PMID: 23990681
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Park J et al. (2013), FOG2 protein down-regulation by transforming growth factor-beta1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy. J Biol Chem, 288(31):22469-80.
PMID: 23788640
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Leung L et al. (2013), Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis. PLoS ONE, 8(12):e84366.
PMID: 24386371
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chen et al. (2013), H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 45(1):34-42.
PMID: 23202127
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Liu M et al. (2013), TGF-beta1 regulation of estrogen production in mature rat Leydig cells. PLoS ONE, 8(3):e60197.
PMID: 23555924
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lin Y et al. (2013), JNK inhibitor SP600125 enhances TGF-beta-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner. Mol Med Rep, 8(6):1623-9.
PMID: 24100678
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Geng L et al. (2013), TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis. PLoS ONE, 8(3):e59918.
PMID: 23536895
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Balli D et al. (2013), Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. EMBO J, 32(2):231-44.
PMID: 23288041
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nguyen H et al. (2013), Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture. Cancer Cell Int, 13(1):16.
PMID: 23409704
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tammaro A et al. (2013), Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy. PLoS ONE, 8(12):e82498.
PMID: 24358193
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Romero D et al. (2013), Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-beta/Smad signalling. J Cell Sci, 126(0):1858-67.
PMID: 23444370
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Scherz-Shouval R et al. (2013), The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell, 158(3):564-78.
PMID: 25083868
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hanieh H et al. (2013), MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration. Eur J Immunol, 43(10):2771-82.
PMID: 23780851
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Li J et al. (2012), Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients. J Biol Chem, 287(42):35484-95.
PMID: 22893706
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Radulovic K et al. (2012), CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential. J. Immunol., 188(4):2001-13.
PMID: 22250092
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Flanagan K et al. (2012), Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS. PLoS ONE, 7(7):e40443.
PMID: 22792325
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2012), Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis. J. Exp. Med., 209(11):2033-47.
PMID: 23071254
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Nakasone Y et al. (2012), Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma. Am. J. Pathol., 180(1):365-74.
PMID: 22037251
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2012), Progenitor-like traits contribute to patient survival and prognosis in oligodendroglial tumors. Clin. Cancer Res., 18(15):4122-35.
PMID: 22675171
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Casey KA et al. (2012), Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J. Immunol., 188(10):4866-75.
PMID: 22504644
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dupuy S et al. (2012), Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog., 8(1):e1002486.
PMID: 22253598
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cerchia et al. (2012), Targeting Axl with an high-affinity inhibitory aptamer. Mol Ther, 20(12):2291-303.
PMID: 22910292
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wilson TR et al. (2012), Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 487(7408):505-9.
PMID: 22763448
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Huse K et al. (2012), Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma. PLoS ONE, 7(10):e46117.
PMID: 23049692
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Abushahba W et al. (2012), Non-Canonical Smads Phosphorylation Induced by the Glutamate Release Inhibitor, Riluzole, through GSK3 Activation in Melanoma. PLoS ONE, 7(10):e47312.
PMID: 23077590
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Sohni A et al. (2012), TGF beta1-Induced Baf60c Regulates both Smooth Muscle Cell Commitment and Quiescence. PLoS ONE, 7(10):e47629.
PMID: 23110084
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Corvaisier M et al. (2012), IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation. PLoS Biol, 10(9):e1001395.
PMID: 23055831
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kudo et al. (2012), Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis. J Biol Chem, 287(46):38716-28.
PMID: 22992737
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bruce D et al. (2012), Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway. Cell Signal, 24(11):1999-2006.
PMID: 22781750
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

(2012), Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat. Med., 1248(0):18.
PMID: 22772464
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nam D et al. (2012), T-Lymphocytes Enable Osteoblast Maturation via IL-17F during the Early Phase of Fracture Repair. PLoS ONE, 7(6):e40044.
PMID: 22768215
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Grubisha MJ et al. (2012), A Local Paracrine and Endocrine Network Involving TGF beta, Cox-2, ROS, and Estrogen Receptor beta Influences Reactive Stromal Cell Regulation of Prostate Cancer Cell Motility. Mol. Endocrinol., 26(6):940-54.
PMID: 22593181
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pignatelli J et al. (2012), Hic-5 promotes invadopodia formation and invasion during TGF-beta-induced epithelial-mesenchymal transition. J. Cell Biol., 197(3):421-37.
PMID: 22529104
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Krishnan A et al. (2012), Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis. Lab Invest, 92(12):1712-25.
PMID: 23007134
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mottershead D et al. (2012), Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15. Mol Hum Reprod, 18(3):121-8.
PMID: 21911477
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)

Liu F et al. (2011), C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes. Diabetologia, 54(10):2713-23.
PMID: 21744073
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Peressin M et al. (2011), HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies. J. Virol., 85(2):1077-85.
PMID: 21084491
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gibbings S et al. (2011), Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha. J. Biol. Chem., 286(2):961-75.
PMID: 21059659
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yilmaz M et al. (2011), Transcription factor Dlx2 protects from TGFbeta-induced cell-cycle arrest and apoptosis. EMBO J., 30(21):4489-99.
PMID: 21897365
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

El-Behi M et al. (2011), The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol., 12(6):568-75.
PMID: 21516111
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bourne GL et al. (2011), Development and characterisation of an assay for furin activity. J. Immunol. Methods, 364(1):101-8.
PMID: 21112328
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Eisenwort G et al. (2011), Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-beta1-dependent human epidermal Langerhans cells. J. Invest. Dermatol., 131(10):2049-57.
PMID: 21677668
Species: Equine
Sample Types: Whole Cells
Applications: Bioassay

Ley C et al. (2011), Effects of high mobility group box protein-1, interleukin-1beta, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures. Connect. Tissue Res., 52(4):290-300.
PMID: 21117899
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ma Y et al. (2011), Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J. Exp. Med., 208(3):491-503.
PMID: 21383056
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Henriksson ML et al. (2011), Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion. Am. J. Pathol., 178(3):1387-94.
PMID: 21356388
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kashiwada M et al. (2011), NFIL3/E4BP4 controls type 2 T helper cell cytokine expression. EMBO J., 30(10):2071-82.
PMID: 21499227
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Jones GW et al. (2011), Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J., 25(1):409-19.
PMID: 20826539
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nakahama T et al. (2011), Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis. Proc. Natl. Acad. Sci. U.S.A., 108(34):14222-7.
PMID: 21825138
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Yamazaki S et al. (2011), Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell, 147(5):1146-58.
PMID: 22118468
Sierra-Filardi E et al. (2011), Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood, 117(19):5092-101.
PMID: 21389328
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Duchez S et al. (2011), Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation. Eur. J. Immunol., 41(12):3632-44.
PMID: 22076801
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Davis-Dusenbery BN et al. (2011), Down-regulation of Kruppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-{beta} and Bone Morphogenetic Protein 4. J. Biol. Chem., 286(32):28097-110.
PMID: 21673106
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay

Gregory PA et al. (2011), An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol. Biol. Cell, 22(10):1686-98.
PMID: 21411626
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Jin W et al. (2011), The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol., 12(0):68.
PMID: 22182253
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Kato N et al. (2011), Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. Am. J. Pathol., 178(2):572-9.
PMID: 21281789
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hoffman AM et al. (2011), Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung. Stem Cells Dev., 20(10):1779-92.
PMID: 21585237
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

DePaolo RW et al. (2011), Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature, 471(7337):220-4.
PMID: 21307853
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Zheng L et al. (2011), Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS ONE, 6(4):e19390.
PMID: 21572519
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Boswell S et al. (2011), Induction of latency-associated peptide (transforming growth factor-beta(1)) expression on CD4+ T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-alpha production in a transforming growth factor-beta-dependent manner. Immunology, 133(3):278-87.
PMID: 21426338
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Elkabets M et al. (2011), Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J. Clin. Invest., 121(2):784-99.
PMID: 21266779
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tan C et al. (2010), Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J. Immunol., 185(11):6795-801.
PMID: 20971929
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rai D et al. (2010), Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Proc. Natl. Acad. Sci. U.S.A., 107(7):3111-6.
PMID: 20133617
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chang HC et al. (2010), The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol., 11(6):527-34.
PMID: 20431622
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Moransard M et al. (2010), Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia, 58(5):559-71.
PMID: 19941340
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bohr W et al. (2010), Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein. PLoS ONE, 5(12):e16000.
PMID: 21209863
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Krueger C et al. (2010), Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. PLoS ONE, 5(11):e15511.
PMID: 21152098
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chen G et al. (2010), Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel. J. Immunol., 185(4):2350-9.
PMID: 20639489
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Maupin KA et al. (2010), Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems. PLoS ONE, 5(9):e13002.
PMID: 20885998
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jindra C (2010), Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. Eur J Immunol, 40(2):321-9.
PMID: 19950173
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lee WW et al. (2010), Regulating human Th17 cells via differential expression of IL-1 receptor. Blood, 115(3):530-40.
PMID: 19965648
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Yoshizaki A et al. (2010), Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J. Immunol., 185(4):2502-15.
PMID: 20624949
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Jones GW et al. (2010), Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J. Immunol., 184(4):2130-9.
PMID: 20083667
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Liu X et al. (2010), Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease. Nat. Med., 16(2):191-7.
PMID: 20062065
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Morizane S et al. (2010), Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J. Invest. Dermatol., 130(5):1297-306.
PMID: 20090765
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suzuki K et al. (2010), The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity, 33(1):71-83.
PMID: 20643338
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Roux J et al. (2010), Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. J. Biol. Chem., 285(7):4278-90.
PMID: 19996317
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Miyake T et al. (2010), Nuclear function of Smad7 promotes myogenesis. Mol. Cell. Biol., 30(3):722-35.
PMID: 19995910
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Boenisch O et al. (2010), TIM-3: a novel regulatory molecule of alloimmune activation. J. Immunol., 185(10):5806-19.
PMID: 20956339
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stockis J et al. (2009), Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg. Eur. J. Immunol., 39(12):3315-22.
PMID: 19750484
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pedroja BS et al. (2009), Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling. J. Biol. Chem., 284(0):20708.
PMID: 19487690
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Han Y et al. (2009), CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J. Immunol., 182(1):111-20.
PMID: 19109141
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sehrawat S et al. (2009), Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators. J. Immunol., 182(5):3191-201.
PMID: 19234217
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Duhen T et al. (2009), Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol., 10(8):857-63.
PMID: 19578369
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Duluc D et al. (2009), Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int. J. Cancer, 125(2):367-73.
PMID: 19378341
Species: N/A
Sample Types: N/A
Applications: Western Blot

Vitsky A et al. (2009), Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues. Am. J. Pathol., 174(6):2137-49.
PMID: 19406991
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Shi S et al. (2009), Growth factor regulation of growth factors in articular chondrocytes. J. Biol. Chem., 284(11):6697-704.
PMID: 19136669
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shafer SL et al. (2009), Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol., 46(5):621-35.
PMID: 19344627
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kinoshita H et al. (2009), Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol., 123(1):179-86.
PMID: 19056108
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sugiura H et al. (2009), Activation of Toll-like receptor 3 augments myofibroblast differentiation. Am. J. Respir. Cell Mol. Biol., 40(6):654-62.
PMID: 18988918
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Albanesi C et al. (2009), Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med., 206(1):249-58.
PMID: 19114666
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Boniface K et al. (2009), Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med., 206(3):535-48.
PMID: 19273625
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Margulis A et al. (2009), Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J. Immunol., 183(3):1739-50.
PMID: 19592653
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nolan-Stevaux O et al. (2009), GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev., 23(1):24-36.
PMID: 19136624
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

van Steensel L et al. (2009), Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy. Invest. Ophthalmol. Vis. Sci., 50(7):3091-8.
PMID: 19234339
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Amiable N et al. (2009), Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone, 44(6):1143-50.
PMID: 19264156
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Bhowmick S et al. (2009), Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection. Infect. Immun., 77(4):1514-23.
PMID: 19168736
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Duraisingham SS et al. (2009), TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses. J. Immunol., 183(4):2242-51.
PMID: 19625644
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Veraldi KL et al. (2009), Role of insulin-like growth factor binding protein-3 in allergic airway remodeling. Am. J. Respir. Crit. Care Med., 180(7):611-7.
PMID: 19608721
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aliahmadi E et al. (2009), TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur. J. Immunol., 39(5):1221-30.
PMID: 19350551
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dai Z et al. (2009), Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J. Exp. Med., 206(4):793-805.
PMID: 19289577
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Eid RE et al. (2009), Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 119(10):1424-32.
PMID: 19255340
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lamba S et al. (2009), Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism. Glia, 57(9):971-7.
PMID: 19062179
Species: Equine
Sample Types: Whole Cells
Applications: Bioassay

Reed SA et al. (2008), Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types. J. Cell. Physiol., 215(2):329-36.
PMID: 17929245
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ohba T et al. (2008), A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs. Arthritis Rheum., 58(11):3510-9.
PMID: 18975342
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kuchtey J et al. (2008), Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor. Invest. Ophthalmol. Vis. Sci., 49(8):3438-48.
PMID: 18421092
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Sheng MH et al. (2008), Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity. FEBS Lett., 582(10):1451-8.
PMID: 18381073
Species: Rabbit
Sample Types: In Vivo
Applications: In Vivo

Anderson BC et al. (2008), Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest. Ophthalmol. Vis. Sci., 49(1):221-9.
PMID: 18172096
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cox CA et al. (2008), Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. J. Immunol., 180(11):7414-22.
PMID: 18490741
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shinohara ML et al. (2008), Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity, 29(1):68-78.
PMID: 18619869
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Haydont V et al. (2008), Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-beta1. Am. J. Physiol., Cell Physiol., 294(6):C1332-41.
PMID: 18400984
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Marsh D et al. (2008), alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. Cancer Res., 68(9):3295-303.
PMID: 18451156
Species: Rat
Sample Types: Aqueous Humor
Applications: Bioassay

Ke Y et al. (2008), Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis. Invest. Ophthalmol. Vis. Sci., 49(9):3999-4007.
PMID: 18487362
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Pittet P et al. (2008), Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds. J. Cell. Sci., 121(0):877-86.
PMID: 18303045
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Walsh MF et al. (2008), Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via smad- and p38-dependent mechanisms. Am. J. Pathol., 173(2):385-99.
PMID: 18583311
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Tsoporis JN et al. (2008), Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha. J. Biol. Chem., 283(44):30174-83.
PMID: 18753141
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Guo B et al. (2008), The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest., 118(5):1680-90.
PMID: 18382764
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pen A et al. (2008), Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling. Oncogene, 27(54):6834-44.
PMID: 18711401
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Herman S et al. (2008), Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis. Arthritis Rheum., 58(10):3041-50.
PMID: 18821671
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Muranski P et al. (2008), Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood, 112(2):362-73.
PMID: 18354038
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aoudjehane L et al. (2008), Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway. Lab. Invest., 88(9):973-85.
PMID: 18626468
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Van Aarsen LA et al. (2008),