Recombinant Human TGF-beta 1 Protein
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Key Product Details
Source: | CHO |
Accession #: | P01137 |
Structure / Form: | Disulfide-linked homodimer |
Applications: | Bioactivity |
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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human TGF-beta 1 Protein include:
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Species: Human
Sample Types: Whole Cells
Applications: BioassayG Du et al. (2020), Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo Cell Death Dis, 11(2):118.
PMID: 32051399 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureK Watanabe et al. (2020), Group V secreted phospholipase A2 plays a protective role against aortic dissection J. Biol. Chem., 295(30):10092-10111.
PMID: 32482892 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLK Senavirath et al. (2020), Hypoxia and transforming growth factor &beta1 regulation of long non-coding RNA transcriptomes in human pulmonary fibroblasts Physiol Rep, 8(1):e14343.
PMID: 31925944 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureQM Nhu et al. (2020), Antifibrotic Effects of the Thiazolidinediones in Eosinophilic Esophagitis Pathologic Remodeling: A Preclinical Evaluation Clin Transl Gastroenterol, 11(4):e00164.
PMID: 32352681 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayÁ Torres et al. (2020), Intraglomerular Monocyte/Macrophage Infiltration and Macrophage-Myofibroblast Transition during Diabetic Nephropathy Is Regulated by the A2B Adenosine Receptor Cells, 9(4):.
PMID: 32340145 -
DP Cook et al. (2020), Context specificity of the EMT transcriptional response Nat Commun, 11(1):2142.
PMID: 32358524 -
Species: Human
Sample Types: Whole Cells
Applications: DifferentiationSS Beauford et al. (2020), Ionizing radiation modulates the phenotype and function of human CD4+ induced regulatory T cells BMC Immunol., 21(1):18.
PMID: 32299365 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureYH Wang et al. (2020), Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-&kappaB Signaling Pathway in Hepatic Stellate Cells Front Pharmacol, 11(0):388.
PMID: 32296336 -
Species: Human
Sample Types: Whole Cells
M Liu et al. (2020), HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma Cancer Med, 0(0):.
PMID: 32281284 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIS Kang et al. (2020), Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation Sci Rep, 10(1):7024.
PMID: 32341385 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Hurrell et al. (2020), Human Liver Spheroids as a Model to Study Aetiology and Treatment of Hepatic Fibrosis Cells, 9(4):.
PMID: 32295224 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureR Xu et al. (2020), IL-35 is critical in suppressing superantigenic Staphylococcus aureus-driven inflammatory Th17 responses in human nasopharynx-associated lymphoid tissue Mucosal Immunol, 13(3):460-470.
PMID: 31896761 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAM Steitz et al. (2020), Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C Cell Death Dis, 11(4):249.
PMID: 32312959 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureN Ogasawara et al. (2020), Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps Mucosal Immunol, 13(1):86-95.
PMID: 31641233 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayW Lei et al. (2020), The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice Sci Rep, 10(1):7004.
PMID: 32332865 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMND Svensson et al. (2020), Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal Sci Adv, 6(26):eaba4353.
PMID: 32637608 -
Species: Rat
Sample Types: Whole Cell
Applications: BioassayC Zogbi et al. (2020), Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells Sci Rep, 10(1):12350.
PMID: 32704142 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureA Fujiwara et al. (2020), Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer Sci Rep, 10(1):10900.
PMID: 32616870 -
Species: Human
Sample Types: Cells
Applications: Cell CultureR Fonseca et al. (2020), Developmental plasticity allows outside-in immune responses by resident memory T cells Nat. Immunol., 0(0):.
PMID: 32066954 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Ma et al. (2020), Melatonin ameliorates necrotizing enterocolitis by preventing Th17/Treg imbalance through activation of the AMPK/SIRT1 pathway Theranostics, 10(17):7730-7746.
PMID: 32685016 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHY Seo et al. (2020), Src Inhibition Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation and Decreasing Connetive Tissue Growth Factor Cells, 9(3):.
PMID: 32120837 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Fan et al. (2020), Targeting the Notch and TGF-&beta signaling pathways to prevent retinal fibrosis in vitro and in vivo Theranostics, 10(18):7956-7973.
PMID: 32724452 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Krüger et al. (2019), Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair Int J Mol Sci, 20(17):.
PMID: 31480518 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Argemi et al. (2019), Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis Nat Commun, 10(1):3126.
PMID: 31311938 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureS Saraswati et al. (2019), Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing Nat Commun, 10(1):3027.
PMID: 31289275 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Sreekumar et al. (2019), Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC Cell Death Dis, 10(10):703.
PMID: 31543517 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Aoki et al. (2019), Sphingosine-1-Phosphate Facilitates Skin Wound Healing by Increasing Angiogenesis and Inflammatory Cell Recruitment with Less Scar Formation Int J Mol Sci, 20(14):.
PMID: 31295813 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Messerschm et al. (2019), Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation Mol. Vis., 25(0):329-344.
PMID: 31341381 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Pedroza et al. (2019), Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride PLoS ONE, 14(7):e0218971.
PMID: 31269038 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDR Myers et al. (2019), Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells Cell Rep, 27(6):1858-1874.e6.
PMID: 31067469 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR van Dalen et al. (2019), Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses MBio, 10(3):.
PMID: 31088921 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Sakata et al. (2019), HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma Int J Mol Sci, 20(10):.
PMID: 31109142 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCJW Stock et al. (2019), Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation Biomed Res Int, 2019(0):1484736.
PMID: 31119153 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYH Lee et al. (2019), Effect of exposure to Asian sand dust-Particulate matter on liver Tenascin-C expression in human cancer cell and mouse hepatic tissue J Toxicol Sci, 44(9):633-641.
PMID: 31474744 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Du et al. (2019), Aurora A selective inhibitor LY3295668 leads to dominant mitotic arrest, apoptosis in cancer cells and shows potent preclinical antitumor efficacy Mol. Cancer Ther., 0(0):.
PMID: 31530649 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCL Hammond et al. (2019), Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor PLoS ONE, 14(9):e0222779.
PMID: 31536596 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureLP Garo et al. (2019), Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity Cell Rep, 28(13):3353-3366.e5.
PMID: 31553906 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDM Habiel et al. (2019), DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis BMC Pulm Med, 19(1):165.
PMID: 31464599 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Kamitani et al. (2019), Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease J. Dermatol. Sci., 0(0):.
PMID: 31570272 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Duan et al. (2019), Rational Reprogramming of Cellular States by Combinatorial Perturbation Cell Rep, 27(12):3486-3499.e6.
PMID: 31216470 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Berning et al. (2019), In vitro selective cytotoxicity of the dietary chalcone cardamonin (CD) on melanoma compared to healthy cells is mediated by apoptosis PLoS ONE, 14(9):e0222267.
PMID: 31553748 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA StandardN Kaushansky et al. (2019), Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms J. Immunol., 0(0):.
PMID: 31484731 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayS Granados-A et al. (2019), SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles Sci Rep, 9(1):6513.
PMID: 31015579 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYJ Choi et al. (2019), Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A Stem Cell Res Ther, 10(1):291.
PMID: 31547873 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Lv et al. (2019), MicroRNA?155 inhibits the proliferation of CD8+ T�cells via upregulating regulatory T cells in vitiligo Mol Med Rep, 20(4):3617-3624.
PMID: 31485649 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTTD Luong et al. (2019), Inhibition of vascular smooth muscle cell calcification by vasorin through interference with TGF β1 signaling Cell. Signal., 0(0):109414.
PMID: 31505229 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureM Bogdanova et al. (2019), Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties Sci Rep, 9(1):12934.
PMID: 31506459 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Diao et al. (2019), Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma J. Cell. Mol. Med., 0(0):.
PMID: 30950191 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Wang et al. (2019), TGF-?1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM EBioMedicine, 0(0):.
PMID: 30926424 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Peng et al. (2019), Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway Lab. Invest., 0(0):.
PMID: 30976056 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Derada Tro et al. (2019), Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology Cell Death Dis, 10(2):45.
PMID: 30718504 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Zheng et al. (2019), Integrated analysis of long non-coding RNAs and mRNAs associated with peritendinous fibrosis J Adv Res, 15(0):49-58.
PMID: 30581612 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Martin-Mat et al. (2019), Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-? Dependent Hepatic Stellate Cell Activation and Liver Fibrosis Cell Mol Gastroenterol Hepatol, 7(1):197-209.
PMID: 30539787 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Kijewska et al. (2019), Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain Breast Cancer Res., 21(1):4.
PMID: 30642388 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAG Kunihiro et al. (2019), Curcumin, but not curcumin-glucuronide, inhibits Smad signaling in TGF?-dependent bone metastatic breast cancer cells and is enriched in bone compared to other tissues J. Nutr. Biochem., 63(0):150-156.
PMID: 30393127 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayB Wang et al. (2019), POH1 contributes to hyperactivation of TGF-? signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-? receptors and caveolin-1 EBioMedicine, 0(0):.
PMID: 30745168 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Zhang et al. (2019), TGFb1 suppresses the activation of distinct dNK subpopulations in preeclampsia EBioMedicine, 39(0):531-539.
PMID: 30579870 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBW Liu et al. (2019), Estrogen receptor-?-miR-1271-SNAI2 feedback loop regulates transforming growth factor-?-induced breast cancer progression J. Exp. Clin. Cancer Res., 38(1):109.
PMID: 30823890 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Gao et al. (2019), Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-?1 in bladder cancer cells J. Exp. Clin. Cancer Res., 38(1):111.
PMID: 30823924 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Yamashita et al. (2019), Increased expression of aquaporin-1 in dermal fibroblasts and dermal microvascular endothelial cells possibly contributes to skin fibrosis and edema in patients with systemic sclerosis J. Dermatol. Sci., 93(1):24-32.
PMID: 30270117 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySS Kim et al. (2019), Fibronectin synthesis, but not ?-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling Sci Rep, 9(1):2708.
PMID: 30804350 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJN Pucella et al. (2019), The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses J. Immunol., 0(0):.
PMID: 30683701 -
Species: Mouse
Sample Types: Spheroids
Applications: BioassayI Mannaerts et al. (2019), Unfolded protein response is an early, non-critical event during hepatic stellate cell activation Cell Death Dis, 10(2):98.
PMID: 30718473 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Higuchi et al. (2019), Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment Arthritis Res. Ther., 21(1):103.
PMID: 30999934 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRK Dutta et al. (2019), A Neutralizing Aptamer to TGFBR2 and miR-145 Antagonism Rescue Cigarette Smoke- and TGF-?-Mediated CFTR Expression Mol. Ther., 27(2):442-455.
PMID: 30595527 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Luo et al. (2019), Negligible Effect of Sodium Chloride on the Development and Function of TGF-?-Induced CD4+ Foxp3+ Regulatory T Cells Cell Rep, 26(7):1869-1879.e3.
PMID: 30759396 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Yasuda et al. (2019), Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation Nat Commun, 10(1):549.
PMID: 30710091 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureF Yao et al. (2019), ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription Lab. Invest., 0(0):.
PMID: 31641227 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Gramlich et al. (2019), In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists Int J Mol Sci, 20(6):.
PMID: 30893757 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Hochdörfer et al. (2019), Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells Eur. J. Immunol., 0(0):.
PMID: 30892687 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYB Kim et al. (2019), Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis Cell. Mol. Immunol., 0(0):.
PMID: 30842627 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJS Park et al. (2019), Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma Nat Commun, 10(1):1128.
PMID: 30850660 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDQ Chen et al. (2019), Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan Nat Commun, 10(1):1476.
PMID: 30931940 -
Species: Human
Sample Types: Whole Cells
V Fleskens et al. (2019), Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells Cell Rep, 26(13):3600-3612.e6.
PMID: 30917315 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMR Hadjichara et al. (2019), Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis Sci Rep, 9(1):6020.
PMID: 30988425 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Zhou et al. (2019), Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC) EBioMedicine, 0(0):.
PMID: 31522982 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHC Lien et al. (2019), Fibrillin-1, a novel TGF-beta-induced factor, is preferentially expressed in metaplastic carcinoma with spindle sarcomatous metaplasia Pathology, 0(0):.
PMID: 31010590 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayJH Choi et al. (2019), Platyconic Acid A, Platycodi Radix-Derived Saponin, Suppresses TGF-1-induced Activation of Hepatic Stellate Cells via Blocking SMAD and Activating the PPAR Signaling Pathway Cells, 8(12):.
PMID: 31795488 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Li et al. (2019), Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells Redox Biol, 28(0):101373.
PMID: 31731100 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Bhatia et al. (2019), Mitophagy dependent macrophage reprogramming protects against kidney fibrosis JCI Insight, 0(0):.
PMID: 31639106 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Acheva et al. (2019), Presence of Stromal Cells Enhances Epithelial-to-Mesenchymal Transition (EMT) Induction in Lung Bronchial Epithelium after Protracted Exposure to Oxidative Stress of Gamma Radiation Oxid Med Cell Longev, 2019(0):4120379.
PMID: 31583039 -
Species: Human
Sample Types: Whole Cells
Applications: Tissue CultureR Sachdeva et al. (2019), BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma Sci Rep, 9(1):14569.
PMID: 31602000 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayD Pham et al. (2019), Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf Cell Rep, 29(5):1203-1220.e7.
PMID: 31665634 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayB Li et al. (2019), Clonorchis sinensis ESPs enhance the activation of hepatic stellate cells by a cross-talk of TLR4 and TGF-beta/Smads Signaling pathway Acta Trop., 0(0):105307.
PMID: 31862462 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYZ Huang et al. (2019), Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner Stem Cells Int, 2019(0):4242178.
PMID: 31885606 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Tochimoto et al. (2019), S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma Lab. Invest., 0(0):.
PMID: 31857700 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Huang et al. (2019), Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells Cancer Cell Int., 19(0):306.
PMID: 31832019 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Li et al. (2019), TGFbeta induces stemness through non-canonical AKT-FOXO3a axis in oral squamous cell carcinoma EBioMedicine, 0(0):.
PMID: 31629677 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PN Uyama et al. (2019), Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation Sci Rep, 9(1):17558.
PMID: 31772282 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureM Krämer et al. (2019), Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system Cell. Signal., 65(0):109432.
PMID: 31693876 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureAW Horne et al. (2019), Repurposing dichloroacetate for the treatment of women with endometriosis Proc. Natl. Acad. Sci. U.S.A., 116(51):25389-25391.
PMID: 31792175 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureRW Scott et al. (2019), Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration Cell Stem Cell, 25(6):797-813.e9.
PMID: 31809738 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureL Andersen et al. (2019), The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells Cell Rep, 29(13):4447-4459.e6.
PMID: 31875552 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureE Foxall et al. (2019), PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells Cell Rep, 29(11):3385-3393.e6.
PMID: 31825823 -
Species: Human
Sample Types: Whole Cells
Applications: StimulationP Stylianou et al. (2019), Tensin1 expression and function in chronic obstructive pulmonary disease Sci Rep, 9(1):18942.
PMID: 31831813 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBS Ni et al. (2019), Plug-and-Play In Vitro Metastasis System toward Recapitulating the Metastatic Cascade Sci Rep, 9(1):18110.
PMID: 31792319 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYC Kim et al. (2019), ST2 blockade mitigates peritoneal fibrosis induced by TGF-beta and high glucose J. Cell. Mol. Med., 23(10):6872-6884.
PMID: 31397957 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureH Basma et al. (2019), TGF-beta induces a heart failure phenotype via fibroblasts exosome signaling Heliyon, 5(10):e02633.
PMID: 31687497 -
Species: Mink
Sample Types: Whole Cells
Applications: BioassayS Holvoet et al. (2019), Oral Tolerance Induction to Newly Introduced Allergen is Favored by a Transforming Growth Factor-beta-Enriched Formula Nutrients, 11(9):.
PMID: 31540231 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayW Yoo et al. (2019), Progranulin attenuates liver fibrosis by downregulating the inflammatory response Cell Death Dis, 10(10):758.
PMID: 31591383 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureV Welk et al. (2019), Proteasome activator PA200 regulates myofibroblast differentiation Sci Rep, 9(1):15224.
PMID: 31645612 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayW Chen et al. (2018), ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells Sci Rep, 8(1):16636.
PMID: 30413785 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Inoue et al. (2018), Arginine methylation controls the strength of ?c-family cytokine signaling in T cell maintenance Nat. Immunol., 19(11):1265-1276.
PMID: 30323341 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJT Chen et al. (2018), Curcumin inhibits TGF-?1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts J. Formos. Med. Assoc., 0(0):.
PMID: 29339038 -
Species: Fish
Sample Types: In Vivo
Applications: In VivoMR Conith et al. (2018), Genetic and developmental origins of a unique foraging adaptation in a Lake Malawi cichlid genus Proc. Natl. Acad. Sci. U.S.A., 0(0):.
PMID: 29915062 -
Species: Equine
Sample Types: Whole Cells
Applications: BioassayM Desancé et al. (2018), Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy Int J Mol Sci, 19(2):.
PMID: 29439436 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCB Cummins et al. (2018), Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway Int J Mol Sci, 19(6):.
PMID: 29795016 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Hu et al. (2018), Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells Oncol Lett, 15(4):4867-4872.
PMID: 29552126 -
Applications: ELISA (Standard)CC Tsai et al. (2018), Essential role of connective tissue growth factor (CTGF) in transforming growth factor-?1 (TGF-?1)-induced myofibroblast transdifferentiation from Graves' orbital fibroblasts Sci Rep, 8(1):7276.
PMID: 29739987 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Jiang et al. (2018), Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28 Nat Commun, 9(1):1424.
PMID: 29651155 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Liu et al. (2018), Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus JCI Insight, 3(23):.
PMID: 30518690 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBS Nepon-Sixt et al. (2018), TGF�1 Cell Cycle Arrest Is Mediated by Inhibition of MCM Assembly in Rb-deficient Conditions Mol. Cancer Res., 0(0):.
PMID: 30257992 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKB Kaylan et al. (2018), Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling Elife, 7(0):.
PMID: 30589410 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Mallikarju et al. (2018), VHL status regulates transforming growth factor-? signaling pathways in renal cell carcinoma Oncotarget, 9(23):16297-16310.
PMID: 29662646 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Fang et al. (2018), A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells Nat Commun, 9(1):4384.
PMID: 30349051 -
Species: Porcine
Sample Types: Plasma
Applications: BioassayT Huang et al. (2018), Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs Vet. Res., 49(1):121.
PMID: 30541630 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Beaulieu L et al. (2018), TGF-?1 promotes cell barrier function upon maturation of corneal endothelial cells Sci Rep, 8(1):4438.
PMID: 29535350 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPD Leiphrakpa et al. (2018), TGF? and IGF1R signaling activate protein kinase A through differential regulation of ezrin phosphorylation in colon cancer�cells J. Biol. Chem., 0(0):.
PMID: 29599290 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Jia et al. (2018), The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/?-Catenin pathway Onco Targets Ther, 11(0):313-321.
PMID: 29391808 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Thome et al. (2018), Chloroquine-treated dendritic cells require STAT1 signaling for their tolerogenic activity Eur. J. Immunol., 0(0):.
PMID: 29572810 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayX Zhang et al. (2018), MicroRNA 483-3p targets Pard3 to potentiate TGF-?1-induced cell migration, invasion, and epithelial-mesenchymal transition in anaplastic thyroid cancer cells Oncogene, 0(0):.
PMID: 30171257 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Lin et al. (2018), FPPS mediates TGF-?1-induced non-small cell lung cancer cell invasion and the EMT process via the RhoA/Rock1 pathway Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29337059 -
Species: Canine
Sample Types: Whole Cells
Applications: BioassaySJ Han et al. (2018), Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29337054 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Guo et al. (2018), D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion Stem Cells Int, 2018(0):7168231.
PMID: 30271438 -
Species: Canine
Sample Types: Whole Cells
Applications: BioassayFC Bach et al. (2018), Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside Oncotarget, 9(41):26507-26526.
PMID: 29899873 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Amir et al. (2018), REV-ERB? Regulates TH17 Cell Development and Autoimmunity Cell Rep, 25(13):3733-3749.e8.
PMID: 30590045 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Wang et al. (2018), The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells Cell. Physiol. Biochem., 51(6):2547-2563.
PMID: 30562730 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Yang et al. (2018), Hydrogen sulfide promotes immunomodulation of gingiva-derived mesenchymal stem cells via the Fas/FasL coupling pathway Stem Cell Res Ther, 9(1):62.
PMID: 29523215 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Chen et al. (2018), Overexpression of LncRNA AC067945.2 Down-Regulates Collagen Expression in Skin Fibroblasts and Possibly Correlates with the VEGF and Wnt Signalling Pathways Cell. Physiol. Biochem., 45(2):761-771.
PMID: 29414824 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJS Park et al. (2018), A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells Stem Cells, 0(0):.
PMID: 30444564 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Nowsheen et al. (2018), L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage Nat. Cell Biol., 20(4):455-464.
PMID: 29581593 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCC Weng et al. (2018), Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis Oncogene, 0(0):.
PMID: 30467381 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Nishida et al. (2018), Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-?-dependent and -independent mechanisms Oncogene, 0(0):.
PMID: 29391598 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYT Tang et al. (2018), Alterations in exosomal miRNA profile upon epithelial-mesenchymal transition in human lung cancer cell lines BMC Genomics, 19(1):802.
PMID: 30400814 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLR Penke et al. (2018), FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis J. Clin. Invest., 0(0):.
PMID: 29733296 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Nakayama et al. (2018), TGF?1-induced Amelotin gene expression is downregulated by Bax expression in mouse gingival epithelial cells J Oral Sci, 0(0):.
PMID: 29657250 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Park et al. (2018), Additive effect of bFGF and selenium on expansion and paracrine action of human amniotic fluid-derived mesenchymal stem cells Stem Cell Res Ther, 9(1):293.
PMID: 30409167 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMM Pleumeeker et al. (2018), Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture PLoS ONE, 13(2):e0190744.
PMID: 29489829 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayN Zila et al. (2018), Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases Clin Proteomics, 15(0):13.
PMID: 29541007 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Saxena et al. (2018), PyMT-1099, a versatile murine cell model for EMT in breast cancer Sci Rep, 8(1):12123.
PMID: 30108334 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKH Kim et al. (2018), A standardized herbal extract PM014 ameliorates pulmonary fibrosis by suppressing the TGF-?1 pathway Sci Rep, 8(1):16860.
PMID: 30443024 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYW Liao et al. (2018), miR-200b ameliorates myofibroblast transdifferentiation in precancerous oral submucous fibrosis through targeting ZEB2 J. Cell. Mol. Med., 0(0):.
PMID: 29893466 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Schmidt et al. (2018), Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3 BMC Biol., 16(1):47.
PMID: 29730990 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Dvornikov et al. (2018), Expression ratio of the TGF?-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response Sci Rep, 8(1):9517.
PMID: 29934580 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Zhang et al. (2018), DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway J. Immunol., 0(0):.
PMID: 29378913 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayF Das et al. (2018), Akt2 causes TGF?-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression PLoS ONE, 13(11):e0207285.
PMID: 30444896 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Životi? et al. (2018), Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells PLoS ONE, 13(11):e0206786.
PMID: 30383875 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Tiwary et al. (2018), Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a Sci Rep, 8(1):8267.
PMID: 29844613 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Wang et al. (2018), Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype Int J Mol Sci, 19(2):.
PMID: 29419805 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Schlereth et al. (2018), The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium Elife, 7(0):.
PMID: 29749927 -
Species: Rabbit
Sample Types: Whole Cells
Applications: BioassayX Feng et al. (2018), Injectable cartilaginous template transformed BMSCs into vascularized bone Sci Rep, 8(1):8244.
PMID: 29844536 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayYH Chung et al. (2018), BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-?1 signaling Lab. Invest., 0(0):.
PMID: 29789683 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Zhu et al. (2018), MicroRNA-212 activates hepatic stellate cells and promotes liver fibrosis via targeting SMAD7 Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29307832 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Choi et al. (2018), P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells Immunology, 0(0):.
PMID: 29297928 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Patalano et al. (2018), CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation Sci Rep, 8(1):3499.
PMID: 29472636 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Deng et al. (2018), TNFRSF19 inhibits TGF? signaling through interaction with TGF? receptor type I to promote tumorigenesis Cancer Res., 0(0):.
PMID: 29735548 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayF Ghodrati et al. (2018), The prion protein is embedded in a molecular environment that modulates transforming growth factor ? and integrin signaling Sci Rep, 8(1):8654.
PMID: 29872131 -
Species: Human
Sample Types: Complex Sample Type
Applications: BioassayG Zhou et al. (2018), In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction EBioMedicine, 28(0):287-302.
PMID: 29396297 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Ottaviani et al. (2018), TGF-? induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression Nat Commun, 9(1):1845.
PMID: 29748571 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Deshpande et al. (2018), Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy Sci Rep, 8(1):6954.
PMID: 29725042 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayR Zhang et al. (2018), RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke Cell Death Differ., 0(0):.
PMID: 29396549 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZ Qin et al. (2018), Actin cytoskeleton assembly regulates collagen production via TGF-? type II receptor in human skin fibroblasts J. Cell. Mol. Med., 0(0):.
PMID: 29888864 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Wang et al. (2018), Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling J. Cell. Mol. Med., 0(0):.
PMID: 29516637 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZ Al Shareef et al. (2018), Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 Oncogene, 0(0):.
PMID: 29858602 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Sugiura et al. (2018), Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model PLoS ONE, 13(3):e0191706.
PMID: 29518087 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Knüppel et al. (2018), FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis Respir. Res., 19(1):67.
PMID: 29673351 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Geng et al. (2018), MicroRNA-663 induces immune dysregulation by inhibiting TGF-?1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus Cell. Mol. Immunol., 0(0):.
PMID: 29578533 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Huang et al. (2018), CD8+ T cells with high TGF??1 expression cause lymph node fibrosis following HIV infection Mol Med Rep, 0(0):.
PMID: 29749506 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Park et al. (2018), Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation J Cancer Prev, 23(1):1-9.
PMID: 29629343 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayB Zhang et al. (2018), Hypoxia induces endothelial?mesenchymal transition in pulmonary vascular remodeling Int. J. Mol. Med., 0(0):.
PMID: 29568878 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Liu et al. (2018), Metformin ameliorates TGF-β1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting β-catenin signaling Biochem. Biophys. Res. Commun., 0(0):.
PMID: 29679571 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Wu et al. (2018), Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis Mol. Hum. Reprod., 0(0):.
PMID: 29660008 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Murillo-Ga et al. (2018), Frizzled-8 integrates Wnt-11 and transforming growth factor-? signaling in prostate cancer Nat Commun, 9(1):1747.
PMID: 29717114 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureM Wang et al. (2018), Novel inhibitors of the cellular RAS components, Poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis Br. J. Pharmacol., 0(0):.
PMID: 29679507 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayS Lively et al. (2018), Comparing Effects of Transforming Growth Factor ?1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels Front Cell Neurosci, 12(0):115.
PMID: 29780305 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA StandardL Corsuto et al. (2018), Sulfation degree not origin of chondroitin sulfate derivatives modulates keratinocyte response Carbohydr Polym, 191(0):53-64.
PMID: 29661321 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Gupta et al. (2018), DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity Cell, 0(0):.
PMID: 29656893 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayE Groppa et al. (2018), EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF EMBO Rep., 0(0):.
PMID: 29643120 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Zaiatz-Bit et al. (2018), Canonical TGF-? Signaling Pathway Represses Human NK Cell Metabolism J. Immunol., 0(0):.
PMID: 29720425 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Imamura et al. (2018), RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase JCI Insight, 3(3):.
PMID: 29415885 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCF Hung et al. (2018), Role of integrin alpha8 in murine model of lung fibrosis PLoS ONE, 13(5):e0197937.
PMID: 29813125 -
Species: Human
Sample Types: Transfected Whole Cells
Applications: BioassayRJ Marsh et al. (2018), Artifact-free high-density localization microscopy analysis Nat. Methods, 0(0):.
PMID: 30061677 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJM Dave et al. (2018), Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain Dev. Cell, 0(0):.
PMID: 29456135 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayO Kodet et al. (2018), Microenvironment?driven resistance to B?Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts Int. J. Mol. Med., 0(0):.
PMID: 29393387 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Löfdahl et al. (2018), Effects of 5-HT2receptor antagonists on bronchoconstriction and pulmonary remodeling processes Am. J. Pathol., 0(0):.
PMID: 29454752 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Merdrignac et al. (2018), A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma Hepatol Commun, 2(3):254-269.
PMID: 29507901 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Tian et al. (2018), Endoglin interacts with VEGFR2 to promote angiogenesis FASEB J., 0(0):fj201700867RR.
PMID: 29401587 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureL Gagnon et al. (2018), A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84 Am. J. Pathol., 0(0):.
PMID: 29454750 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Rekik et al. (2018), Impaired TGF-? signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22 Cytokine, 108(0):182-189.
PMID: 29684755 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureK Kobayashi et al. (2018), Role of monocyte chemoattractant protein-1 in liver fibrosis with transient myeloproliferative disorder in down syndrome Hepatol Commun, 2(3):230-236.
PMID: 29507898 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Wang et al. (2018), Identification of a TGF-?-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells FASEB J., 0(0):fj201701199R.
PMID: 29465312 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Rosengren et al. (2018), TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms Cell. Mol. Life Sci., 0(0):.
PMID: 29396625 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Losa et al. (2018), Face morphogenesis is promoted by Pbx-dependent EMT via regulation ofduring frontonasal prominence fusion Development, 0(0):.
PMID: 29437830 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Bozatzi et al. (2018), PAWS1 controls Wnt signalling through association with casein kinase 1? EMBO Rep., 0(0):.
PMID: 29514862 -
Species: Canine
Sample Types: Whole Cells
Applications: BioassayS Liu et al. (2018), Ras enhances TGF-? signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1 Cell Commun. Signal, 16(1):10.
PMID: 29534718 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Fraser et al. (2018), A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials Mol Ther Methods Clin Dev, 8(0):198-209.
PMID: 29552576 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Kunita et al. (2018), MicroRNA-21 in cancer-associated fibroblasts supports�lung adenocarcinoma progression Sci Rep, 8(1):8838.
PMID: 29892003 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureT Yamakawa et al. (2018), Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease Blood, 0(0):.
PMID: 29363541 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPS Bellaye et al. (2018), Synergistic role of HSP90? and HSP90? to promote myofibroblast persistence in lung fibrosis Eur. Respir. J., 51(2):.
PMID: 29386344 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVNS Garikipati et al. (2018), Isolation and characterization of mesenchymal stem cells from human fetus heart PLoS ONE, 13(2):e0192244.
PMID: 29420637 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDJ Sharkey et al. (2018), Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells Biol. Reprod., 0(0):.
PMID: 29596569 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySD Hardy et al. (2017), Regulation of epithelial-mesenchymal transition and metastasis by TGF-?, P-bodies, and autophagy Oncotarget, 8(61):103302-103314.
PMID: 29262563 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Shin et al. (2017), V-set and Ig domain-containing 4 (VSIG4)-expressing hepatic F4/80+ cells regulate oral antigen-specific responses in mouse Eur. J. Immunol., 0(0):.
PMID: 29235119 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKA Whelan et al. (2017), Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance Oncogene, 0(0):.
PMID: 28414310 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJB Koo et al. (2017), Anti-fibrogenic effect of PPAR-? agonists in human intestinal myofibroblasts BMC Gastroenterol, 17(1):73.
PMID: 28592228 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Siddiqui et al. (2017), Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells J. Pathol, 0(0):.
PMID: 28337746 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Hanieh et al. (2017), Arid5a stabilizes OX40 mRNA in murine CD4+ T cells by recognizing a stem-loop structure in its 3'UTR Eur. J. Immunol., 0(0):.
PMID: 29244194 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Kamata et al. (2017), KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis Sci Rep, 7(1):4556.
PMID: 28676645 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Pan et al. (2017), Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis Scand. J. Immunol., 0(0):.
PMID: 28376277 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayN Salvarani et al. (2017), TGF-?1 (Transforming Growth Factor-?1) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity Circ Arrhythm Electrophysiol, 10(5):e004567.
PMID: 28500173 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Qi et al. (2017), Transforming growth factor-?1 signaling promotes epithelial-mesenchymal transition-like phenomena, cell motility, and cell invasion in synovial sarcoma cells PLoS ONE, 12(8):e0182680.
PMID: 28829837 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassaySZ Wu et al. (2017), Dual roles of parathyroid hormone-related protein in TGF-?1 signaling and fibronectin upregulation in mesangial cells Biosci. Rep., 0(0):.
PMID: 28954822 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Yu et al. (2017), Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2 Cell. Physiol. Biochem., 43(6):2242-2252.
PMID: 29073595 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayW Zhao et al. (2017), Cdk5 is required for the neuroprotective effect of transforming growth factor-?1 against cerebral ischemia-reperfusion Biochem. Biophys. Res. Commun, 0(0):.
PMID: 28254431 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Zhang (2017), Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/?-catenin signaling Biochem. Biophys. Res. Commun., 0(0):.
PMID: 28427938 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEM Reyes-Reye et al. (2017), LINE-1 couples EMT programming with acquisition of oncogenic phenotypes in human bronchial epithelial cells Oncotarget, 8(61):103828-103842.
PMID: 29262603 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJJ Kathiriya et al. (2017), Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis Cell Death Discov, 3(0):17010.
PMID: 28417017 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Iizuka et al. (2017), Hydrogen Peroxide Enhances TGF?-mediated Epithelial-to-Mesenchymal Transition in Human Mammary Epithelial MCF-10A Cells Anticancer Res, 37(3):987-995.
PMID: 28314256 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Saito et al. (2017), Tubastatin ameliorates pulmonary fibrosis by targeting the TGF?-PI3K-Akt pathway PLoS ONE, 12(10):e0186615.
PMID: 29045477 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYL Li et al. (2017), GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway Oncotarget, 8(1):1508-1528.
PMID: 27903972 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Dimitrova et al. (2017), TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition Biol. Direct, 12(1):8.
PMID: 28412966 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDW Hammers et al. (2017), Supraphysiological levels of GDF11 induce striated muscle atrophy EMBO Mol Med, 0(0):.
PMID: 28270449 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayT Ruetz et al. (2017), Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming Cell Stem Cell, 0(0):.
PMID: 29174331 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Zhou et al. (2017), Cytidine monophosphate kinase is inhibited by the TGF-? signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer Cell. Signal., 0(0):.
PMID: 28414100 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySK Sahu et al. (2017), FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development Nat Commun, 8(1):1523.
PMID: 29142217 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayC Caër et al. (2017), Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue Sci Rep, 7(1):3000.
PMID: 28592801 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Mondanelli et al. (2017), A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells Immunity, 46(2):233-244.
PMID: 28214225 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Desai et al. (2017), HR+HER2- breast cancers with growth factor receptor-mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells Tumour Biol, 39(3):1010428317695.
PMID: 28349782 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayY Tachida et al. (2017), Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells Biol Open, 6(3):370-380.
PMID: 28298363 -
Species: Chicken
Sample Types: Whole Cells
Applications: BioassayBA Boswell et al. (2017), Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract Mol. Biol. Cell, 0(0):.
PMID: 28209733 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEJ Kim et al. (2017), Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties Clin Orthop Surg, 9(2):239-248.
PMID: 28567229 -
S Lee et al. (2017), Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production Cell. Physiol. Biochem., 42(4):1684-1700.
PMID: 28743125 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJC Cheng et al. (2017), TGF-?1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation Cell. Signal., 43(0):55-61.
PMID: 29269046 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZM Zhao et al. (2017), Levistilide A inhibits angiogenesis in liver fibrosis via vascular endothelial growth factor signaling pathway Exp. Biol. Med. (Maywood), 242(9):974-985.
PMID: 28440736 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Hu et al. (2017), Armc5 deletion causes developmental defects and compromises T-cell immune responses Nat Commun, 8(0):13834.
PMID: 28169274 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTP Nguyen et al. (2017), TGF-? inhibits IL-7-induced proliferation in memory but not naive human CD4(+) T cells J. Leukoc. Biol., 0(0):.
PMID: 28588029 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Calvier et al. (2017), PPAR? Links BMP2 and TGF?1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism Cell Metab., 25(5):1118-1134.e7.
PMID: 28467929 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Pap et al. (2017), Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammation and Tissue Remodeling Kidney Blood Press. Res, 42(1):16-32.
PMID: 28253513 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Ghatak et al. (2017), TGF beta-1 induced CD44v6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis J. Biol. Chem., 0(0):.
PMID: 28389561 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayC Pagiatakis et al. (2017), TGF?-TAZ/SRF Signaling regulates vascular smooth muscle cell differentiation FEBS J, 0(0):.
PMID: 28342289 -
Species: Canine
Sample Types: Whole Cells
Applications: BioassayK Sakaguchi et al. (2017), Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells Biochem. Biophys. Res. Commun, 484(1):100-106.
PMID: 28104393 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Ko et al. (2017), Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy Invest. Ophthalmol. Vis. Sci., 58(5):2544-2553.
PMID: 28492873 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Shiokawa et al. (2017), Mesenteric lymph node CD11b(-) CD103(+) PD-L1(High) dendritic cells highly induce regulatory T cells Immunology, 0(0):.
PMID: 28423181 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Zhao et al. (2017), Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota J. Immunol., 0(0):.
PMID: 28539431 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayL Bai et al. (2017), SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells Cell. Signal., 37(0):52-61.
PMID: 28578012 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMA L‚cuyer et al. (2017), Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis Proc. Natl. Acad. Sci. U.S.A, 114(4):E524-E533.
PMID: 28069965 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayF Loayza-Puc et al. (2017), TGF?1-induced leucine limitation uncovered by differential ribosome codon reading EMBO Rep, 0(0):.
PMID: 28274951 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJC Cheng et al. (2017), Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes Sci Rep, 7(1):4448.
PMID: 28667290 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Khakipoor et al. (2017), TGF-? signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes Glia, 0(0):.
PMID: 28568893 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKB McCauley et al. (2017), Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling Cell Stem Cell, 0(0):.
PMID: 28366587 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayP Åström et al. (2017), The interplay of matrix metalloproteinase-8, transforming growth factor-?1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma Br. J. Cancer, 117(7):1007-1016.
PMID: 28772283 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYing Chen et al. (2017), MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. British Journal of Cancer, 0(0):1532-1827.
PMID: 28817834 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayK Kamio et al. (2017), XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts Pulm Pharmacol Ther, 0(0):.
PMID: 28315487 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayH Kusumoto et al. (2017), Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma Cancer Sci., 108(3):528-535.
PMID: 28004467 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChris J C Johnston et al. (2017), A structurally distinct TGF-? mimic from an intestinal helminth parasite potently induces regulatory T cells. Nature Communications, 0(0):2041-1723.
PMID: 29170498 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJ Geng et al. (2017), The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells Nat. Immunol., 0(0):.
PMID: 28504697 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Shibata et al. (2017), Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy PLoS ONE, 12(10):e0186587.
PMID: 29065190 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNisha Bte Mohd Rafiq (2017), Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO J. Cell Biol, 216(1):181-197.
PMID: 28007915 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTsugumi Horikiri (2017), Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia Respir Med, 122(0):43-50.
PMID: 27993290 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Singh et al. (2017), Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells J. Immunol., 0(0):.
PMID: 28455436 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayKH Bae et al. (2017), Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor ? Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice Endocrinol Metab (Seoul), 0(0):.
PMID: 28256116 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayV Ruiz-Carpi et al. (2017), Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients Sci Rep, 7(0):44941.
PMID: 28327551 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Renard et al. (2017), Sex, pregnancy and aortic disease in Marfan syndrome PLoS ONE, 12(7):e0181166.
PMID: 28708846 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Wang et al. (2017), Osteopontin activates mesenchymal stem cells to repair skin wound PLoS ONE, 12(9):e0185346.
PMID: 28957406 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Sasahara et al. (2017), An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells Oncotarget, 8(15):24869-24881.
PMID: 28206960 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayD Brethour et al. (2017), A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition Sci Rep, 7(0):40313.
PMID: 28098160 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShyam Kumar Gudey et al. (2017), Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGF? stimulation in cancer. Oncotarget, 0(0):1949-2553.
PMID: 29228645 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Turcotte et al. (2017), CD73 promotes resistance to HER2/ErbB2 antibody therapy Cancer Res., 0(0):.
PMID: 28855210 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Sato-Matsu et al. (2017), Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling J. Biol. Chem., 0(0):.
PMID: 28916723 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayS Gopal et al. (2017), Fibronectin-guided migration of carcinoma collectives Nat Commun, 8(0):14105.
PMID: 28102238 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayVC Rodríguez- et al. (2017), Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites Sci Rep, 7(1):7594.
PMID: 28790320 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Rynne-Vida et al. (2017), Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer J. Pathol, 0(0):.
PMID: 28247413 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Gamboa Cas et al. (2016), Clustering and jamming in epithelial-mesenchymal co-cultures Soft Matter, 12(40):8327-8337.
PMID: 27722738 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHoeke A Baarsma (2016), Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD J. Exp. Med, 0(0):.
PMID: 27979969 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMohadeseh Mehrabian (2016), Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue PLoS ONE, 11(6):e0156779.
PMID: 27327609 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMartine Schrøder (2016), CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits PLoS ONE, 11(6):e0157387.
PMID: 27311059 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT Nat Commun, 7(0):13362.
PMID: 27869122 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMH Fan et al. (2016), Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice J. Biol. Chem., 291(15):8070-89.
PMID: 26663085 -
(2016), Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci Nat Commun, 7(0):12092.
PMID: 27386823 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKarthikeyan Mythreye (2016), Altering the Proteoglycan State of Transforming Growth Factor ? Type III Receptor (T?RIII)/Betaglycan Modulates Canonical Wnt/?-Catenin Signaling J. Biol. Chem., 291(49):25716-25728.
PMID: 27784788 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBrian G Oliver (2016), A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro Thorax, 71(11):1039-1049.
PMID: 27287090 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Fscn1 is required for the trafficking of TGF-? family type I receptors during endoderm formation Nat Commun, 7(0):12603.
PMID: 27545838 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases Cell Death Dis, 7(12):e2565.
PMID: 28032864 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM F Griffin (2016), Chemical group-dependent plasma polymerisation preferentially directs adipose stem cell differentiation towards osteogenic or chondrogenic lineages Acta Biomater, 0(0):.
PMID: 27956359 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves EBioMedicine, 10(0):282-90.
PMID: 27394642 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTakeshi Suzuki (2016), MEG3 long noncoding RNA contributes to the epigenetic regulation of epithelial-mesenchymal transition in lung cancer cell lines J. Biol. Chem., 0(0):.
PMID: 27852821 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching Sci Rep, 6(0):37215.
PMID: 27853268 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayQisheng Li (2016), Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition Proc Natl Acad Sci USA, 0(0):.
PMID: 27298373 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-?1 in Airway Epithelium PLoS ONE, 11(8):e0162058.
PMID: 27571418 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayClaire Yu (2016), Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion Biomaterials, 120(0):66-80.
PMID: 28038353 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), MAP3K19 Is a Novel Regulator of TGF-? Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis PLoS ONE, 11(5):e0154874.
PMID: 27144281 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySasaki C et al. (2016), p(70S6K1) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice. Eur J Immunol, 46(1):212-22.
PMID: 26514620 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJames B Canavan (2016), Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease Gut, 65(4):584-94.
PMID: 25715355 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis Physiol Rep, 4(17):.
PMID: 27582065 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBharat Vaidyanath (2016), The aryl hydrocarbon receptor controls cell-fate decisions in B cells J. Exp. Med, 0(0):.
PMID: 28011866 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-? Small Molecule Inhibitor Neoplasia, 18(12):795-805.
PMID: 27978994 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis Sci Rep, 6(0):37445.
PMID: 27869174 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShoko Ohno (2016), Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure Sci Rep, 6(0):27192.
PMID: 27273361 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDong-Chuan Guo (2016), Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease Am. J. Hum. Genet, 0(0):.
PMID: 27939641 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Transient RUNX1 Expression during Early Mesendodermal Differentiation of�hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling Stem Cell Reports, 7(5):884-896.
PMID: 27720906 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayR Flynn et al. (2016), Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism Blood, 127(17):2144-54.
PMID: 26983850 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells Cancer Res, 0(0):.
PMID: 27221703 -
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay(2016), 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats PLoS ONE, 11(8):e0161782.
PMID: 27575371 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXiuyun Zeng (2016), TAR DNA-binding protein 43 inhibits inflammatory response and protects chondrocyte function by modulating RACK1 expression in osteoarthritis Biomed. Pharmacother., 0(0):.
PMID: 27890430 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), IL-10 production in murine IgM(+) CD138(hi) cells is driven by Blimp1 and downregulated in class-switched cells Eur. J. Immunol, 0(0):.
PMID: 28012163 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIsabela Pedroza-Pa et al. (2016), Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Scientific Reports, 0(0):2045-2322.
PMID: 26915707 -
Species: Human
Sample Types: Protein
Applications: ELISA (Standard)(2016), Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes Stem Cell Reports, 0(0):.
PMID: 27569062 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMenq-Jer Lee (2016), TGF-?/ SMAD3 Pathway Stimulates Sphingosine-1-phosphate Receptor 3 Expression: Implication of Sphingosine-1-Phosphate Receptor 3 in Lung Adenocarcinoma Progression J. Biol. Chem., 0(0):.
PMID: 27856637 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayA Miyashita et al. (2016), Immunotherapy against Metastatic Melanoma with Human iPS Cell-Derived Myeloid Cell Lines Producing Type I Interferons Cancer Immunol Res, 4(3):248-58.
PMID: 26714554 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Context-Specific Function of S6K2 in Th Cell Differentiation J Immunol, 0(0):.
PMID: 27613697 -
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay(2016), Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin Sci Rep, 6(0):36436.
PMID: 27819314 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Cell-cell contact and matrix adhesion promote ?SMA expression during TGF?1-induced epithelial-myofibroblast transition via Notch and MRTF-A Sci Rep, 6(0):26226.
PMID: 27194451 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySaverio Bellusci (2016), Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis Cell Stem Cell, 0(0):.
PMID: 27867035 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016), Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas PLoS ONE, 11(12):e0167200.
PMID: 28030558 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2016), Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors Clin Cancer Res, 0(0):.
PMID: 27126993 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayIlkow C et al. (2015), Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med, 21(5):530-6.
PMID: 25894825 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHarris T et al. (2015), Drak2 Does Not Regulate TGF-beta Signaling in T Cells. PLoS ONE, 10(5):e0123650.
PMID: 25951457 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKinugasa H et al. (2015), Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene, 34(41):5229-39.
PMID: 25659582 -
Species: Equine
Sample Types: Plasma
Giraldo C et al. (2015), Effects of sodium citrate and acid citrate dextrose solutions on cell counts and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel. BMC Vet Res, 11(0):60.
PMID: 25889052 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRoach K et al. (2015), Lipoxin A4 Attenuates Constitutive and TGF-beta1-Dependent Profibrotic Activity in Human Lung Myofibroblasts. J Immunol, 195(6):2852-60.
PMID: 26276873 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNarcisi R et al. (2015), Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. Stem Cell Reports, 4(3):459-72.
PMID: 25733021 -
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA (Standard)Kaushansky N et al. (2015), Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease. J Biol Chem, 290(24):15260-78.
PMID: 25911099 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoPessina P et al. (2015), Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skelet Muscle, 4(0):7.
PMID: 25157321 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMehrabian M et al. (2015), The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE, 10(8):e0133741.
PMID: 26288071 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYoung K et al. (2015), BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS ONE, 10(4):e0122892.
PMID: 25909848 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySchmitt-Ney M et al. (2015), The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-beta pathway. PLoS ONE, 10(3):e0121474.
PMID: 25806826 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLu G et al. (2015), Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A, 113(5):1256-60.
PMID: 26787905 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySahu S et al. (2015), JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J, 34(16):2162-81.
PMID: 26157010 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang J et al. (2015), Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development. Cancer Res, 75(2):306-15.
PMID: 25492861 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPresnell S et al. (2015), Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs. Genes Immun, 16(1):89-98.
PMID: 25410655 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNguyen L et al. (2015), Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat Immunol, 16(2):207-13.
PMID: 25531831 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNakatsukasa H et al. (2015), The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol, 16(10):1077-84.
PMID: 26322481 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2015), MiR-133 modulates TGF-β1-induced bladder smooth muscle cell hypertrophic and fibrotic response: implication for a role of microRNA in bladder wall remodeling caused by bladder outlet obstruction. Cell Signal, 27(2):215-27.
PMID: 25451078 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRutz S et al. (2015), Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature, 518(7539):417-21.
PMID: 25470037 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLian M et al. (2015), Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-gamma Expression. PLoS ONE, 10(7):e0132741.
PMID: 26177196 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPang M et al. (2015), TGF-beta1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene, 35(6):748-60.
PMID: 25961925 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYu D et al. (2015), The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway. Acta Pharmacol Sin, 36(4):473-82.
PMID: 25832428 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJia D et al. (2015), Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE, 10(3):e0121939.
PMID: 25822822 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKlimatcheva E et al. (2015), CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol, 16(0):6.
PMID: 25879435 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayEun S et al. (2015), 4-1BB ligand signaling to T cells limits T cell activation. J Immunol, 194(1):134-41.
PMID: 25404362 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMasani S et al. (2015), Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination. Proc Natl Acad Sci U S A, 113(5):1261-6.
PMID: 26787901 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySugita S et al. (2015), Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 56(2):1051-62.
PMID: 25604685 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCho W et al. (2015), Suppressor of cytokine signaling 1 is a positive regulator of TGF-beta-induced prostaglandin production in human follicular dendritic cell-like cells. J Immunol, 194(9):4287-97.
PMID: 25825445 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWoltje K et al. (2015), Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells. PLoS ONE, 10(3):e0120547.
PMID: 25799559 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRojas-Fernandez A et al. (2015), Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep, 5(0):9811.
PMID: 25922883 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWoeller C et al. (2015), Salinomycin and other polyether ionophores are a new class of antiscarring agent. J Biol Chem, 290(6):3563-75.
PMID: 25538236 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWaight J et al. (2015), Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans. J Immunol, 194(3):878-82.
PMID: 25548231 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySun et al. (2015), Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J Immunol Res, 2015(0):284215.
PMID: 25918734 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGalvagni F et al. (2015), Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells, 33(3):742-50.
PMID: 25504116 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKuk H et al. (2015), 5Z-7-Oxozeanol Inhibits the Effects of TGFbeta1 on Human Gingival Fibroblasts. PLoS ONE, 10(4):e0123689.
PMID: 25927238 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySingh I et al. (2015), High mobility group protein-mediated transcription requires DNA damage marker gamma-H2AX. Cell Res, 25(7):837-50.
PMID: 26045162 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMu Y et al. (2015), TGFbeta-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells. Br J Cancer, 112(7):1223-31.
PMID: 25756394 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFujita T et al. (2015), Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PLoS ONE, 10(6):e0130808.
PMID: 26110809 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCruet-Hennequart S et al. (2015), Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE, 10(3):e0119334.
PMID: 25837977 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGhiabi P et al. (2015), Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med, 13(0):27.
PMID: 25623554 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMiller C et al. (2014), Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet, 10(3):e1004263.
PMID: 24676100 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPan C et al. (2014), Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. J Biol Chem, 289(37):25486-96.
PMID: 25070888 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHaffner-Luntzer et al. (2014), Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice. PLoS ONE, 9(12):e116282.
PMID: 25551381 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWu Y et al. (2014), COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer. Oncogene, 33(26):3432-40.
PMID: 23934190 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayChen K et al. (2014), The AMPK agonist AICAR inhibits TGF-beta1 induced activation of kidney myofibroblasts. PLoS ONE, 9(9):e106554.
PMID: 25188319 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXu S et al. (2014), Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-beta and induce Tregs development via TGF-beta. PLoS ONE, 9(3):e91709.
PMID: 24638085 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayYu Y et al. (2014), Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation. Mol Med Rep, 9(6):2077-84.
PMID: 24682227 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayUeda J et al. (2014), Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene, 33(36):4485-95.
PMID: 24077287 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTogashi et al. (2014), Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer. Mol Cancer, 13(0):126.
PMID: 24886203 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySalvo E et al. (2014), Combined targeting of TGF-beta1 and integrin beta3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer. Mol Cancer, 13(0):112.
PMID: 24884715 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMidgley A et al. (2014), MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell, 13(2):235-44.
PMID: 24134702 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLiu R et al. (2014), JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol, 44(5):1643-51.
PMID: 24573038 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLi J et al. (2014), The anti-proliferative function of the TGF-beta1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3. J Biol Chem, 289(51):35633-43.
PMID: 25371204 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayZhou Y et al. (2014), Secreted fibroblast-derived miR-34a induces tubular cell apoptosis in fibrotic kidney. J Cell Sci, 127(0):4494-506.
PMID: 25107369 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKarki S et al. (2014), Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis. FASEB J, 28(3):1122-31.
PMID: 24265486 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYao G et al. (2014), MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3. Mol Cell Endocrinol, 382(1):244-53.
PMID: 24145127 -
Species: Human
Sample Types: Whole Cells
Kofler D et al. (2014), Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J Clin Invest, 124(6):2513-22.
PMID: 24812667 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySuresh Babu S et al. (2014), TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer, 14(0):113.
PMID: 24555435 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHan L et al. (2014), The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor gammat (RORgammat) in Th17 cells. J Biol Chem, 289(37):25546-55.
PMID: 25070893 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKumawat K et al. (2014), TGF-beta-activated kinase 1 (TAK1) signaling regulates TGF-beta-induced WNT-5A expression in airway smooth muscle cells via Sp1 and beta-catenin. PLoS ONE, 9(4):e94801.
PMID: 24728340 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChoi S et al. (2014), Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. J Clin Invest, 124(6):2472-82.
PMID: 24837432 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBohnsack R et al. (2014), Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. Invest Ophthalmol Vis Sci, 55(12):7697-708.
PMID: 25358730 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayZheng J et al. (2014), Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis. FEBS J, 281(1):88-103.
PMID: 24138392 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNormanton M et al. (2014), Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE, 9(9):e106673.
PMID: 25184791 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBaldwin A et al. (2014), Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. J Cell Sci, 127(0):158-71.
PMID: 24190885 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTobar N et al. (2014), c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer, 14(0):640.
PMID: 25175743 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen X et al. (2014), Effective chemoimmunotherapy with anti-TGFbeta antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE, 9(1):e85398.
PMID: 24416401 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMercer F et al. (2014), Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors. J Immunol, 193(3):1047-54.
PMID: 24958901 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayQu X et al. (2014), A signal transduction pathway from TGF-beta1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma. J Invest Dermatol, 134(1):159-67.
PMID: 23792459 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFehrholz M et al. (2014), Caffeine and rolipram affect Smad signalling and TGF-beta1 stimulated CTGF and transgelin expression in lung epithelial cells. PLoS ONE, 9(5):e97357.
PMID: 24828686 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKuang D et al. (2014), B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest, 124(10):4657-67.
PMID: 25244097 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOkada Y et al. (2014), TRPA1 is required for TGF-beta signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma. Lab Invest, 94(9):1030-41.
PMID: 25068659 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJakobsen R et al. (2014), Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE, 9(5):e96615.
PMID: 24816923 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChen L et al. (2014), Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines. PLoS ONE, 9(7):e101040.
PMID: 24983967 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPrigent L et al. (2014), The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation. Eur J Immunol, 44(5):1330-40.
PMID: 24549985 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRojo J et al. (2014), Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo. J Leukoc Biol, 95(3):441-50.
PMID: 24212096 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRatnayake M et al. (2014), Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE, 9(1):e86590.
PMID: 24466161 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKongsbak M et al. (2014), Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE, 9(5):e96695.
PMID: 24792400 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKomatsu N et al. (2014), Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med, 20(1):62-8.
PMID: 24362934 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayShi X et al. (2014), TGF-beta/Smad3 stimulates stem cell/developmental gene expression and vascular smooth muscle cell de-differentiation. , 9(0):.
PMID: 24718260 -
Species: Human
Sample Types: Whole Cells
Applications: Cell CultureKim D et al. (2014), Gene expression profiles of human adipose tissue-derived mesenchymal stem cells are modified by cell culture density. PLoS ONE, 9(1):e83363.
PMID: 24400072 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLuo F et al. (2014), Arsenic trioxide inhibits transforming growth factor-beta1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. Respir Res, 15(0):51.
PMID: 24762191 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayXiao et al. (2014), Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE, 9(9):e106538.
PMID: 25198549 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKirkegaard T et al. (2014), The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines. Int J Oncol, 45(1):393-400.
PMID: 24819550 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOlderoy M et al. (2014), Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels. PLoS ONE, 9(3):e91662.
PMID: 24626259 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGordian E et al. (2014), Transforming growth factor beta signaling overcomes dasatinib resistance in lung cancer. PLoS ONE, 9(12):e114131.
PMID: 25501935 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySchwartze J et al. (2014), Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-beta signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts. J Biol Chem, 289(6):3262-75.
PMID: 24347165 -
Overstreet J et al. (2014), Redox control of p53 in the transcriptional regulation of TGF-beta1 target genes through SMAD cooperativity. Cell Signal, 26(7):1427-36.
PMID: 24613410 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRozycki M et al. (2014), The fate of the primary cilium during myofibroblast transition. Mol Biol Cell, 25(5):643-57.
PMID: 24403605 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWei D et al. (2014), Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing. PLoS Pathog, 10(4):e1004071.
PMID: 24722454 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLiu Y et al. (2014), Inhibition by all-trans-retinoic acid of transforming growth factor-beta-induced collagen gel contraction mediated by human tenon fibroblasts. Invest Ophthalmol Vis Sci, 55(7):4199-205.
PMID: 24894398 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGallo E et al. (2014), Angiotensin II-dependent TGF-beta signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest, 124(1):448-60.
PMID: 24355923 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMatsuhashi S et al. (2014), Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells. Cell Signal, 26(3):603-10.
PMID: 24334270 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHardin H et al. (2014), The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. Am J Pathol, 184(8):2342-54.
PMID: 24946010 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNeumann C et al. (2014), Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med, 211(9):1807-19.
PMID: 25073792 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZafar A et al. (2014), Chromatinized protein kinase C-theta directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Mol Cell Biol, 34(16):2961-80.
PMID: 24891615 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayChen C et al. (2014), Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol Med, 6(3):322-34.
PMID: 24401839 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTulley S et al. (2014), Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-beta signaling. J Biol Chem, 289(22):15280-96.
PMID: 24727589 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHou S et al. (2014), Follicular dendritic cell secreted protein FDC-SP controls IgA production. Mucosal Immunol, 7(4):948-57.
PMID: 24399151 -
Species: Feline
Sample Types: Whole Cells
Applications: BioassayMiller M et al. (2014), CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGFbeta / GARP-mediated mechanism. Virol J, 11(0):7.
PMID: 24438223 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang X et al. (2014), Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF-beta signaling pathway. Int J Oncol, 44(4):1099-106.
PMID: 24452274 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySolomon J et al. (2014), VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol Cancer Res, 12(8):1166-80.
PMID: 24825850 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayArts M et al. (2014), Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor. PLoS ONE, 9(6):e100035.
PMID: 24927197 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoAcuna M et al. (2014), Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-beta signalling. Hum Mol Genet, 23(5):1237-49.
PMID: 24163134 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGobel K et al. (2014), Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. Eur J Immunol, 44(8):2295-305.
PMID: 24811005 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDesai L et al. (2014), Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein. J Biol Chem, 289(26):18270-8.
PMID: 24831009 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLim M et al. (2014), Induction of galectin-1 by TGF-beta1 accelerates fibrosis through enhancing nuclear retention of Smad2. Exp Cell Res, 326(1):125-35.
PMID: 24928277 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDiepenbruck et al. (2014), Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition. J Cell Sci, 127(0):1523-36.
PMID: 24554433 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGao X et al. (2014), Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS ONE, 9(2):e89114.
PMID: 24586530 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJolly L et al. (2014), Influenza promotes collagen deposition via alphavbeta6 integrin-mediated transforming growth factor beta activation. J Biol Chem, 289(51):35246-63.
PMID: 25339175 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBrady K et al. (2014), Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev, 23(5):541-54.
PMID: 24172175 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAxpe E et al. (2014), Detection of atomic scale changes in the free volume void size of three-dimensional colorectal cancer cell culture using positron annihilation lifetime spectroscopy. PLoS ONE, 9(1):e83838.
PMID: 24392097 -
Species: Feline
Sample Types: Whole Cells
Applications: BioassayJeon K et al. (2014), Inhibitory effects of PPARgamma ligands on TGF-beta1-induced corneal myofibroblast transformation. Am J Pathol, 184(5):1429-45.
PMID: 24650561 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAschner Y et al. (2014), Protein tyrosine phosphatase alpha mediates profibrotic signaling in lung fibroblasts through TGF-beta responsiveness. Am J Pathol, 184(5):1489-502.
PMID: 24650563 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMatthews A et al. (2014), Binding of AID to DNA does not correlate with mutator activity. J Immunol, 193(1):252-7.
PMID: 24879790 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCheng T et al. (2014), Transforming growth factor-beta-induced miR143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo. Int J Oncol, 45(5):1977-88.
PMID: 25175415 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKudo-Saito C et al. (2014), Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Res, 74(5):1361-70.
PMID: 24590808 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPark S et al. (2014), Musashi-2 controls cell fate, lineage bias, and TGF-beta signaling in HSCs. J Exp Med, 211(1):71-87.
PMID: 24395885 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLi H et al. (2014), Independent adipogenic and contractile properties of fibroblasts in Graves' orbitopathy: an in vitro model for the evaluation of treatments. PLoS ONE, 9(4):e95586.
PMID: 24751986 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySanthekadur P et al. (2014), Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling. FEBS Open Bio, 4(0):353-61.
PMID: 24918049 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayItaliani et al. (2014), Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS ONE, 9(2):e87680.
PMID: 24498352 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOkabe H et al. (2014), Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma. PLoS ONE, 9(6):e98817.
PMID: 24892551 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMael-Ainin M et al. (2014), Inhibition of periostin expression protects against the development of renal inflammation and fibrosis. J Am Soc Nephrol, 25(8):1724-36.
PMID: 24578131 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLoureiro J et al. (2013), Tamoxifen ameliorates peritoneal membrane damage by blocking mesothelial to mesenchymal transition in peritoneal dialysis. PLoS ONE, 8(4):e61165.
PMID: 23637793 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayYasmin N et al. (2013), Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J Exp Med, 210(12):2597-610.
PMID: 24190429 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang X et al. (2013), TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses. J Immunol, 191(11):5420-9.
PMID: 24140642 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCheng J et al. (2013), Transforming growth factor-beta1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein. J Biol Chem, 288(46):33181-92.
PMID: 24106276 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTruchetet M et al. (2013), Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement. Arthritis Rheum, 65(5):1347-56.
PMID: 23335253 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYanaba K et al. (2013), Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. J Leukoc Biol, 94(4):563-73.
PMID: 23630391 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMae et al. (2013), Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun, 4(0):1367.
PMID: 23340407 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayHojo et al. (2013), Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium. J Biol Chem, 288(14):9924-32.
PMID: 23423383 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNasarre P et al. (2013), Neuropilin-2 Is upregulated in lung cancer cells during TGF-beta1-induced epithelial-mesenchymal transition. Cancer Res, 73(23):7111-21.
PMID: 24121493 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayXu Z et al. (2013), Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-beta1 and platelet-derived growth factor BB. Mol Med Rep, 8(6):1715-21.
PMID: 24084832 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHung C et al. (2013), Role of IGF-1 pathway in lung fibroblast activation. Respir Res, 14(0):102.
PMID: 24103846 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAmmann J et al. (2013), Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J Immunol, 190(10):5030-6.
PMID: 23589618 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayO'Connor J et al. (2013), Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling. PLoS ONE, 8(12):e83188.
PMID: 24340092 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhou Q et al. (2013), In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo. Cytokine, 65(1):56-64.
PMID: 24080164 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTannetta D et al. (2013), Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin. PLoS ONE, 8(2):e56754.
PMID: 23437230 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKeune W et al. (2013), Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression. Cancer Res, 73(23):6913-25.
PMID: 24127122 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2013), Transforming growth factor β-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis. Am J Pathol, 182(1):118-31.
PMID: 23142380 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayGu L et al. (2013), Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential. Lab Invest, 93(4):450-61.
PMID: 23439432 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShinojima N et al. (2013), TGF-beta mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells. Cancer Res, 73(7):2333-44.
PMID: 23365134 -
Species: Mouse
Sample Types: Tissue Homogenates
Applications: BioassayGotz A et al. (2013), Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70. PLoS ONE, 8(3):e60642.
PMID: 23544157 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayStephens G et al. (2013), Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands. Eur J Immunol, 43(7):1727-34.
PMID: 23568529 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayOliveira W et al. (2013), The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of human tegumentary leishmaniasis. Cytokine, 66(2):127-32.
PMID: 24485388 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMasani et al. (2013), Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination. Mol Cell Biol, 33(7):1468-73.
PMID: 23382073 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySerrano et al. (2013), Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun, 4(0):2976.
PMID: 24356468 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWang C et al. (2013), Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells. J Clin Invest, 123(4):1677-93.
PMID: 23478407 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySun H et al. (2013), Expression regulation of co-inhibitory molecules on human natural killer cells in response to cytokine stimulations. Cytokine, 65(1):33-41.
PMID: 24139237 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLong et al. (2013), MicroRNA-22 is a master regulator of bone morphogenetic protein-7/6 homeostasis in the kidney. J Biol Chem, 288(51):36202-14.
PMID: 24163368 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayRamdas V et al. (2013), Canonical transforming growth factor-beta signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29. Am J Pathol, 183(6):1885-96.
PMID: 24103556 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu Y et al. (2013), MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms. Oncogene, 32(3):296-306.
PMID: 22370643 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKinashi H et al. (2013), TGF-beta1 promotes lymphangiogenesis during peritoneal fibrosis. J Am Soc Nephrol, 24(10):1627-42.
PMID: 23990681 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPark J et al. (2013), FOG2 protein down-regulation by transforming growth factor-beta1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy. J Biol Chem, 288(31):22469-80.
PMID: 23788640 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLeung L et al. (2013), Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis. PLoS ONE, 8(12):e84366.
PMID: 24386371 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen et al. (2013), H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 45(1):34-42.
PMID: 23202127 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayLiu M et al. (2013), TGF-beta1 regulation of estrogen production in mature rat Leydig cells. PLoS ONE, 8(3):e60197.
PMID: 23555924 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLin Y et al. (2013), JNK inhibitor SP600125 enhances TGF-beta-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner. Mol Med Rep, 8(6):1623-9.
PMID: 24100678 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGeng L et al. (2013), TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis. PLoS ONE, 8(3):e59918.
PMID: 23536895 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBalli D et al. (2013), Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. EMBO J, 32(2):231-44.
PMID: 23288041 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayNguyen H et al. (2013), Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture. Cancer Cell Int, 13(1):16.
PMID: 23409704 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayTammaro A et al. (2013), Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy. PLoS ONE, 8(12):e82498.
PMID: 24358193 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRomero D et al. (2013), Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-beta/Smad signalling. J Cell Sci, 126(0):1858-67.
PMID: 23444370 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayScherz-Shouval R et al. (2013), The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell, 158(3):564-78.
PMID: 25083868 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHanieh H et al. (2013), MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration. Eur J Immunol, 43(10):2771-82.
PMID: 23780851 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLi J et al. (2012), Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients. J Biol Chem, 287(42):35484-95.
PMID: 22893706 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRadulovic K et al. (2012), CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential. J. Immunol., 188(4):2001-13.
PMID: 22250092 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayFlanagan K et al. (2012), Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS. PLoS ONE, 7(7):e40443.
PMID: 22792325 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012), Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis. J. Exp. Med., 209(11):2033-47.
PMID: 23071254 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoNakasone Y et al. (2012), Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma. Am. J. Pathol., 180(1):365-74.
PMID: 22037251 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassay(2012), Progenitor-like traits contribute to patient survival and prognosis in oligodendroglial tumors. Clin. Cancer Res., 18(15):4122-35.
PMID: 22675171 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCasey KA et al. (2012), Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J. Immunol., 188(10):4866-75.
PMID: 22504644 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDupuy S et al. (2012), Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog., 8(1):e1002486.
PMID: 22253598 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCerchia et al. (2012), Targeting Axl with an high-affinity inhibitory aptamer. Mol Ther, 20(12):2291-303.
PMID: 22910292 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayWilson TR et al. (2012), Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 487(7408):505-9.
PMID: 22763448 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHuse K et al. (2012), Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma. PLoS ONE, 7(10):e46117.
PMID: 23049692 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAbushahba W et al. (2012), Non-Canonical Smads Phosphorylation Induced by the Glutamate Release Inhibitor, Riluzole, through GSK3 Activation in Melanoma. PLoS ONE, 7(10):e47312.
PMID: 23077590 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassaySohni A et al. (2012), TGF beta1-Induced Baf60c Regulates both Smooth Muscle Cell Commitment and Quiescence. PLoS ONE, 7(10):e47629.
PMID: 23110084 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayCorvaisier M et al. (2012), IL-26 Is Overexpressed in Rheumatoid Arthritis and Induces Proinflammatory Cytokine Production and Th17 Cell Generation. PLoS Biol, 10(9):e1001395.
PMID: 23055831 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKudo et al. (2012), Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis. J Biol Chem, 287(46):38716-28.
PMID: 22992737 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBruce D et al. (2012), Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-beta pathway. Cell Signal, 24(11):1999-2006.
PMID: 22781750 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012), Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat. Med., 1248(0):18.
PMID: 22772464 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNam D et al. (2012), T-Lymphocytes Enable Osteoblast Maturation via IL-17F during the Early Phase of Fracture Repair. PLoS ONE, 7(6):e40044.
PMID: 22768215 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGrubisha MJ et al. (2012), A Local Paracrine and Endocrine Network Involving TGF beta, Cox-2, ROS, and Estrogen Receptor beta Influences Reactive Stromal Cell Regulation of Prostate Cancer Cell Motility. Mol. Endocrinol., 26(6):940-54.
PMID: 22593181 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPignatelli J et al. (2012), Hic-5 promotes invadopodia formation and invasion during TGF-beta-induced epithelial-mesenchymal transition. J. Cell Biol., 197(3):421-37.
PMID: 22529104 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKrishnan A et al. (2012), Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis. Lab Invest, 92(12):1712-25.
PMID: 23007134 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMottershead D et al. (2012), Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15. Mol Hum Reprod, 18(3):121-8.
PMID: 21911477 -
Species: N/A
Sample Types: N/A
Applications: ELISA (Standard)Liu F et al. (2011), C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes. Diabetologia, 54(10):2713-23.
PMID: 21744073 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPeressin M et al. (2011), HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies. J. Virol., 85(2):1077-85.
PMID: 21084491 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayGibbings S et al. (2011), Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha. J. Biol. Chem., 286(2):961-75.
PMID: 21059659 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYilmaz M et al. (2011), Transcription factor Dlx2 protects from TGFbeta-induced cell-cycle arrest and apoptosis. EMBO J., 30(21):4489-99.
PMID: 21897365 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayEl-Behi M et al. (2011), The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat. Immunol., 12(6):568-75.
PMID: 21516111 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBourne GL et al. (2011), Development and characterisation of an assay for furin activity. J. Immunol. Methods, 364(1):101-8.
PMID: 21112328 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEisenwort G et al. (2011), Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-beta1-dependent human epidermal Langerhans cells. J. Invest. Dermatol., 131(10):2049-57.
PMID: 21677668 -
Species: Equine
Sample Types: Whole Cells
Applications: BioassayLey C et al. (2011), Effects of high mobility group box protein-1, interleukin-1beta, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures. Connect. Tissue Res., 52(4):290-300.
PMID: 21117899 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMa Y et al. (2011), Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J. Exp. Med., 208(3):491-503.
PMID: 21383056 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHenriksson ML et al. (2011), Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion. Am. J. Pathol., 178(3):1387-94.
PMID: 21356388 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKashiwada M et al. (2011), NFIL3/E4BP4 controls type 2 T helper cell cytokine expression. EMBO J., 30(10):2071-82.
PMID: 21499227 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJones GW et al. (2011), Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J., 25(1):409-19.
PMID: 20826539 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNakahama T et al. (2011), Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis. Proc. Natl. Acad. Sci. U.S.A., 108(34):14222-7.
PMID: 21825138 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoYamazaki S et al. (2011), Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell, 147(5):1146-58.
PMID: 22118468 -
Sierra-Filardi E et al. (2011), Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood, 117(19):5092-101.
PMID: 21389328 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDuchez S et al. (2011), Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation. Eur. J. Immunol., 41(12):3632-44.
PMID: 22076801 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDavis-Dusenbery BN et al. (2011), Down-regulation of Kruppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-{beta} and Bone Morphogenetic Protein 4. J. Biol. Chem., 286(32):28097-110.
PMID: 21673106 -
Species: Canine
Sample Types: Whole Cells
Applications: BioassayGregory PA et al. (2011), An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol. Biol. Cell, 22(10):1686-98.
PMID: 21411626 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJin W et al. (2011), The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol., 12(0):68.
PMID: 22182253 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKato N et al. (2011), Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. Am. J. Pathol., 178(2):572-9.
PMID: 21281789 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHoffman AM et al. (2011), Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung. Stem Cells Dev., 20(10):1779-92.
PMID: 21585237 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDePaolo RW et al. (2011), Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature, 471(7337):220-4.
PMID: 21307853 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayZheng L et al. (2011), Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS ONE, 6(4):e19390.
PMID: 21572519 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBoswell S et al. (2011), Induction of latency-associated peptide (transforming growth factor-beta(1)) expression on CD4+ T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-alpha production in a transforming growth factor-beta-dependent manner. Immunology, 133(3):278-87.
PMID: 21426338 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayElkabets M et al. (2011), Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J. Clin. Invest., 121(2):784-99.
PMID: 21266779 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayTan C et al. (2010), Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J. Immunol., 185(11):6795-801.
PMID: 20971929 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayRai D et al. (2010), Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Proc. Natl. Acad. Sci. U.S.A., 107(7):3111-6.
PMID: 20133617 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChang HC et al. (2010), The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat. Immunol., 11(6):527-34.
PMID: 20431622 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMoransard M et al. (2010), Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia, 58(5):559-71.
PMID: 19941340 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBohr W et al. (2010), Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein. PLoS ONE, 5(12):e16000.
PMID: 21209863 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKrueger C et al. (2010), Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. PLoS ONE, 5(11):e15511.
PMID: 21152098 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen G et al. (2010), Regulation of the IL-21 gene by the NF-kappaB transcription factor c-Rel. J. Immunol., 185(4):2350-9.
PMID: 20639489 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMaupin KA et al. (2010), Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems. PLoS ONE, 5(9):e13002.
PMID: 20885998 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayJindra C (2010), Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. Eur J Immunol, 40(2):321-9.
PMID: 19950173 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLee WW et al. (2010), Regulating human Th17 cells via differential expression of IL-1 receptor. Blood, 115(3):530-40.
PMID: 19965648 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYoshizaki A et al. (2010), Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J. Immunol., 185(4):2502-15.
PMID: 20624949 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJones GW et al. (2010), Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J. Immunol., 184(4):2130-9.
PMID: 20083667 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu X et al. (2010), Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease. Nat. Med., 16(2):191-7.
PMID: 20062065 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMorizane S et al. (2010), Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J. Invest. Dermatol., 130(5):1297-306.
PMID: 20090765 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySuzuki K et al. (2010), The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity, 33(1):71-83.
PMID: 20643338 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayRoux J et al. (2010), Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. J. Biol. Chem., 285(7):4278-90.
PMID: 19996317 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMiyake T et al. (2010), Nuclear function of Smad7 promotes myogenesis. Mol. Cell. Biol., 30(3):722-35.
PMID: 19995910 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBoenisch O et al. (2010), TIM-3: a novel regulatory molecule of alloimmune activation. J. Immunol., 185(10):5806-19.
PMID: 20956339 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayStockis J et al. (2009), Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg. Eur. J. Immunol., 39(12):3315-22.
PMID: 19750484 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPedroja BS et al. (2009), Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling. J. Biol. Chem., 284(0):20708.
PMID: 19487690 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHan Y et al. (2009), CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J. Immunol., 182(1):111-20.
PMID: 19109141 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySehrawat S et al. (2009), Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators. J. Immunol., 182(5):3191-201.
PMID: 19234217 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDuhen T et al. (2009), Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol., 10(8):857-63.
PMID: 19578369 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDuluc D et al. (2009), Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int. J. Cancer, 125(2):367-73.
PMID: 19378341 -
Species: N/A
Sample Types: N/A
Applications: Western BlotVitsky A et al. (2009), Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues. Am. J. Pathol., 174(6):2137-49.
PMID: 19406991 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayShi S et al. (2009), Growth factor regulation of growth factors in articular chondrocytes. J. Biol. Chem., 284(11):6697-704.
PMID: 19136669 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShafer SL et al. (2009), Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J. Mol. Cell. Cardiol., 46(5):621-35.
PMID: 19344627 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKinoshita H et al. (2009), Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol., 123(1):179-86.
PMID: 19056108 -
Species: Human
Sample Types: Whole Cells
Applications: BioassaySugiura H et al. (2009), Activation of Toll-like receptor 3 augments myofibroblast differentiation. Am. J. Respir. Cell Mol. Biol., 40(6):654-62.
PMID: 18988918 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAlbanesi C et al. (2009), Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J. Exp. Med., 206(1):249-58.
PMID: 19114666 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBoniface K et al. (2009), Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med., 206(3):535-48.
PMID: 19273625 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMargulis A et al. (2009), Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J. Immunol., 183(3):1739-50.
PMID: 19592653 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNolan-Stevaux O et al. (2009), GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev., 23(1):24-36.
PMID: 19136624 -
Species: Human
Sample Types: Whole Cells
Applications: Bioassayvan Steensel L et al. (2009), Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy. Invest. Ophthalmol. Vis. Sci., 50(7):3091-8.
PMID: 19234339 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAmiable N et al. (2009), Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone, 44(6):1143-50.
PMID: 19264156 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoBhowmick S et al. (2009), Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection. Infect. Immun., 77(4):1514-23.
PMID: 19168736 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDuraisingham SS et al. (2009), TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses. J. Immunol., 183(4):2242-51.
PMID: 19625644 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayVeraldi KL et al. (2009), Role of insulin-like growth factor binding protein-3 in allergic airway remodeling. Am. J. Respir. Crit. Care Med., 180(7):611-7.
PMID: 19608721 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAliahmadi E et al. (2009), TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur. J. Immunol., 39(5):1221-30.
PMID: 19350551 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayDai Z et al. (2009), Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J. Exp. Med., 206(4):793-805.
PMID: 19289577 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayEid RE et al. (2009), Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 119(10):1424-32.
PMID: 19255340 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayLamba S et al. (2009), Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism. Glia, 57(9):971-7.
PMID: 19062179 -
Species: Equine
Sample Types: Whole Cells
Applications: BioassayReed SA et al. (2008), Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types. J. Cell. Physiol., 215(2):329-36.
PMID: 17929245 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOhba T et al. (2008), A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs. Arthritis Rheum., 58(11):3510-9.
PMID: 18975342 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayKuchtey J et al. (2008), Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor. Invest. Ophthalmol. Vis. Sci., 49(8):3438-48.
PMID: 18421092 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySheng MH et al. (2008), Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity. FEBS Lett., 582(10):1451-8.
PMID: 18381073 -
Species: Rabbit
Sample Types: In Vivo
Applications: In VivoAnderson BC et al. (2008), Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest. Ophthalmol. Vis. Sci., 49(1):221-9.
PMID: 18172096 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCox CA et al. (2008), Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. J. Immunol., 180(11):7414-22.
PMID: 18490741 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShinohara ML et al. (2008), Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity, 29(1):68-78.
PMID: 18619869 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHaydont V et al. (2008), Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-beta1. Am. J. Physiol., Cell Physiol., 294(6):C1332-41.
PMID: 18400984 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayMarsh D et al. (2008), alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. Cancer Res., 68(9):3295-303.
PMID: 18451156 -
Species: Rat
Sample Types: Aqueous Humor
Applications: BioassayKe Y et al. (2008), Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis. Invest. Ophthalmol. Vis. Sci., 49(9):3999-4007.
PMID: 18487362 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayPittet P et al. (2008), Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds. J. Cell. Sci., 121(0):877-86.
PMID: 18303045 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayWalsh MF et al. (2008), Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via smad- and p38-dependent mechanisms. Am. J. Pathol., 173(2):385-99.
PMID: 18583311 -
Species: Rat
Sample Types: Whole Cells
Applications: BioassayTsoporis JN et al. (2008), Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha. J. Biol. Chem., 283(44):30174-83.
PMID: 18753141 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGuo B et al. (2008), The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest., 118(5):1680-90.
PMID: 18382764 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayPen A et al. (2008), Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling. Oncogene, 27(54):6834-44.
PMID: 18711401 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayHerman S et al. (2008), Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis. Arthritis Rheum., 58(10):3041-50.
PMID: 18821671 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMuranski P et al. (2008), Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood, 112(2):362-73.
PMID: 18354038 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayAoudjehane L et al. (2008), Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway. Lab. Invest., 88(9):973-85.
PMID: 18626468