Skip to main content

Recombinant Human TGF-beta 1 Protein

An alternative TGF-beta 1 is now available! 7754-BH is Hek293 expressed
(3)
(3)
(3)
R&D Systems Guarantee

Product Performance Pledge

We offer a 100% guarantee on all our products.

Learn More »

Key Product Details

Source: CHO
Accession #: P01137
Structure / Form: Disulfide-linked homodimer
Applications: Bioactivity

Complete Your Experiment

Complete Your Research

Showing 1-5 of 654 citations
Filter By:

Citations (654)

Citations are publications that use Bio-techne products. Selected citations for Recombinant Human TGF-beta 1 Protein include:

There are no citations that match your criteria.

Customer Reviews

4.7 out of 5
46 customer ratings
5 stars
67%
4 stars
33%
3 stars
0%
2 stars
0%
1 star
0%
Showing 1-5 of 46 reviews
Filter By:
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 16th Nov 2020
    Application: Immunoassay Standard
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 28th Oct 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 8th Oct 2020
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 7th Oct 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 2nd Jul 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 26th Jun 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 6th Jun 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 23rd May 2020
    Application: CellProlif
    Recombinant Human TGF-beta 1 Protein Cell Proliferation 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 16th May 2020
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 20th Apr 2020
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 6th Mar 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 8th Jan 2020
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 9th Oct 2019
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 10th Sep 2019
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 29th Aug 2019
    Application: Immunoassay Standard
    Recombinant Human TGF-beta 1 Protein Immunoassay Standard 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 21st Aug 2019
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 15th Feb 2019
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 31st Jan 2019
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 17th Dec 2018
    Application: In vitro bioactivity in cell culture
    Use SMAD reporter to test TGF-beta response in cell culture.
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 7th Nov 2018
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 8th Oct 2018
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 22nd Sep 2018
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 20th Aug 2018
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 20th Aug 2018
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 30th Jul 2018
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 15th Jun 2018
    Application: Cell Adhesion
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 18th Apr 2018
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 28th Mar 2018
    Application: Binding assay/Protein-protein interaction
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 24th Jan 2018
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 5th Jan 2018
    Application: Immunoassay Standard
    This protein was used as the standard in an ELISA with antibodies MAB240 and BAF240.
    Recombinant Human TGF-beta 1 Protein Immunoassay Standard 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 1st Dec 2017
    Application: Binding assay/Protein-protein interaction
    They work awesome
    Recombinant Human TGF-beta 1 Protein Binding assay/Protein-protein interaction 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 11th Sep 2017
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 30th Aug 2017
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 17th May 2017
    Application: Media additive for protein or antibody production
    EMT was induced in PANC1 using TGF beta. EMT markers at both protein and mRNA level were examined using RT PCR and WB. Typical markers of EMT was seen to be altered after TGFbeta treatment in accordance to the desired effect which is induction of EMT
    Recombinant Human TGF-beta 1 Protein Media additive for protein or antibody production 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 2nd May 2017
    Application: Stem/Immune cell maintenance or differentiation
    Product used for differentiation of human FOXP3+ cells (regulatory T cells, Tregs) from naive CD4+ T cells, within different experimental setups. You may add these papers to the references for this product. We name the product in these papers: Éliás S, Schmidt A, Kannan V, Andersson J, Tegnér J (2016): TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner. Frontiers in Immunology 2016 Dec 23;7:603. doi: 10.3389/fimmu.2016.00603. PMID: 28066414. Schmidt A, Éliás S, Joshi RN, Tegnér J (2016): In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-beta -containing Protocol. Journal of Visualized Experiments 2016 Dec 30;(118). doi: 10.3791/55015. PMID: 28060341. Schmidt A, Zhang XM, Joshi RN, Iqbal S, Wahlund C, Gabrielsson S, Harris R, Tegnér J (2016): Human macrophages induce CD4+Foxp3+ regulatory T cells via binding and re-release of TGF-beta. Immunology & Cell Biology Sep;94(8):747-62. doi: 10.1038/icb.2016.34. PMID: 27075967.Schmidt A, Eriksson M, Shang MM, Weyd H, Tegnér J (2016): Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate. PLoS ONE 11(2), e0148474. doi:10.1371/journal.pone.0148474. PMID: 26886923.
    Recombinant Human TGF-beta 1 Protein Stem/Immune cell maintenance or differentiation  240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 14th Apr 2017
    Application: T cell differentiation
    Naive mouse T cells were stimulated with anti-CD3e, anti-CD28, IL-2, and human TGF-beta. Four days later, Foxp3 induction was assessed by intracellular flow cytometry.
    Recombinant Human TGF-beta 1 Protein T cell differentiation 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 20th Feb 2017
    Application: fibroblast-to-myofibroblast differentiation
    TGF-beta stimulation of primary murine lung fibroblasts
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 8th Aug 2016
    Application: In vitro bioactivity in cell culture
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 23rd Jul 2016
    Application: Stem/Immune cell maintenance or differentiation
    Recombinant Human TGF-beta 1 Protein Stem/Immune cell maintenance or differentiation  240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 21st Jul 2016
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 21st Jul 2016
    Application: In vitro bioactivity in cell culture
    Recombinant Human TGF-beta 1 Protein In vitro bioactivity in cell culture 240-B
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 12th May 2016
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 12th May 2016
    Application: Cell migration/motility
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 12th May 2016
    Application: CellProlif
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 13th Jan 2016
    Application: we use it to prepare Metsr medium.
  • Recombinant Human TGF-beta 1 Protein
    Name: Anonymous | 13th Jan 2016
    Application: In vitro bioactivity in cell culture

There are no reviews that match your criteria.

FAQs

  • Will Recombinant Human TGF-beta 1 support the maintenance of either human or non-human cultured cells?

    TGF-beta 1 performs multiple cellular functions, including cell growth, proliferation, differentiation and apoptosis.  It would be necessary to determine the specific conditions for cell growth/proliferation for the cells being cultured.

  • Can Recombinant Human TGF beta 1 Protein (Catalog # 240-B or 240-B/CF) be reconstituted in PBS or water?

    Recombinant Human TGF beta 1 Protein (Catalog # 240-B or 240-B/CF) needs to be reconstituted to 100 μg/mL in sterile 4 mM HCl containing 0.1% BSA or 4 mM HCl. This protein is hydrophobic by nature, so it requires an acidic buffer for reconstitution to go completely into solution. Stability testing has been evaluated on the protein with these reconstitution conditions; we can guarantee performance under these reconstitution conditions. When the protein is diluted with the cell culture media or buffers to the working concentration, the concentration of the acid should be buffered or negligible.

  • Has the half-life of recombinant human TGF beta 1 been determined?

    While our Recombinant Human TGF-beta 1 Protein has been evaluated for bioactivity, the half-life of a specific protein will depend on experimental conditions, including the cell number, density, and media content. It is up to the end-user to determine the appropriate concentration and timing when adding Recombinant Human TGF-beta 1 Protein to individual experiments. For techniques and methodologies, we recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.