TGF-beta 1/1.2 Antibody
R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Immunogen: |
Chinese hamster ovary cell line CHO-derived recombinant human TGF‑ beta 1 Ala279-Ser390 Accession # P01137 |
Applications: | Block/Neutralize, Western Blot |
Label: | Unconjugated |
Source: | Polyclonal Chicken IgY |
Specificity: |
Detects TGF-beta 1/1.2 in direct ELISAs and Western blots. |
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Citations for TGF-beta 1/1.2 Antibody (29)
Citations are publications that use Bio-Techne products. Selected citations for TGF-beta 1/1.2 Antibody include:
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Species: Mouse
Sample Types: Whole Cells
Applications: BioassayI Paredes et al. (2021), Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk Nature Neuroscience, 0(0).
PMID: 33510480 -
Species: Rat
Sample Types: In Vivo
Applications: In VivoMAA Mahdy et al. (2020), Neutralization of transforming growth factor (TGF)-&beta1 activity reduced fibrosis and enhanced regeneration of glycerol-injured rat muscle J. Vet. Med. Sci., 82(2):168-171.
PMID: 31875598 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationM Paku?a et al. (2020), Deciphering the Molecular Mechanism of Spontaneous Senescence in Primary Epithelial Ovarian Cancer Cells Cancers (Basel), 12(2).
PMID: 32012719 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationM Paku?a et al. (2019), The Epithelial-Mesenchymal Transition Initiated by Malignant Ascites Underlies the Transmesothelial Invasion of Ovarian Cancer Cells Int J Mol Sci, 20(1).
PMID: 30609691 -
Species: Mink
Sample Types: Whole Cells
Applications: NeutralizationS Holvoet et al. (2019), Oral Tolerance Induction to Newly Introduced Allergen is Favored by a Transforming Growth Factor-beta-Enriched Formula Nutrients, 11(9).
PMID: 31540231 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationM Paku?a et al. (2019), A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer Cancers (Basel), 11(5).
PMID: 31086083 -
Species: Human
Sample Types: Platelet Rich Plasma (PRP)
Applications: ImmunoprecipitationO Miroshnych et al. (2017), The Use of Platelet-Rich and Platelet-Poor Plasma to Enhance Differentiation of Skeletal Myoblasts: Implications for the Use of Autologous Blood Products for Muscle Regeneration Am J Sports Med, 45(4):945-953.
PMID: 28027451 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCZhang P et al. (2015), Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment. Sci Rep, 5(0):8919.
PMID: 25747469 -
Species: Mouse
Sample Types: Whole Cells
Applications: NeutralizationYeste A et al. (2014), IL-21 induces IL-22 production in CD4+ T cells. Nat Commun, 5(0):3753.
PMID: 24796415 -
Species: Rat
Sample Types: Whole Cells
Applications: NeutralizationKang I et al. (2014), Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor beta (TGFbeta)-, epidermal growth factor (EGF)-, and nuclear factor kappaB (NFkappaB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion. J Biol Chem, 289(22):15393-404.
PMID: 24719328 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: ImmunoprecipitationWiener Z et al. (2014), Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta. Proc Natl Acad Sci U S A, 111(21):E2229-36.
PMID: 24825889 -
Species: Rat
Sample Types: Whole Tissue
Applications: IHCDaniel C et al. (2013), Long-term gene therapy with thrombospondin 2 inhibits TGF-beta activation, inflammation and angiogenesis in chronic allograft nephropathy. PLoS ONE, 8(12):e83846.
PMID: 24376766 -
Species: Human
Sample Types: Whole Cells
Applications: BlockingJelicic K et al. (2013), The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-beta1 production and FcRL4 expression. Nat Immunol, 14(12):1256-65.
PMID: 24162774 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotOida T et al. (2012), Overexpression of TGF-ß 1 gene induces cell surface localized glucose-regulated protein 78-associated latency-associated peptide/TGF-ß. J. Immunol., 185(6):3529-35.
PMID: 20720212 -
Species: Mouse
Sample Types: Saliva
Applications: Western BlotVitsky A et al. (2009), Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues. Am. J. Pathol., 174(6):2137-49.
PMID: 19406991 -
Species: Mouse
Sample Types: Whole Cells
Applications: NeutralizationPalma C et al. (2008), The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response. Vaccine, 26(33):4237-43.
PMID: 18584925 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-PYu S et al. (2008), TGF-beta promotes thyroid epithelial cell hyperplasia and fibrosis in IFN-gamma-deficient NOD.H-2h4 mice. J. Immunol., 181(3):2238-45.
PMID: 18641364 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryTabata T et al. (2008), Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production. Am. J. Pathol., 172(4):1127-40.
PMID: 18349127 -
Species: Mouse
Sample Types: Whole Cells
Applications: Flow CytometryRuzek MC et al. (2007), Characterization of in vitro antimurine thymocyte globulin-induced regulatory T cells that inhibit graft-versus-host disease in vivo. Blood, 111(3):1726-34.
PMID: 18025149 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCMurphy MO et al. (2006), Expression of growth factors and growth factor receptor in non-healing and healing ischaemic ulceration. Eur J Vasc Endovasc Surg, 31(5):516-22.
PMID: 16427789 -
Species: Human
Sample Types: Whole Cells
Applications: NeutralizationNeurohr C et al. (2006), Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am. J. Respir. Cell Mol. Biol., 35(2):252-9.
PMID: 16574941 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotLin J et al. (2006), The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia. Mol. Cell. Biol., 26(12):4577-85.
PMID: 16738323 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-FrDasgupta S et al. (2006), Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells. J. Cell. Biochem., 97(5):1036-51.
PMID: 16294321 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: NeutralizationGodfrey WR et al. (2005), Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. Blood, 105(2):750-8.
PMID: 15374887 -
Species: Mouse
Sample Types: In Vivo
Applications: NeutralizationMesples B et al. (2005), Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice. Neurobiol. Dis., 18(1):193-205.
PMID: 15649710 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCHelantera I et al. (2005), Persistent cytomegalovirus infection is associated with increased expression of TGF-beta1, PDGF-AA and ICAM-1 and arterial intimal thickening in kidney allografts. Nephrol. Dial. Transplant., 20(4):790-6.
PMID: 15716293 -
Species: Guinea Pig
Sample Types: In Vivo
Applications: NeutralizationAllen SS et al. (2004), Effect of neutralizing transforming growth factor beta1 on the immune response against Mycobacterium tuberculosis in guinea pigs. Infect. Immun., 72(3):1358-63.
PMID: 14977939 -
Species: Rat
Sample Types: Whole Cells
Applications: NeutralizationConant SB et al. (2004), Autoreactive T cells persist in rats protected against experimental autoimmune encephalomyelitis and can be activated through stimulation of innate immunity. J. Immunol., 172(9):5322-8.
PMID: 15100271 -
Species: Rabbit
Sample Types: Whole Tissue
Applications: IHC-FrOhtani K et al. (2004), Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits. Gene Ther., 11(2):126-32.
PMID: 14712296
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Customer Reviews for TGF-beta 1/1.2 Antibody (1)
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Application: B/NSample Tested: MRC-5 human embryonic lung fibroblast cell lineSpecies: HumanVerified Customer | Posted 06/28/2017
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FAQs for TGF-beta 1/1.2 Antibody
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Does AF-101-NA detect other isoforms of TGF-beta?
Cross-reactivity testing results are listed in the Specificity section on the Product Datasheet: less than 15% cross-reactivity with recombinant amphibian TGF-beta 5 and less than 2% with TGF-beta 2 and TGF-beta 3, have been observed, as measured by direct ELISA.