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SARS-CoV-1/2 Spike RBD Llamabody Antibody

Recombinant Monoclonal Antibody.
SARS-CoV-2 Spike RBD Binding to ACE-2-transfected HEK293 Human Cell Line is Blocked by SARS-Cov-1/2 Spike RBD Llamabody.
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Key Product Details

Species Reactivity: SARS-CoV-1/2
Immunogen: Recombinant Llama VHH sequence based on VHH72 in Wrapp, D. et al. (2020) Cell 181: 1004. Bivalent Llama VHH-Human IgG1 Fusion Antibody.
Accession # YP_009724390
Applications: Block/Neutralize, ELISA
Label: Unconjugated
Source: Recombinant Monoclonal Human IgG1 Clone # VHH72
Specificity: Detects Recombinant SARS-CoV-2 Spike Protein S1 Receptor Binding Domain (RBD) in direct ELISA. In direct ELISA, no cross-reactivity with SARS-CoV-2 Spike Protein S2 is observed. VHH72 binding to SARS-CoV-1 RBD and SARS-CoV-2 has been reported in Wrapp, D. et al. (2020) Cell 181: 1004.

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  • What is the Isoelectricpoint (pI) of SARS-CoV-1/2 Spike RBD Llamabody VHH MAb (Clone VHH72), Catalog # LMAB10541?

    The pI of SARS-CoV-1/2 Spike RBD Llamabody VHH MAb (Cl VHH72), Catalog # LMAB10541, is 6.35 for the primary species. It is not unexpected to observe a range of pI from 6.1 to 6.9 due to some variability in glycosylation.

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