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Spike RBD Products

The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.

202 results for "Spike RBD" in Products

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Spike RBD Products

The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.

202 results for "Spike RBD" in Products

Catalog #: FAB10827R
Flow
Catalog #: NBP3-21466
ELISA
ELISA, Block

Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs

ELISA, Block

Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs

ELISA, Block

Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs

BA

Delta Variant (India) L452R T478K

Mammalian CHO Cell Expressed, High ACE-2 Binding

HEK293 Expressed, High ACE-2 Binding

HEK293 Expressed, High ACE-2 Binding

IHC, Block

Recombinant Monoclonal Antibody. His-tagged VHH domain.

WB, Simple Western
Block, ICC

Beta Variant (South Africa), K417N, E484K, N501Y

BA

Biotinylated via Amines

BA
ELISA, Block
WB, Flow, ICC
BA

His-tag

BA

A.23.1 Variant

Block, ICC, Neut
BA
BA

His-tag

WB, Flow

Recombinant Monoclonal Antibody.

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