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Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
144 results for "Spike RBD" in Products
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Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
144 results for "Spike RBD" in Products
BA
HEK293 Expressed, High ACE-2 Binding
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
MAB105801
Block
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #1035419 |
| Applications : | Block/Neutralize |
BA
CHO Expressed. Trimerization Domain
| Source : | CHO |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
MAB11023
ICC
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2841A |
| Applications : | Immunocytochemistry/Immunofluorescence |
Catalog #:
MAB10904
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1045316 |
| Applications : | Western Blot |
Catalog #:
AFG10500
BA
His-tag
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
10876-CV
BA
Delta Variant (India) L452R T478K
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
WB
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1034522 |
| Applications : | Western Blot |
Catalog #:
MAB105808
ELISA, Block
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1035753 |
| Applications : | Block/Neutralize, ELISA |
Catalog #:
MAB108271
Block, ICC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1042445 |
| Applications : | Block/Neutralize, Immunocytochemistry/Immunofluorescence |
Catalog #:
10812-CV
BA
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
AFG11094
BA
Omicron Variant His-tag
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
10908-CV
BA
Delta Plus
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
MAB105406
ELISA, Block
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #1035240 |
| Applications : | Block/Neutralize, ELISA |
Catalog #:
MAB105401
WB, Simple Western
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1034515 |
| Applications : | Simple Western, Western Blot |
Catalog #:
MAB11024
ICC
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #1049541 |
| Applications : | Immunocytochemistry/Immunofluorescence |
Catalog #:
11094-CV
BA
Omicron Variant
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
ELISA
RUO Quantitative ELISA. Patent Pending.
| Sensitivity : | 3.2 AU/mL |
| Assay Range : | 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Catalog #:
10735-CV
BA
Beta Variant (South Africa), K417N, E484K, N501Y
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
10905-CV
BA
Delta Plus
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Catalog #:
LMAB12503
Block
Recombinant Monoclonal Antibody. His-tagged VHH domain.
| Clonality : | Monoclonal |
| Host : | Llama Clone #L009.2.69N |
| Applications : | Block/Neutralize |
Catalog #:
MAB105807
ELISA, Block
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #1035740 |
| Applications : | Block/Neutralize, ELISA |
Catalog #:
DSR200-CE
ELISA
Available in the EU and UK only. For research testing.
| Sensitivity : | 3.2 AU/mL |
| Assay Range : | 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma) |
| Applications : | ELISA |
Catalog #:
BT10500
BA
Biotinylated via Amines
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
