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Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
175 results for "Spike RBD" in Products
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Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
175 results for "Spike RBD" in Products
His-tag
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2841A |
| Applications : | Immunocytochemistry/Immunofluorescence |
Delta Variant (India) L452R T478K
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
HEK293 Expressed, High ACE-2 Binding
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Kappa Variant L452R E484Q
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Tn5 Insect Cell Expressed, High ACE-2 Binding
| Source : | T. ni (baculovirus) |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
His-tag
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Recombinant Monoclonal Antibody. His-tagged VHH domain.
| Clonality : | Monoclonal |
| Host : | Llama Clone #L009.1.32N |
| Applications : | Block/Neutralize, Immunohistochemistry |
Mammalian CHO Cell Expressed, High ACE-2 Binding
| Source : | CHO |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
N439K, E484K
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1045316 |
| Applications : | Western Blot |
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | QHR63300.2 |
| Applications : | Bioactivity |
| Source : | HEK293 |
| Accession # : | YP_003767.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #1045017 |
| Applications : | Immunocytochemistry/Immunofluorescence, Simple Western, Western Blot |
Biotinylated via Amines
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Sf21 Expressed, High ACE-2 Binding
| Source : | Sf 21 (baculovirus) |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Mammalian CHO Cell Expressed
| Source : | CHO |
| Accession # : | NP_828851.1 |
| Applications : | Bioactivity |
N501Y Mutation found in Alpha, Beta, and Gamma Variants
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
CHO Expressed, High ACE-2 Binding
| Source : | CHO |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | QHR63300.2 |
| Applications : | Bioactivity |
Delta Variant (India)
| Source : | HEK293 |
| Accession # : | YP_009724390.1 |
| Applications : | Bioactivity |
Recombinant Monoclonal Antibody.
| Clonality : | Monoclonal |
| Host : | Rabbit IgG Clone #2820D |
| Applications : | Block/Neutralize, Immunocytochemistry/Immunofluorescence |
