
Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
144 results for "Spike RBD" in Products
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Spike RBD Products
The coronavirus Spike protein receptor binding domain (RBD) resides within the S1 subunit and is responsible for binding to host cell receptors and initiating viral infection. Past coronaviruses SARS and MERS along with the global pandemic caused by SARS-CoV-2 have sparked great interest and scientific discovery leading to new vaccines and drug development. At the heart of coronavirus biology lies the Spike protein and its receptor binding domain. The Spike RBD is a 26 kDa domain consisting of a twisted five-stranded antiparallel beta sheet and sits at the apex of each Spike protein monomer. The Spike RBD is flexible thanks to a hinge region that allows for conformational changes that expose (up or open conformation) or hide (down or closed conformation) its receptor contacts. For SARS-CoV-2, the Spike RBD recognizes and tightly binds to the human receptor ACE-2. In the closely related MERS coronavirus, human DPPIV/CD26 acts as the receptor.
144 results for "Spike RBD" in Products
HEK293 Expressed, High ACE-2 Binding
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035419 |
Applications : | Block/Neutralize |
CHO Expressed. Trimerization Domain
Source : | CHO |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #2841A |
Applications : | Immunocytochemistry/Immunofluorescence |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #1045316 |
Applications : | Western Blot |
His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Delta Variant (India) L452R T478K
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #1034522 |
Applications : | Western Blot |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1035753 |
Applications : | Block/Neutralize, ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1042445 |
Applications : | Block/Neutralize, Immunocytochemistry/Immunofluorescence |
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Omicron Variant His-tag
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Delta Plus
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035240 |
Applications : | Block/Neutralize, ELISA |
Clonality : | Monoclonal |
Host : | Mouse IgG2b Clone #1034515 |
Applications : | Simple Western, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #1049541 |
Applications : | Immunocytochemistry/Immunofluorescence |
Omicron Variant
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
RUO Quantitative ELISA. Patent Pending.
Sensitivity : | 3.2 AU/mL |
Assay Range : | 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Beta Variant (South Africa), K417N, E484K, N501Y
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Delta Plus
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |
Recombinant Monoclonal Antibody. His-tagged VHH domain.
Clonality : | Monoclonal |
Host : | Llama Clone #L009.2.69N |
Applications : | Block/Neutralize |
Detects SARS-CoV-2 Spike RBD and Spike S1 in sandwich ELISAs
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #1035740 |
Applications : | Block/Neutralize, ELISA |
Available in the EU and UK only. For research testing.
Sensitivity : | 3.2 AU/mL |
Assay Range : | 3.2 - 160 AU/mL (Serum, EDTA Plasma, Heparin Plasma) |
Applications : | ELISA |
Biotinylated via Amines
Source : | HEK293 |
Accession # : | YP_009724390.1 |
Applications : | Bioactivity |