Klotho beta Antibody [DyLight 350]
Novus Biologicals, part of Bio-Techne | Catalog # AF2619D
Conjugate
Catalog #
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
DyLight 350 (Excitation = 353 nm, Emission = 432 nm)
Antibody Source
Polyclonal Goat IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Klotho beta (R&D Systems, Catalog # 2619-KB)
Phe53-Leu995
Accession # NP_112457
Phe53-Leu995
Accession # NP_112457
Specificity
Detects mouse Klotho beta in direct ELISAs and Western blots. In these formats, approximately 5% cross‑reactivity with recombinant mouse Klotho is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Klotho beta Antibody [DyLight 350]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Klotho beta
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
Alternate Names
KLB
Gene Symbol
KLB
Additional Klotho beta Products
Product Documents for Klotho beta Antibody [DyLight 350]
Product Specific Notices for Klotho beta Antibody [DyLight 350]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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