
Klotho beta Products
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
17 results for "Klotho beta" in Products
Application
Conjugates
Clonality
Host Species
Isotype
Clone
Low Endotoxin
Sample Size
Citations
Reviews
Klotho beta Products
Klotho beta is expressed primarily in the liver and pancreas and functions as a cofactor for FGF-19 subfamily member interactions with their receptors. It facilitates human FGF-19 (mouse FGF-15) binding to FGF R4 in the liver to inhibit bile acid synthesis. It also enhances FGF-21 binding to FGF R1c in adipocytes, leading to increased Insulin-dependent glucose uptake.
17 results for "Klotho beta" in Products
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #885935 |
Applications : | Simple Western, Western Blot |
Source : | NS0 |
Accession # : | Q86Z14 |
Applications : | Bioactivity |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Assay Range : | 31.2 - 2,000 pg/mL |
Applications : | ELISA |
Source : | NS0 |
Accession # : | EHH53620.1 |
Applications : | Bioactivity |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Source : | NS0 |
Accession # : | NP_112457 |
Applications : | Bioactivity |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunocytochemistry/Immunofluorescence, Western Blot |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |
Recombinant Monoclonal Antibody.
Clonality : | Monoclonal |
Host : | Rabbit IgG Clone #1025C |
Applications : | Flow Cytometry |