Human SOX17 Antibody Best Seller

Name: Human SOX17 Antibody
Brand: R&D Systems
SKU: AF1924
Rating: 5 (16 reviews)

Catalog # AF1924 | R&D Systems, Inc. a Bio-Techne Brand

(16)

Citations (289)

Product Datasheet / COA / SDS

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Product Summary
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Chromatin Immunoprecipitation (ChIP), Immunocytochemistry, Simple Western, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Product Summary for Human SOX17 Antibody

Immunogen

E. coli-derived recombinant human SOX17
Asp177-Val414
Accession # Q9H6I2

Specificity

Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX18 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human SOX17 Antibody

Detection of Human SOX17 by Western Blot.

Western blot shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+). PVDF membrane was probed with 1 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). A specific band was detected for SOX17 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Detection of SOX17-regulated Genes by Chromatin Immunoprecipitation.

Endoderm-differentiated D3 mouse embryonic stem cell line was fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX17/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) or control antibody (AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (MAG999) and DNA was purified using chelating resin solution. Thep21promoter was detected by standard PCR.

SOX17 in B16 Mouse Cell Line.

SOX17 was detected in immersion fixed B16 mouse melanoma cell line using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counter-stained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

SOX17 in Human BG01V Cells.

SOX17 was detected in immersion fixed endoderm differentiated BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel; NL001) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Detection of Human SOX17 by Simple Western^TM.

Simple Western lane view shows lysates of BG01V human embryonic stem cells untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 59 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Detection of Human SOX17 by Simple Western^TM.

Simple Western lane view shows lysates of iBJ6 human induced pluripotent stem cell line untreated (-) or endoderm differentiated (+), loaded at 0.2 mg/mL. A specific band was detected for SOX17 at approximately 58 kDa (as indicated) using 10 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Detection of Human SOX17 by Western Blot.

Western blot shows lysates of SK‑OV‑3 human ovarian adenocarcinoma cell line, OVCAR‑3 human ovarian carcinoma cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human SOX17 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1924) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for SOX17 at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1.

View 4 more images

Applications for Human SOX17 Antibody

Application

Recommended Usage

Chromatin Immunoprecipitation (ChIP)

5 µg/5 x 10⁶ cells
Sample: Endoderm-differentiated D3 mouse embryonic stem cell line chromatin, p21 promoter detected by standard PCR.

Immunocytochemistry

5-15 µg/mL
Sample: Immersion fixed B16 mouse melanoma cell line and immersion fixed endoderm differentiated BG01V human embryonic stem cells

Simple Western

10 µg/mL
Sample: Endoderm differentiated BG01V human embryonic stem cells and endoderm differentiated iBJ6 human induced pluripotent stem cell line

Western Blot

1-2 µg/mL
Sample: Endoderm differentiated BG01V human embryonic stem cells, SK‑OV‑3 human ovarian adenocarcinoma cell line and OVCAR‑3 human ovarian carcinoma cell line

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 16 reviews rated 4.8 using AF1924 in the following applications:

Immunocytochemistry/Immunofluorescence (8 Reviews)
Immunofluorescence (3 Reviews)
Immunohistochemistry (2 Reviews)
It works very well. (1 Review)
Western Blot (1 Review)
single cells from a ESC to endoderm i... (1 Review)

Formulation, Preparation and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX17

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).

References

Kanai-Azuma, M. et al. (2002) Development 129:2367.
Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.

Long Name

Transcription Factor SOX17

Alternate Names

SOX17, FLJ22252, SRY (sex determining region Y)-box 17, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17, VUR3

Entrez Gene IDs

64321 (Human)

Gene Symbol

SOX17

UniProt

Q9H6I2

Product Documents for Human SOX17 Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human SOX17 Antibody

For research use only

Citations
Reviews

Citations for Human SOX17 Antibody (289)

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Citations are publications that use Bio-Techne products. Selected citations for Human SOX17 Antibody include:

Species: Human
Sample Types: Whole Cells
Applications: ICC

Li et al. (2023-05-24), Transcriptome-based chemical screens identify CDK8 as a common barrier in multiple cell reprogramming systems Cell reports
PMID: 37235474
Species: Human
Sample Types: Transduced Whole Cells
Applications: ICC

W Zeng et al. (2023-04-17), Generation of two induced pluripotent stem cell lines from spinal muscular atrophy type 1 patients carrying no functional copies of SMN1 gene Stem Cell Research, 2023-069(0):103095.
PMID: 37087898
Species: Human
Sample Types: Whole Cells
Applications: ICC

T Ukaji et al. (2023-04-17), Generation and characterization of a human iPSC line (JUFMDOi007-A) from a patient with Usher syndrome due to mutation in USH2A Stem Cell Research, 2023-069(0):103100.
PMID: 37099934
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC

S Merkert et al. (2023-04-01), Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing Stem Cell Research, 2023-069(0):103090.
PMID: 37104932
Species: Human
Sample Types: Transduced Whole Cells
Applications: Flow Cytometry

Y Gao et al. (2023-03-28), Efficient generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells Stem Cell Research, 2023-069(0):103088.
PMID: 37099933
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

AA Almad et al. (2023-03-26), Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A Stem Cell Research, 2023-069(0):103083.
PMID: 37003180
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

AH Kim et al. (2023-03-08), Establishment of TUBB3-mCherry knock-in human pluripotent stem cell line using CRISPR/Cas9 (SNUe003-A-4) Stem Cell Research, 2023-069(0):103064.
PMID: 36913849
Species: Human
Sample Types: Whole Cells
Applications: ICC

P Madrigal et al. (2023-01-25), Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation Nature Communications, 2023-014(1):405.
PMID: 36697417
Species: Human
Sample Types: Whole Tissue
Applications: IHC

MAS Fonseca et al. (2023-01-09), Single-cell transcriptomic analysis of endometriosis Nature Genetics, 2023-00(0).
PMID: 36624343
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

KM Yammine et al. (2023-01-06), Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis Stem Cell Research, 2023-067(0):103020.
PMID: 36682125
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

A Uchida et al. (2022-12-21), SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse Nature Communications, 2022-113(1):7860.
PMID: 36543770
Species: Human
Sample Types: Whole Cells
Applications: ICC

L Li et al. (2022-12-09), Generation of a human iPSC line (CIBi014-A) from a patient with Parkinson's disease carrying a novel heterozygotic PARK8 (LRRK2) mutation Stem Cell Research, 2022-166(0):102995.
PMID: 36528012
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Horschitz et al. (2022-12-05), Generation of three induced pluripotent stem cell lines carrying different variants of the BDNF (Val66Met) polymorphism Stem Cell Research, 2022-166(0):102989.
PMID: 36473250
Species: Human
Sample Types: Whole Cells
Applications: ICC

L Yang et al. (2022-12-05), Generation of an induced pluripotent stem cell line (IPCASi001-A) from an autism spectrum disorder individual without intellectual disability Stem Cell Research, 2022-166(0):102994.
PMID: 36502620
Species: Human
Sample Types: Embryo
Applications: IHC/IF

D Shang et al. (2022-12-01), PGCLCs of human 45,XO reveal pathogenetic pathways of neurocognitive and psychosocial disorders Cell & bioscience, 2022-112(1):194.
PMID: 36457060
Species: Human
Sample Types: Whole Tissue
Applications: IHC

K Ruangrung et al. (2022-11-19), Analysis of Influenza A virus infection in human induced pluripotent stem cells (hiPSCs) and their derivatives Virus research, 2022-1323(0):199009.
PMID: 36414188
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

DC Miller et al. (2022-11-17), Generation of induced pluripotent stem cells from three individuals with Huntington's disease Stem Cell Research, 2022-165(0):102976.
PMID: 36434993
Species: Mouse
Sample Types: Embryos
Applications: IHC

K Krawczyk et al. (2022-11-16), Paracrine interactions through FGFR1 and FGFR2 receptors regulate the development of preimplantation mouse chimaeric embryo Oncogene, 2022-112(11):220193.
PMID: 36382369
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

JH Song et al. (2022-10-17), Developmental Potency and Metabolic Traits of Extended Pluripotency Are Faithfully Transferred to Somatic Cells via Cell Fusion-Induced Reprogramming Cells, 2022-111(20).
PMID: 36291134
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

H Tomita et al. (2022-09-16), 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome Elife, 2022-011(0).
PMID: 36111785
Species: Human
Sample Types: Organoid
Applications: IHC

T Steiner et al. (2022-09-15), RNA-based generation of iPSCs from a boy carrying the mutation m.9185ï¿½T>C in the mitochondrial gene MT-ATP6 and from his healthy mother Stem Cell Research, 2022-064(0):102920.
PMID: 36137325
Species: Human
Sample Types: Whole Cells
Applications: IHC

MC Jaboreck et al. (2022-09-14), Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line Stem Cell Research, 2022-064(0):102918.
PMID: 36162332
Species: Human
Sample Types: Whole Cells
Applications: ICC

TXA Pham et al. (2022-09-01), Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells Cell Stem Cell, 2022-029(9):1346-1365.e10.
PMID: 36055191
Species: Human
Sample Types: Cell Lysates,Whole Cells
Applications: Western Blot,IF

S Mukherjee et al. (2022-08-23), SOX transcription factors direct TCF-independent WNT/beta-catenin responsive transcription to govern cell fate in human pluripotent stem cells Cell Reports, 2022-040(8):111247.
PMID: 36001974
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

J Contreras et al. (2022-08-10), Generation of an induced pluripotent stem cell line NCHi003-A from a 11-year-old male with pulmonary atresia with intact ventricular septum (PA-IVS) Stem Cell Research, 2022-064(0):102893.
PMID: 35987120
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

M Alonzo et al. (2022-08-09), Characterization of an iPSC line NCHi006-A from a patient with hypoplastic left heart syndrome (HLHS) Stem Cell Research, 2022-064(0):102892.
PMID: 35987121
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

Z Jiang et al. (2022-08-04), Production of a human iPSC line from an early-onset Parkinson's disease patient with a novel CHCHD2 gene truncated mutation Stem Cell Research, 2022-064(0):102881.
PMID: 35944313
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

H Okumura et al. (2022-08-03), Establishment of induced pluripotent stem cells from a patient with 16p13.11 duplication and VPS13B deletion Stem Cell Research, 2022-064(0):102884.
PMID: 35944312
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

J Liu et al. (2022-07-30), Generation of a human induced pluripotent stem cell line carrying the TYR c.575C>A (p.Ser192Tyr) and c.1205G>A (p.Arg402Gln) variants in homozygous state using CRISPR-Cas9 genome editing Stem Cell Research, 2022-064(0):102880.
PMID: 35933957
Species: Mouse
Sample Types: Whole Cells
Applications: IHC

JJ Thompson et al. (2022-07-23), Extensive co-binding and rapid redistribution of NANOG and GATA6 during emergence of divergent lineages Nature Communications, 2022-013(1):4257.
PMID: 35871075
Species: Human
Sample Types: Whole Cells
Applications: ICC

EZ Sim et al. (2022-07-19), Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization Cell Reports, 2022-040(3):111120.
PMID: 35858556
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow Cytometry

Y Sun et al. (2022-07-11), Generation of a RRAGA knockout human iPSC line GIBHi002-A-5 using CRISPR/Cas9 technology Oncogene, 2022-063(0):102859.
PMID: 35870248
Species: Human
Sample Types: Cell Lysates,Whole Cells
Applications: ICC,Western Blot

WS Fagg et al. (2022-05-20), Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate Nucleic Acids Research, 2022-050(9):5313-5334.
PMID: 35544276
Species: Human
Sample Types: Whole Cells
Applications: ICC

Y Shi et al. (2022-05-04), Generation of a human iPSC line CIBi011-A from amniocytes of a healthy fetus Stem Cell Research, 2022-062(0):102801.
PMID: 35609349
Species: Human
Sample Types: Organoids
Applications: IHC

F Papes et al. (2022-05-02), Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content Nature Communications, 2022-013(1):2387.
PMID: 35501322
Species: Human
Sample Types: Spheroid
Applications: ICC

X Hu et al. (2022-04-04), Generation of a human induced pluripotent stem cell line FMUPDCi001-A from a patient with mental retardation, autosomal recessive 36 (MRT36) carrying the variants c.219dupA and c.587Cï¿½>ï¿½T in ADAT3 Stem Cell Research, 2022-061(0):102777.
PMID: 35405382
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC

HM Lee et al. (2022-04-04), Generation of alphaMHC-EGFP knock-in in human pluripotent stem cell line, SNUe003-A-3 using CRISPR/Cas9-based gene targeting Stem Cell Research, 2022-061(0):102779.
PMID: 35427904
Species: Human
Sample Types: Whole Cells
Applications: ICC

A Manhas et al. (2022-03-31), Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants Stem Cell Research, 2022-061(0):102774.
PMID: 35413566
Species: Human
Sample Types: Transduced Whole Cells
Applications: ICC

J Jeong et al. (2022-03-23), Elimination of Reprogramming Transgenes Facilitates the Differentiation of Induced Pluripotent Stem Cells into Hepatocyte-like Cells and Hepatic Organoids Biology, 2022-011(4).
PMID: 35453693
Species: Human
Sample Types: Whole Cells
Applications: ICC

M Breyer et al. (2022-03-14), Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376Aï¿½>ï¿½G of unknown pathogenicity in Fabry disease Stem Cell Research, 2022-061(0):102747.
PMID: 35325818
Species: Human
Sample Types: Whole Cells
Applications: ICC

C Lorenz et al. (2022-03-08), Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993Tï¿½>ï¿½G or m.8993Tï¿½>ï¿½C in the mitochondrial gene MT-ATP6 Stem Cell Research, 2022-061(0):102742.
PMID: 35279592
Species: Human
Sample Types: Whole Cells
Applications: ICC

W Chiu et al. (2022-02-26), Generation of a MSX1 knockout human embryonic stem cell line using CRISPR/Cas9 technology Stem Cell Research, 2022-060(0):102729.
PMID: 35247841
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

C Royer et al. (2022-02-17), ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis Nature Communications, 2022-013(1):941.
PMID: 35177595
Species: Human
Sample Types: Whole Cells
Applications: ICC

D Han et al. (2022-02-16), A balanced Oct4 interactome is crucial for maintaining pluripotency Science Advances, 2022-08(7):eabe4375.
PMID: 35171666
Species: Mouse
Sample Types: Embryos
Applications: IHC

T Pock et al. (2022-02-10), GM-CSF perturbs cell identity in mouse pre-implantation embryos PLoS ONE, 2022-017(2):e0263793.
PMID: 35143564
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Chumchuen et al. (2022-01-19), Establishment of human induced pluripotent stem cell line MUi028-A from normal fetal skin fibroblasts Stem Cell Research, 2022-060(0):102675.
PMID: 35114587
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

OH Lee et al. (2021-12-27), Generation of a B2M homozygous knockout human somatic cell nuclear transfer-derived embryonic stem cell line using the CRISPR/Cas9 system Stem Cell Research, 2021-159(0):102643.
PMID: 34971932
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

C Lee et al. (2021-12-21), Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant Stem Cell Research, 2021-159(0):102638.
PMID: 34954454
Species: Mouse
Sample Types: Embryo
Applications: IHC

L Taher et al. (2021-12-09), The proteome, not the transcriptome, predicts that oocyte superovulation affects embryonic phenotypes in mice Scientific Reports, 2021-111(1):23731.
PMID: 34887460
Species: Human
Sample Types: Cell Lysates,Whole Cells
Applications: Western Blot,ICC,Flow Cytometry

Y Lan et al. (2021-12-07), Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation Cell Reports, 2021-137(10):110095.
PMID: 34879277
Species: Human
Sample Types: Whole Cells
Applications: ICC

M Liu et al. (2021-11-24), Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual Stem Cell Research, 2021-157(0):102607.
PMID: 34844101
Species: Human
Sample Types: Embryoid Bodies
Applications: IHC

S Jalil et al. (2021-11-24), Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts Stem Cell Reports, 2021-10(0).
PMID: 34822772
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

N Belbachir et al. (2021-11-23), Generation of two induced pluripotent stem cell lines from Brugada syndrome affected patients carrying SCN5A mutations Stem Cell Research, 2021-157(0):102605.
PMID: 34856468
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

S Heino et al. (2021-11-17), Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas Science Advances, 2021-17(47):eabj0512.
PMID: 34788095
Species: Human
Sample Types: Whole Cells
Applications: IHC

RJ Geusz et al. (2021-11-17), Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors Nature Communications, 2021-112(1):6636.
PMID: 34789735
Species: Human
Sample Types: Organoids
Applications: IHC

L Drakhlis et al. (2021-11-10), Generation of heart-forming organoids from human pluripotent stem cells Nature Protocols, 2021-10(0).
PMID: 34759383
Species: Human
Sample Types: Whole Cells
Applications: ICC

AF de Souza et al. (2021-11-10), Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients Cells, 2021-110(11).
PMID: 34831322
Species: Human
Sample Types: Whole Cells
Applications: ICC

C Völkner et al. (2021-11-10), Patient-Specific iPSC-Derived Neural Differentiated and Hepatocyte-like Cells, Carrying the Compound Heterozygous Mutation p.V1023Sfs*15/p.G992R, Present the "Variant" Biochemical Phenotype of Niemann-Pick Type C1 Disease International Journal of Molecular Sciences, 2021-122(22).
PMID: 34830064
Species: Human
Sample Types: Whole Cells
Applications: IF

JR Valcourt et al. (2021-11-09), Modulating mesendoderm competence during human germ layer differentiation Cell Reports, 2021-137(6):109990.
PMID: 34758327
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

E Sintov et al. (2021-11-02), A human ESC line for efficient CRISPR editing of pluripotent stem cells Stem Cell Research, 2021-157(0):102591.
PMID: 34741877
Species: Mouse
Sample Types: Embryo
Applications: IHC

K Krawczyk et al. (2021-11-02), Developmental capacity is unevenly distributed among single blastomeres of 2-cell and 4-cell stage mouse embryos Scientific Reports, 2021-111(1):21422.
PMID: 34728646
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Ding et al. (2021-10-22), CHD8 safeguards early neuroectoderm differentiation in human ESCs and protects from apoptosis during neurogenesis Cell Death & Disease, 2021-112(11):981.
PMID: 34686651
Species: Human
Sample Types: Whole Cells
Applications: ICC

HC Ting et al. (2021-10-16), Coactivation of GSK3beta and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons Cells, 2021-110(10).
PMID: 34685754
Species: Human
Sample Types: Whole Cells
Applications: ICC

L Scaramuzzi et al. (2021-09-15), Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing Cells, 2021-010(9).
PMID: 34572080
Species: Human
Sample Types: Whole Cells
Applications: IHC

T Bluhmki et al. (2021-08-23), Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96?Transwell air-liquid interface model Scientific Reports, 2021-011(1):17028.
PMID: 34426605
Species: Human
Sample Types: Whole Cells
Applications: IHC

Y Shamshirga et al. (2021-08-16), Rapid target validation in a Cas9-inducible hiPSC derived kidney model Scientific Reports, 2021-011(1):16532.
PMID: 34400685
Species: Human
Sample Types: Whole Cells
Applications: IHC

A Usman et al. (2021-08-05), Generation of pulmonary arterial hypertension patient-specific induced pluripotent stem cell lines from three unrelated patients with a heterozygous missense mutation in exon 12, a heterozygous in-frame deletion in exon 3 and a missense mutation in exon 11 of the BMPR2 gene Stem Cell Research, 2021-055(0):102488.
PMID: 34388490
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

B Li et al. (2021-07-30), Characterizing the Low-Dose Effects of Methylmercury on the Early Stages of Embryo Development Using Cultured Human Embryonic Stem Cells Environmental health perspectives, 2021-0129(7):77007.
PMID: 34328791
Species: Human
Sample Types: Whole Cells
Applications: ICC

BC Liu et al. (2021-07-12), Global Transcriptional Analyses of the Wnt-Induced Development of Neural Stem Cells from Human Pluripotent Stem Cells International Journal of Molecular Sciences, 2021-022(14).
PMID: 34299091
Species: Human
Sample Types: Whole Cells
Applications: ICC

L Ma et al. (2021-06-18), Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls Stem Cell Research, 2021-054(0):102435.
PMID: 34182254
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

PJ Houweling et al. (2021-06-17), Generating an iPSC line (with isogenic control) from the PBMCs of an ACTA1 (p.Gly148Asp) nemaline myopathy patient Stem Cell Research, 2021-054(0):102429.
PMID: 34157503
Species: Human
Sample Types: Whole Cells
Applications: ICC

DJ Truong et al. (2021-06-03), Non-invasive and high-throughput interrogation of exon-specific isoform expression Nature Cell Biology, 2021-023(6):652-663.
PMID: 34083785
Species: Mouse
Sample Types: Embryoid Bodies
Applications: IHC

PF Xu et al. (2021-06-02), Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre Nature Communications, 2021-012(1):3277.
PMID: 34078907
Species: Human
Sample Types: Embryo
Applications: IHC

D Meisterman et al. (2021-05-17), Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification Cell Stem Cell, 2021-00(0).
PMID: 34004179
Species: Human
Sample Types: Whole Cells
Applications: ICC

N Ge et al. (2021-05-12), Generation and characterization of three induced pluripotent stem cell lines (NUIGi047-A, NUIGi047-B, NUIGi047-C) from a 7-year-old healthy Caucasian male Stem Cell Research, 2021-053(0):102389.
PMID: 34088016
Species: Human
Sample Types: Embryo
Applications: ICC

A Yanagida et al. (2021-05-05), Naive stem cell blastocyst model captures human embryo lineage segregation Cell Stem Cell, 2021-028(6):1016-1022.e4.
PMID: 33957081
Species: Marmoset
Sample Types: Whole Cells
Applications: ICC

S Yoshimatsu et al. (2021-04-30), Establishing an induced pluripotent stem cell line from neonatal common marmoset fibroblasts by an all-in-one episomal vector approach Stem Cell Research, 2021-053(0):102380.
PMID: 34088009
Species: Canine
Sample Types: Whole Cells
Applications: ICC

S Yoshimatsu et al. (2021-04-29), Non-viral derivation of a transgene-free induced pluripotent stem cell line from a male beagle dog Stem Cell Research, 2021-053(0):102375.
PMID: 34088004
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

J Bayerl et al. (2021-04-28), Principles of signaling pathway modulation for enhancing human naive pluripotency induction Cell Stem Cell, 2021-00(0).
PMID: 33915080
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

D Gerace et al. (2021-04-27), Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny Stem Cell Research, 2021-053(0):102371.
PMID: 34088000
Species: Human
Sample Types: Whole Cells
Applications: ICC

DJ Sutcliffe et al. (2021-04-19), Induced pluripotent stem cells from subjects with Lesch-Nyhan disease Scientific Reports, 2021-011(1):8523.
PMID: 33875724
Species: Human
Sample Types: Whole Tissue
Applications: IHC

HQ Dinh et al. (2021-04-13), Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube Cell Reports, 2021-035(2):108978.
PMID: 33852846
Species: Human
Sample Types: Whole Cells
Applications: ICC

SJ Wu et al. (2021-04-12), Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression Nature Biotechnology, 2021-00(0).
PMID: 33846646
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

V Lucchino et al. (2021-04-09), Generation of human induced pluripotent stem cell lines (UNIMGi003-A and UNIMGi004-A) from two Italian siblings affected by Unverricht-Lundborg disease Stem Cell Research, 2021-053(0):102329.
PMID: 33865103
Species: Human
Sample Types: Whole Cells
Applications: ICC

G Guo et al. (2021-04-07), Human naive epiblast cells possess unrestricted lineage potential Cell Stem Cell, 2021-00(0).
PMID: 33831366
Species: Human
Sample Types: Whole Cells
Applications: ICC

L Ma et al. (2021-04-06), Generation of pathogenic TPP1 mutations in human stem cells as a model for neuronal ceroid lipofuscinosis type 2 disease Stem Cell Research, 2021-053(0):102323.
PMID: 33845243
Species: Human
Sample Types: Whole Cells
Applications: ICC

G Inak et al. (2021-03-26), Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome Nature Communications, 2021-012(1):1929.
PMID: 33771987
Species: Callithrix jacchus (Marmoset)
Sample Types: Whole Cells
Applications: ICC

S Yoshimatsu et al. (2021-03-24), Generation of a common marmoset embryonic stem cell line CMES40-OC harboring a POU5F1 (OCT4)-2A-mCerulean3 knock-in reporter allele Stem Cell Research, 2021-053(0):102308.
PMID: 33799281
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow Cytometry

JWS Jahng et al. (2021-03-12), Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene Stem Cell Research, 2021-053(0):102284.
PMID: 33743362
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

L Liu et al. (2021-03-11), Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy Stem Cell Research, 2021-053(0):102279.
PMID: 33743363
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

Y Yada et al. (2021-03-03), Human induced pluripotent stem cells generated from a patient with idiopathic basal ganglia calcification Stem Cell Research, 2021-053(0):102274.
PMID: 33714066
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

A Sahabian et al. (2021-02-12), Production and cryopreservation of definitive endoderm from human pluripotent stem cells under defined and scalable culture conditions Nature Protocols, 2021-00(0).
PMID: 33580232
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

L Drakhlis et al. (2021-02-08), Human heart-forming organoids recapitulate early heart and foregut development Nature Biotechnology, 2021-00(0).
PMID: 33558697
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

S Merkert et al. (2021-02-03), Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation in the MYH7 gene Stem Cell Research, 2021-052(0):102208.
PMID: 33578365
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow Cytometry

A Haase et al. (2021-01-30), Establishment of MHHi001-A-5, a GCaMP6f and RedStar dual reporter human iPSC line for in vitro and in vivo characterization and in situ tracing of iPSC derivatives Stem Cell Research, 2021-052(0):102206.
PMID: 33571874
Species: Transgenic Mouse,Human
Sample Types: Cell Lysates,Whole Cells,Whole Tissue
Applications: ICC,IHC,Western Blot

Y Fang et al. (2021-01-14), Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells Cell Stem Cell, 2021-00(0).
PMID: 33450185
Species: Human
Sample Types: Cell Lysates,Whole Cells
Applications: ICC,Western Blot

WS Fagg et al. (2021-01-01), Endoderm and Hepatic Progenitor Cells Engraft in the Quiescent Liver Concurrent with Intrinsically Activated Epithelial-to-Mesenchymal Transition Cell Transplantation, 2021-030(0):9636897219937.
PMID: 33657866
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

S Merkert et al. (2020-12-22), Generation of two human ISG15 knockout iPSC clones using CRISPR/Cas9 editing Stem Cell Research, 2020-150(0):102135.
PMID: 33383405
Species: Human
Sample Types: Whole Cells
Applications: ICC

Y Arioka et al. (2020-12-17), Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons EBioMedicine, 2020-163(0):103138.
PMID: 33341442
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

LHW Kung et al. (2020-12-10), Generation of a miR-26b stem-loop knockout human iPSC line, MCRIi019-A-1, using CRISPR/Cas9 editing Stem Cell Research, 2020-150(0):102118.
PMID: 33316599
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

M Kinoshita et al. (2020-12-02), Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency Cell Stem Cell, 2020-10(0).
PMID: 33271069
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Y Katagami et al. (2020-11-23), Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a Stem Cell Research, 2020-149(0):102095.
PMID: 33291009
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

S Scalise et al. (2020-11-07), Generation of iPSC lines from two patients affected by febrile seizure due to inherited missense mutation in SCN1A gene Stem Cell Research, 2020-149(0):102083.
PMID: 33370868
Species: Mouse
Sample Types: Whole Cells,Whole Tissue
Applications: ICC,IHC

R Fan et al. (2020-10-30), Wnt/Beta-catenin/Esrrb signalling controls the tissue-scale reorganization and maintenance of the pluripotent lineage during murine embryonic diapause Nat Commun, 2020-111(1):5499.
PMID: 33127892
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

FJ Hawkins et al. (2020-10-23), Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells Cell Stem Cell, 2020-10(0).
PMID: 33098807
Species: Human
Sample Types: Whole Cells
Applications: ICC

K Sekine et al. (2020-10-21), Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media Sci Rep, 2020-110(1):17937.
PMID: 33087763
Species: Human
Sample Types: Whole Cells
Applications: ICC

K Bono et al. (2020-10-08), Endosomal dysfunction in iPSC-derived neural cells from Parkinson's disease patients with VPS35 D620N Mol Brain, 2020-113(1):137.
PMID: 33032646
Species: Human
Sample Types: Whole Cells
Applications: ICC

SR Sripathy et al. (2020-09-17), Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome Stem Cell Res, 2020-048(0):102001.
PMID: 32971458
Species: Human
Sample Types: Whole Cells
Applications: ICC

A Sahabian et al. (2020-09-07), Generation of two hiPSC clones (MHHi019-A, MHHi019-B) from a primary ciliary dyskinesia patient carrying a homozygous deletion in the NME5 gene (c.415delA (p.Ile139Tyrfs*8)) Stem Cell Res, 2020-048(0):101988.
PMID: 32950024
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

LHW Kung et al. (2020-09-06), CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A Stem Cell Res, 2020-048(0):101962.
PMID: 33002832
Species: Human
Sample Types: Whole Cells,Organoid
Applications: ICC,Flow Cytometry,IHC

L Zhang et al. (2020-08-11), Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State Cell Stem Cell, 2020-00(0).
PMID: 32783886
Species: Human
Sample Types: Whole Cells
Applications: ICC

PA Barbuti et al. (2020-08-08), Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinsonï¿½s disease patient carrying the heterozygous p.A30P mutation in SNCA Stem Cell Res, 2020-048(0):101951.
PMID: 32798915
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Vallejo-Di et al. (2020-07-17), Generation of one iPSC line (IMEDEAi007-A) by Sendai Virus transduction of PBMCs from a Psoriasis donor Stem Cell Res, 2020-047(0):101917.
PMID: 32707489
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

LTP Khoa et al. (2020-06-30), Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation Cell Stem Cell, 2020-00(0).
PMID: 32610040
Species: Human
Sample Types: Whole Cells
Applications: ICC

PA Subramani et al. (2020-06-22), Plasmodium vivax liver stage assay platforms using Indian clinical isolates Malar. J., 2020-019(1):214.
PMID: 32571333
Species: Human
Sample Types: Whole Cells
Applications: ICC

J Serra-Vina et al. (2020-06-22), Generation and characterization of four Chediak-Higashi Syndrome (CHS) induced pluripotent stem cell (iPSC) lines Stem Cell Res, 2020-047(0):101883.
PMID: 32619719
Species: Human
Sample Types: Whole Cells
Applications: ICC

C Fan et al. (2020-06-01), TALEN-mediated biallelic inactivation of MYB in human embryonic stem cell lines WAe001-A-45 and WAe001-A-46 Stem Cell Res, 2020-046(0):101854.
PMID: 32526676
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

BJ Seo et al. (2020-05-30), Role of mitochondrial fission-related genes in mitochondrial morphology and energy metabolism in mouse embryonic stem cells Redox Biol, 2020-036(0):101599.
PMID: 32521505
Species: Human
Sample Types: Whole Cells
Applications: ICC

N Drick et al. (2020-05-20), Generation of two human induced pluripotent stem cell lines (MHHi017-A, MHHi017-B) from a patient with primary ciliary dyskinesia carrying a homozygous mutation (c.7915Cï¿½>ï¿½T [p.Arg2639*]) in the DNAH5 gene Stem Cell Res, 2020-046(0):101848.
PMID: 32470793
Species: Human
Sample Types: Whole Cells
Applications: ICC

Y Nakatake et al. (2020-05-19), Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors Cell Rep, 2020-031(7):107655.
PMID: 32433964
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Y Ueda et al. (2020-05-19), Intrauterine Pressures Adjusted by Reichert's Membrane Are Crucial for Early Mouse Morphogenesis Cell Rep, 2020-031(7):107637.
PMID: 32433954
Species: Human
Sample Types: Whole Cell
Applications: Flow Cytometry

J Dahlmann et al. (2020-05-18), Generation of two hiPSC lines (MHHi016-A, MHHi016-B) from a primary ciliary dyskinesia patient carrying a homozygous 5ï¿½bp duplication (c.248_252dup (p.Gly85Cysfs*11)) in exon 1 of the CCNO gene Stem Cell Res, 2020-046(0):101850.
PMID: 32464346
Species: Human
Sample Types: Whole Cell
Applications: ICC

V Meraviglia et al. (2020-05-05), Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation Stem Cell Res, 2020-046(0):101835.
PMID: 32485643
Species: Human
Sample Types: Whole Cell
Applications: ICC

K Kamata et al. (2020-04-29), Generation of a human induced pluripotent stem cell line, BRCi005-A, derived from a Best disease patient with BEST1 mutations Stem Cell Res, 2020-045(0):101782.
PMID: 32416576
Species: Human
Sample Types: Whole Cells
Applications: ICC,Functional Assay

M Tariq et al. (2020-04-24), Generation of three induced pluripotent stem cell lines from a Parkinson's disease patient with mutant PARKINï¿½(p. C253Y) Stem Cell Res, 2020-045(0):101822.
PMID: 32387897
Species: Human
Sample Types: Whole Cell
Applications: Flow Cytometry,ICC

H Suzuki et al. (2020-04-22), Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication Stem Cell Res, 2020-045(0):101828.
PMID: 32413791
Species: Human
Sample Types: Whole Cells
Applications: ICC

K Kamata et al. (2020-04-21), Generation of a human induced pluripotent stem cell line, BRCi004-A, derived from a patient with age-related macular degeneration Stem Cell Res, 2020-045(0):101787.
PMID: 32416577
Species: Human
Sample Types: Whole Cells
Applications: ICC

A Fleischer et al. (2020-04-18), iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation Mol Ther Methods Clin Dev, 2020-017(0):858-870.
PMID: 32373648
Species: Human
Sample Types: Whole Cells
Applications: ICC

V Meraviglia et al. (2020-04-08), Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene Stem Cell Res, 2020-045(0):101764.
PMID: 32315959
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Yoshida et al. (2020-04-06), Generation of intestinal organoids derived from human pluripotent stem cells for drug testing Sci Rep, 2020-010(1):5989.
PMID: 32249832
Species: Human,Mouse
Sample Types: Whole Tissue
Applications: IHC

M Uemura et al. (2020-04-03), Gallbladder wall abnormality in biliary atresia of mouse Sox17+/- neonates and human infants Dis Model Mech, 2020-013(4).
PMID: 31996362
Species: Human
Sample Types: Whole Cells
Applications: ICC

M Chen et al. (2020-03-29), Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation Stem Cell Res, 2020-045(0):101781.
PMID: 32305865
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Merkert et al. (2020-03-25), Generation of an induced pluripotent stem cell line (MHHi018-A) from a patient with Cystic Fibrosis carrying p.Asn1303Lys (N1303K) mutation Stem Cell Res, 2020-044(0):101744.
PMID: 32220772
Species: Human
Sample Types: Whole Cells
Applications: ICC

J Frew et al. (2020-03-16), Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency Mol Neurodegener, 2020-015(1):21.
PMID: 32178712
Species: Human
Sample Types: Whole Cells
Applications: ICC

E Slot et al. (2020-03-04), Generation of three iPSC lines from two patients with heterozygous FOXF1 mutations associated to Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins Stem Cell Res, 2020-044(0):101745.
PMID: 32169823
Species: Pan troglodytes (Chimpanzee)
Sample Types: Whole Cells
Applications: ICC

R Kitajima et al. (2020-02-28), Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells Stem Cell Res, 2020-044(0):101749.
PMID: 32151953
Species: Callithrix jacchus (Marmoset)
Sample Types: Whole Cells
Applications: ICC

S Yoshimatsu et al. (2020-02-21), Generation of a male common marmoset embryonic stem cell line DSY127-BV8VT1 carrying double reporters specific for the germ cell linage using the CRISPR-Cas9 and PiggyBac transposase systems Stem Cell Res, 2020-044(0):101740.
PMID: 32151954
Species: Human
Sample Types: Whole Cells
Applications: ICC

J Choi et al. (2020-01-20), Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells Redox Biol, 2020-030(0):101437.
PMID: 31981893
Species: Mouse
Sample Types: PSCs
Applications: IF

A Motazedian et al. (2020-01-06), Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids Nat. Cell Biol., 2020-022(1):60-73.
PMID: 31907413
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

DM Barry et al. (2019-12-13), Molecular determinants of nephron vascular specialization in the kidney Nat Commun, 2019-110(1):5705.
PMID: 31836710
Species: Human
Sample Types: Whole Cells
Applications: ICC

JR Alvarez-Do et al. (2019-12-12), Circadian Entrainment Triggers Maturation of Human Inï¿½Vitro Islets Cell Stem Cell, 2019-126(1):108-122.e10.
PMID: 31839570
Species: Mouse
Sample Types: Organoid
Applications: ICC

A Subramania et al. (2019-11-29), Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation Nat Commun, 2019-110(1):5462.
PMID: 31784515
Species: Human
Sample Types: Whole Cells
Applications: ICC

N Drick et al. (2019-11-19), Generation of a NKX2.1 - p63 double transgenic knock-in reporter cell line from human induced pluripotent stem cells (MHHi006-A-4) Stem Cell Res, 2019-142(0):101659.
PMID: 31791010
Species: Human
Sample Types: Whole Cells
Applications: ICC

M Chen et al. (2019-11-13), Generation of eight human induced pluripotent stem cell lines from Parkinson's disease patients carrying familial mutations Stem Cell Res, 2019-142(0):101657.
PMID: 31786474
Species: Human
Sample Types: Whole Cells
Applications: ICC

J Frew et al. (2019-11-08), Generation of an induced pluripotent stem cell line (UBCi001-A) from a presymptomatic individual carrying the R418X progranulin gene mutation Stem Cell Res, 2019-141(0):101582.
PMID: 31707213
Species: Human
Sample Types: Whole Cells
Applications: ICC

N Bredenkamp et al. (2019-11-07), Wnt Inhibition Facilitates RNA-Mediated Reprogramming of Human Somatic Cells to Naive Pluripotency Stem Cell Reports, 2019-113(6):1083-1098.
PMID: 31708477
Species: Human
Sample Types: Whole Cells
Applications: ICC

SY Lee et al. (2019-11-06), Generation of gene-corrected iPSC line, KIOMi002-A, from Parkinson's disease patient iPSC with LRRK2 G2019S mutation using BAC-based homologous recombination Stem Cell Res, 2019-141(0):101649.
PMID: 31731184
Species: Human
Sample Types: Whole Cells
Applications: ICC

C Lu et al. (2019-11-01), Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A) Stem Cell Res, 2019-141(0):101643.
PMID: 31707212
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

BJ Seo et al. (2019-10-31), Generation of Mouse Parthenogenetic Epiblast Stem Cells and Their Imprinting Patterns Int J Mol Sci, 2019-120(21).
PMID: 31683583
Species: Human
Sample Types: Whole Tissue
Applications: IHC

S Kinnear et al. (2019-10-29), Uterine SOX17: a key player in human endometrial receptivity and embryo implantation Sci Rep, 2019-19(1):15495.
PMID: 31664088
Species: Human
Sample Types: Whole Cells
Applications: ICC

L Xie et al. (2019-10-25), Generation of a homozygous HDAC6 knockout human embryonic stem cell line by CRISPR/Cas9 editing Stem Cell Res, 2019-141(0):101610.
PMID: 31775087
Species: Human
Sample Types: Whole Cells
Applications: ICC

AJ Duarte et al. (2019-10-18), Induced pluripotent stem cell line (INSAi001-A) from a Gaucher disease type 3 patient compound heterozygote for mutations in the GBA1 gene Stem Cell Res, 2019-141(0):101595.
PMID: 31678773
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Chhabra et al. (2019-10-15), Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids PLoS Biol., 2019-117(10):e3000498.
PMID: 31613879
Species: Human
Sample Types: Whole Cells
Applications: ICC

MM Abdul et al. (2019-10-15), Generation of an induced pluripotent stem cell line (GIBHi003-A) from a Parkinson's disease patient with mutant PINK1 (p. I368N) Stem Cell Res, 2019-141(0):101607.
PMID: 31778937
Species: Human
Sample Types: Whole Cells
Applications: ICC

Q Li et al. (2019-10-10), Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition PLoS ONE, 2019-114(10):e0223724.
PMID: 31600351
Species: Human
Sample Types: Whole Cells
Applications: ICC

V Lungova et al. (2019-09-24), Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure Nat Commun, 2019-010(1):4161.
PMID: 31551422
Species: Human
Sample Types: Whole Cells
Applications: ICC

F Tonon et al. (2019-09-19), In vitro metabolic zonation through oxygen gradient on a chip Sci Rep, 2019-09(1):13557.
PMID: 31537830
Species: Human
Sample Types: Whole Cells
Applications: ICC

MT De Angelis et al. (2019-09-19), Establishment and characterization of induced pluripotent stem cells (iPSCs) from central nervous system lupus erythematosus J. Cell. Mol. Med., 2019-00(0).
PMID: 31536674
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Yoshimatsu et al. (2019-08-27), A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology PLoS ONE, 2019-014(8):e0221164.
PMID: 31454364
Species: Human
Sample Types: Whole Cells,Cell Lysates
Applications: ICC,Western Blot

HJ Bai et al. (2019-08-12), SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes Stem Cells, 2019-00(0).
PMID: 31348575
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr

S Payne et al. (2019-07-22), Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart Nat Commun, 2019-010(1):3276.
PMID: 31332177
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

A Perea-Gome et al. (2019-07-15), Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse Sci Rep, 2019-09(1):10168.
PMID: 31308417
Species: Human
Sample Types: Whole Tissue
Applications: IHC

M Huang et al. (2019-06-13), Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis Cell Stem Cell, 2019-00(0).
PMID: 31204176
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Howden et al. (2019-05-04), The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line Stem Cell Res, 2019-038(0):101453.
PMID: 31082677
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Ross et al. (2019-04-25), Characterization of the first induced pluripotent stem cell line generated from a patient with autosomal dominant catecholaminergic polymorphic ventricular tachycardia due to a heterozygous mutation in cardiac calsequestrin-2 Stem Cell Res, 2019-037(0):101450.
PMID: 31039485
Species: Human
Sample Types: Whole Cells
Applications: ICC

H Hosseini F et al. (2019-04-23), Generation of a heterozygous COL1A1 (c.3969_3970insT) osteogenesis imperfecta mutation human iPSC line, MCRIi001-A-1, using CRISPR/Cas9 editing Stem Cell Res, 2019-037(0):101449.
PMID: 31075690
Species: Human
Sample Types: Whole Cells
Applications: ICC

RMJ Genga et al. (2019-04-16), Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development Cell Rep, 2019-027(3):708-718.e10.
PMID: 30995470
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Vallejo-Di et al. (2019-04-15), Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene Stem Cell Res, 2019-037(0):101440.
PMID: 31026686
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

WK Au Yeung et al. (2019-04-02), Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection Cell Rep, 2019-027(1):282-293.e4.
PMID: 30943408
Species: Human
Sample Types: Liver hiPSCs
Applications: ICC

T Minami et al. (2019-03-30), Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold Regen Ther, 2019-010(0):127-133.
PMID: 31032388
Species: Human
Sample Types: Whole Cells
Applications: ICC

M Suga et al. (2019-02-12), Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I Stem Cell Res, 2019-036(0):101406.
PMID: 30849633
Species: Human
Sample Types: Whole Cells
Applications: ICC

U Diekmann et al. (2019-01-30), Chemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture Sci Rep, 2019-09(1):996.
PMID: 30700818
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr

X Wang et al. (2019-01-09), Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale PeerJ, 2019-06(0):e6143.
PMID: 30643676
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

W Zhang et al. (2019-01-03), The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation Cell Stem Cell, 2019-024(1):138-152.e8.
PMID: 30609396
Species: Human
Sample Types: Whole Cells
Applications: ICC

TR Broda et al. (2019-01-01), Generation of human antral and fundic gastric organoids from pluripotent stem cells Nat Protoc, 2019-014(1):28-50.
PMID: 30470820
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Schuster et al. (2018-12-21), Generation of a homozygous CRISPR/Cas9-mediated knockout human iPSC line for the STUB1 locus Stem Cell Res, 2018-134(0):101378.
PMID: 30605842
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

S Frank et al. (2018-12-13), yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs Cell Stem Cell, 2018-10(0).
PMID: 30554961
Species: Human
Sample Types: Whole Cells
Applications: ICC

JA Maguire et al. (2018-12-10), Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene Stem Cell Res, 2018-134(0):101361.
PMID: 30611021
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Baulier E et al. (2018-11-28), Generation of a human Ocular Albinism type 1 iPSC line, SEIi001-A, with a mutation in GPR143. Stem Cell Res, 2018-133(0):274-277.
PMID: 30513407
Species: Human
Sample Types: Whole Cells
Applications: ICC

T Zhou et al. (2018-11-16), A hPSC-based platform to discover gene-environment interactions that impact human ?-cell and dopamine neuron survival Nat Commun, 2018-19(1):4815.
PMID: 30446643
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Vallejo-Di et al. (2018-11-01), Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient Stem Cell Res, 2018-133(0):180-184.
PMID: 30408744
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Immunoprecipitation

X Wang et al. (2018-10-24), SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh Nat Commun, 2018-19(1):4421.
PMID: 30356064
Species: Human
Sample Types: Whole Cells
Applications: ICC

A Yoney et al. (2018-10-12), WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids Elife, 2018-17(0).
PMID: 30311909
Species: Human
Sample Types: Whole Cells
Applications: ICC

M Holliday et al. (2018-10-06), Generation of an induced pluripotent stem cell line from a hypertrophic cardiomyopathy patient with a pathogenic myosin binding protein C (MYBPC3) p.Arg502Trp mutation Stem Cell Res, 2018-133(0):56-59.
PMID: 30316040
Species: Human

S Vallejo et al. (2018-09-22), Generation of two induced pluripotent stem cells lines from Mucopolysaccharydosis IIIA patient: IMEDEAi004-A and IMEDEAi004-B Stem Cell Res, 2018-032(0):110-114.
PMID: 30269021
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: ICC

R Nakai et al. (2018-08-15), Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata) Sci Rep, 2018-08(1):12187.
PMID: 30111816
Species: Human
Sample Types: Whole Tissue
Applications: IHC

Y Arioka et al. (2018-08-10), Three lines of induced pluripotent stem cells derived from a 15q11.2-q13.1 duplication syndrome patient Stem Cell Res, 2018-031(0):240-243.
PMID: 30144654
Species: Human
Sample Types: Whole Cells
Applications: ICC

X Gao et al. (2018-07-27), Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel Stem Cell Res, 2018-031(0):193-196.
PMID: 30099336
Species: Human
Sample Types: Whole Cells
Applications: ICC

AL Gagne et al. (2018-07-05), Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL Stem Cell Res, 2018-031(0):157-160.
PMID: 30096712
Species: Mouse
Sample Types: Whole Cells
Applications: IHC

K Adachi et al. (2018-06-14), Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency Cell Stem Cell, 2018-00(0).
PMID: 29910149
Species: Human
Sample Types: Whole Cells
Applications: ICC

F Zambelli et al. (2018-06-14), Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stemï¿½Cells Stem Cell Reports, 2018-00(0).
PMID: 29910126
Species: Human
Sample Types: Whole Cells
Applications: ICC

SY Lee et al. (2018-06-09), Generation of gene-corrected iPSC line from Parkinson's disease patient iPSC line with alpha-SNCA A53T mutation Stem Cell Res, 2018-030(0):145-149.
PMID: 29906669
Species: Human
Sample Types: Whole Cells
Applications: IHC

Y Arioka et al. (2018-05-19), Induced pluripotent stem cells derived from a schizophrenia patient with ASTN2 deletion Stem Cell Res, 2018-030(0):81-84.
PMID: 29803967
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

JJ Zylicz et al. (2018-05-10), G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst Elife, 2018-07(0).
PMID: 29745895
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Schuster et al. (2018-04-09), Establishment of STUB1/CHIP mutant induced pluripotent stem cells (iPSCs) from a patient with Gordon Holmes syndrome/SCAR16 Stem Cell Res, 2018-029(0):166-169.
PMID: 29679845
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

NS Corsini et al. (2018-04-05), Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation Cell Stem Cell, 2018-022(4):543-558.e12.
PMID: 29625069
Species: Human
Sample Types: Whole Cells
Applications: IHC

A Sevilla et al. (2018-03-31), Derivation and characterization of the NIH registry human stem cell line NYSCF100 line under defined feeder-free conditions Stem Cell Res, 2018-029(0):99-102.
PMID: 29631040
Species: Human
Sample Types: Whole Cells
Applications: ICC

A Fleischer et al. (2018-03-11), Generation of two induced pluripotent stem cell (iPSC) lines from p.F508del Cystic Fibrosis patients Stem Cell Res, 2018-029(0):1-5.
PMID: 29554588
Species: Mouse
Sample Types: Whole Cells,Whole Tissue
Applications: IHC,ICC

X Han et al. (2018-02-22), Mapping the Mouse Cell Atlas by Microwell-Seq Cell, 2018-0172(5):1091-1107.e17.
PMID: 29474909
Species: Mouse
Sample Types: Whole Cells
Applications: IHC-P

IK Kim et al. (2018-02-14), Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality J. Exp. Med., 2018-00(0).
PMID: 29444818
Species: Human
Sample Types: Embryoid Bodies
Applications: ICC

MT De Angelis et al. (2018-01-05), Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells Cell Death Dis, 2018-09(1):6.
PMID: 29305588
Species: Human
Sample Types: Whole Cells
Applications: ICC

S Martins et al. (2017-12-13), Lymphoblast-derived integration-free ISRM-CON9 iPS cell line from a 75year old female Stem Cell Res, 2017-126(0):76-79.
PMID: 29268155
Species: Human
Sample Types: Whole Cells
Applications: ICC

H Kim et al. (2017-12-06), Generation of a PXR reporter human induced pluripotent stem cell line (PXR-mCherry hiPSC) using the CRISPR/Cas9 system Stem Cell Res, 2017-126(0):72-75.
PMID: 29247817
Species: Human
Sample Types: Whole Cells
Applications: ICC

JP Matson et al. (2017-11-17), Rapid DNA replication origin licensing protects stem cell pluripotency Elife, 2017-16(0).
PMID: 29148972
Species: Human
Sample Types: Whole Cells
Applications: ICC

N Yahata et al. (2017-11-14), TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation Sci Rep, 2017-17(1):15557.
PMID: 29138463
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

M Wigger et al. (2017-11-09), Plasticity of the inner cell mass in mouse blastocyst is restricted by the activity of FGF/MAPK pathway Sci Rep, 2017-17(1):15136.
PMID: 29123210
Species: Human
Sample Types: Whole Cells
Applications: ICC

CY Yu et al. (2017-10-27), The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency Nat Commun, 2017-18(1):1149.
PMID: 29074849
Species: Mouse
Sample Types: Embryo
Applications: IHC-Fr

M Gialitakis et al. (2017-10-26), Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development Stem Cell Reports, 2017-19(5):1377-1386.
PMID: 29107595
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

S Bessonnard et al. (2017-09-25), ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation Sci Rep, 2017-07(1):12285.
PMID: 28947813
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

CJ Walker et al. (2017-08-12), Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations Oncotarget, 2017-08(40):68758-68768.
PMID: 28978154
Species: Human
Sample Types: Whole Cells
Applications: ICC

Y Hosokawa et al. (2017-08-10), Insulin-producing cells derived from 'induced pluripotent stem cells' of patients with fulminant type 1 diabetes: vulnerability to cytokine insults and increased expression of apoptosis-related genes J Diabetes Investig, 2017-00(0).
PMID: 28796422
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

M Sambi et al. (2017-08-01), Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors Stem Cell Rev, 2017-00(0).
PMID: 28239758
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

X Li et al. (2017-06-22), Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State Cell Stem Cell, 2017-00(0).
PMID: 28648365
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot

T Kobayashi et al. (2017-06-07), Principles of early human development and germ cell program from conserved model systems Nature, 2017-0546(7658):416-420.
PMID: 28607482
Species: Human
Sample Types: Whole Tissue
Applications: IHC

MA Lancaster et al. (2017-05-31), Guided self-organization and cortical plate formation in human brain organoids Nat. Biotechnol., 2017-00(0).
PMID: 28562594
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

M Kang et al. (2017-05-25), Lineage Establishment and Progression within the Inner Cell Mass of the Mouse Blastocyst Requires FGFR1 and FGFR2 Dev. Cell, 2017-00(0).
PMID: 28552559
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

A Molotkov et al. (2017-05-25), Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency Dev. Cell, 2017-00(0).
PMID: 28552557
Species: Human
Sample Types: Embryoid Bodies
Applications: Flow Cytometry

A Arauchi et al. (2017-05-22), Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture Front Endocrinol (Lausanne), 2017-08(0):103.
PMID: 28588551
Species: Human,Mouse
Sample Types: Whole Cells
Applications: ICC

Y Kondo et al. (2017-05-22), Identification of a small molecule that facilitates the differentiation of human iPSCs/ESCs and mouse embryonic pancreatic explants into pancreatic endocrine cells Diabetologia, 2017-00(0).
PMID: 28534195
Species: Human
Sample Types: Whole Cells
Applications: ICC

Q Gu et al. (2017-05-11), Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations Stem Cell Reports, 2017-00(0).
PMID: 28506532
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

H Higashiyam et al. (2017-04-21), Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient model of biliary atresia Development, 2017-00(0).
PMID: 28432216
Species: Human
Sample Types: Whole Cells
Applications: ICC

J Saarimäki- et al. (2017-04-11), An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation Cell Rep, 2017-019(2):281-294.
PMID: 28402852
Species: Human
Sample Types: Whole Cells
Applications: ICC

F Sampazioti et al. (2017-03-23), Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells Nat Protoc, 2017-012(4):814-827.
PMID: 28333915
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

M Goolam et al. (2017-03-13), The chromatin modifier Satb1 regulates cell fate through Fgf signalling in the early mouse embryo Development, 2017-00(0).
PMID: 28289135
Species: Human
Sample Types: Whole Tissue
Applications: IHC

SB Ross et al. (2017-03-07), Peripheral blood derived induced pluripotent stem cells (iPSCs) from a female with familial hypertrophic cardiomyopathy Stem Cell Res, 2017-020(0):76-79.
PMID: 28395744
Species: Human
Sample Types: Whole Cells
Applications: ICC

LC Lewis et al. (2017-03-07), Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification Epigenetics, 2017-00(0):0.
PMID: 28267381
Species: Human
Sample Types: Whole Cells
Applications: ICC

SB Ross et al. (2017-03-07), Generation of induced pluripotent stem cells (iPSCs) from a hypertrophic cardiomyopathy patient with the pathogenic variant p.Val698Ala in beta-myosin heavy chain (MYH7) gene Stem Cell Res, 2017-020(0):88-90.
PMID: 28395747
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

M Borensztei et al. (2017-01-30), Xist-dependent imprinted X inactivation and the early developmental consequences of its failure Nat. Struct. Mol. Biol, 2017-00(0).
PMID: 28134930
Species: Human
Sample Types: Whole Cells
Applications: ICC

C Lorenz et al. (2017-01-26), Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders Cell Stem Cell, 2017-00(0).
PMID: 28132834
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

(2016-12-19), Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos Sci Rep, 2016-16(0):39457.
PMID: 27991575
Species: Human
Sample Types: Whole Cells
Applications: ICC

N Zeltner et al. (2016-11-14), Capturing the biology of disease severity in a PSC-based model of familial dysautonomia Nat. Med., 2016-122(12):1421-1427.
PMID: 27841875
Species: Human
Sample Types: Whole Cells
Applications: IHC-P

(2016-11-01), Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells PLoS ONE, 2016-111(11):e0165715.
PMID: 27802323
Species: Rat
Sample Types: Whole Cells
Applications: IHC

(2016-10-31), Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury Sci Rep, 2016-16(0):36077.
PMID: 27796316
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr

(2016-09-17), Generation of optic atrophy 1 patient-derived induced pluripotent stem cells (iPS-OPA1-BEHR) for disease modeling of complex optic atrophy syndromes (Behr syndrome) Stem Cell Res, 2016-017(2):426-429.
PMID: 27879217
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

(2016-09-01), p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development Open Biol, 2016-06(9).
PMID: 27605380
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr

(2016-07-20), Diverse Functions of Retinoic Acid in Brain Vascular Development J Neurosci, 2016-036(29):7786-801.
PMID: 27445154
Species: Human
Sample Types: Whole Cells
Applications: IHC

Claudia Davenport (2016-07-04), The Anterior-Posterior Patterning of Definitive Endoderm Generated from Human Embryonic Stem Cells Depends on the Differential Signaling of Retinoic Acid, Wnt- and BMP-Signaling Stem Cells, 2016-00(0).
PMID: 27299363
Species: Mouse
Sample Types: Whole Cells
Applications: IHC

Hyun Sik Jang (2016-05-27), Changes in Parthenogenetic Imprinting Patterns during Reprogramming by Cell Fusion PLoS ONE, 2016-011(5):e0156491.
PMID: 27232503
Species: Mouse
Sample Types: Whole Cells
Applications: IHC

(2016-05-24), Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation Sci Rep, 2016-06(0):26562.
PMID: 27217206
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,IHC

A Carpentier et al. (2016-03-29), Hepatic differentiation of human pluripotent stem cells in miniaturized format suitable for high-throughput screen Stem Cell Res, 2016-016(3):640-650.
PMID: 27062358
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Alexandrova S et al. (2015-11-19), Selection and dynamics of embryonic stem cell integration into early mouse embryos. Development, 2015-1143(1):24-34.
PMID: 26586221
Species: Human
Sample Types: Whole Tissue
Applications: IHC

Takasato M et al. (2015-10-07), Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 2015-1526(7574):564-8.
PMID: 26444236
Species: Human
Sample Types: Whole Cells
Applications: IHC

Nagaoka M et al. (2015-08-26), Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells. PLoS ONE, 2015-010(8):e0136350.
PMID: 26308339
Species: Human
Sample Types: Whole Cells
Applications: IHC

Paull D et al. (2015-08-03), Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells. Nat Methods, 2015-012(9):885-92.
PMID: 26237226
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot

Yoon et al. (2015-03-16), HEB associates with PRC2 and SMAD2/3 to regulate developmental fates. Nat Commun, 2015-06(0):6546.
PMID: 25775035
Species: Human
Sample Types: Whole Cells
Applications: ICC

Kim M et al. (2015-02-23), Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis. PLoS ONE, 2015-010(2):e0118670.
PMID: 25706534
Species: Mouse
Sample Types: Embryo
Applications: IHC

Krawchuk D et al. (2015-01-14), Loss of LKB1 leads to impaired epithelial integrity and cell extrusion in the early mouse embryo. J Cell Sci, 2015-0128(5):1011-22.
PMID: 25588837
Species: Human
Sample Types: Whole Cells
Applications: IHC

Cerbini T et al. (2015-01-14), Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines. PLoS ONE, 2015-010(1):e0116032.
PMID: 25587899
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Graham et al. (2014-12-16), BMP signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo. Nat Commun, 2014-15(0):5667.
PMID: 25514175
Species: Mouse
Sample Types: Whole Cells
Applications: IHC

Xu H et al. (2014-08-04), Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and beta-catenin signaling. J Biol Chem, 2014-0289(38):26290-301.
PMID: 25092289
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Schrode N et al. (2014-05-15), GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst. Dev Cell, 2014-029(4):454-67.
PMID: 24835466
Species: Human
Sample Types: Whole Cells
Applications: ICC

Kishino et al. (2014-05-13), Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions. PLoS ONE, 2014-09(5):e97397.
PMID: 24824994
Species: Human
Sample Types: Whole Cells
Applications: IHC

Takahashi K et al. (2014-04-24), Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm. Nat Commun, 2014-05(0):3678.
PMID: 24759836
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Tsukiyama et al. (2014-04-15), A modified EpiSC culture condition containing a GSK3 inhibitor can support germline-competent pluripotency in mice. PLoS ONE, 2014-09(4):e95329.
PMID: 24736627
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Shimamoto R et al. (2014-04-09), Generation and characterization of induced pluripotent stem cells from Aid-deficient mice. PLoS ONE, 2014-09(4):e94735.
PMID: 24718089
Species: Human
Sample Types: Whole Cells
Applications: ICC

Rosa A et al. (2014-04-04), miR-373 is regulated by TGFbeta signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells. Dev Biol, 2014-0391(1):81-8.
PMID: 24709321
Species: Mouse
Sample Types: Embryo
Applications: IHC

Nobuhisa I et al. (2014-03-24), Sox17-mediated maintenance of fetal intra-aortic hematopoietic cell clusters. Mol Cell Biol, 2014-034(11):1976-90.
PMID: 24662049
Species: Human
Sample Types: Whole Cells
Applications: ICC

Hakim F et al. (2014-02-19), High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells. J Biol Chem, 2014-0289(14):9623-38.
PMID: 24554704
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Christophorou M et al. (2014-01-26), Citrullination regulates pluripotency and histone H1 binding to chromatin. Nature, 2014-0507(7490):104-8.
PMID: 24463520
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Sherwood et al. (2014-01-19), Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape. Nat Biotechnol, 2014-032(2):171-8.
PMID: 24441470
Species: Human
Sample Types: Whole Cells
Applications: ICC

Massumi M et al. (2014-01-13), Efficient programming of human eye conjunctiva-derived induced pluripotent stem (ECiPS) cells into definitive endoderm-like cells. Exp Cell Res, 2014-0322(1):51-61.
PMID: 24434355
Species: Human
Sample Types: Cell Culture Supernates
Applications: Flow Cytometry

Cechin S et al. (2013-12-27), Influence of in vitro and in vivo oxygen modulation on beta cell differentiation from human embryonic stem cells. Stem Cells Transl Med, 2013-13(3):277-89.
PMID: 24375542
Species: Human
Sample Types: Whole Cells
Applications: ICC

Singh A et al. (2013-12-05), Cell-cycle control of developmentally regulated transcription factors accounts for heterogeneity in human pluripotent cells. Stem Cell Reports, 2013-11(6):532-44.
PMID: 24371808
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Kaitsuka T et al. (2013-11-29), Generation of functional insulin-producing cells from mouse embryonic stem cells through 804G cell-derived extracellular matrix and protein transduction of transcription factors. Stem Cells Transl Med, 2013-13(1):114-27.
PMID: 24292793
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Yamamizu K et al. (2013-11-27), Identification of transcription factors for lineage-specific ESC differentiation. Stem Cell Reports, 2013-11(6):545-59.
PMID: 24371809
Species: Mouse
Sample Types: Cell Lysates,Whole Cells
Applications: Western Blot,ICC

Taylor-Weiner H et al. (2013-10-01), Defined extracellular matrix components are necessary for definitive endoderm induction. Stem Cells, 2013-131(10):2084-94.
PMID: 23766144
Species: Human
Sample Types: Whole Cells
Applications: ICC

Hannan et al. (2013-01-01), Production of hepatocyte-like cells from human pluripotent stem cells. Nat Protoc, 2013-08(2):430-7.
PMID: 23370178
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Sneddon et al. (2012-10-07), Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature, 2012-1491(7426):765-8.
PMID: 23041930
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Soh et al. (2012-09-11), CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. Mol Ther, 2012-020(12):2335-46.
PMID: 22968480
Species: Mouse
Sample Types: Whole Tissue,Cell Lysates
Applications: Western Blot,IHC-Fr

Wang P et al. (2012-02-29), A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. Stem Cells Dev, 2012-021(12):2273-87.
PMID: 22236333
Species: Human
Sample Types: Whole Cells

Joubin et al. (2012-02-21), The endothelial cell line bEnd.3 maintains human pluripotent stem cells. Stem Cells Dev, 2012-021(12):2312-21.
PMID: 22224974
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Tajbakhsh J et al. (2011-07-14), Early in vitro differentiation of mouse definitive endoderm is not correlated with progressive maturation of nuclear DNA methylation patterns. PLoS ONE, 2011-06(7):e21861.
PMID: 21779341
Species: Human
Sample Types: Whole Cells
Applications: ICC

Bone HK et al. (2011-05-24), A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3. J. Cell. Sci., 2011-0124(0):1992-2000.
PMID: 21610099
Species: Human
Sample Types: Whole Cells
Applications: ICC

Jiang W et al. (2011-04-01), CD24: a novel surface marker for PDX1-positive pancreatic progenitors derived from human embryonic stem cells. Stem Cells, 2011-029(4):609-17.
PMID: 21308865
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Artus J et al. (2010-09-08), A role for PDGF signaling in expansion of the extra-embryonic endoderm lineage of the mouse blastocyst. Development, 2010-0137(20):3361-72.
PMID: 20826533
Species: Human
Sample Types: Whole Cells
Applications: ICC

Emre N et al. (2010-08-13), The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers. PLoS ONE, 2010-05(8):e12148.
PMID: 20730054
Species: Human
Sample Types: Whole Cells
Applications: ICC

Oda Y et al. (2010-07-01), Induction of pluripotent stem cells from human third molar mesenchymal stromal cells. J. Biol. Chem., 2010-0285(38):29270-8.
PMID: 20595386
Species: Human
Sample Types: Whole Cells
Applications: ICC

Morris SA et al. (2010-03-22), Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo. Proc. Natl. Acad. Sci. U.S.A., 2010-0107(14):6364-9.
PMID: 20308546
Species: Human
Sample Types: Whole Cells
Applications: ICC

Chng Z et al. (2010-01-08), SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells. Cell Stem Cell, 2010-06(1):59-70.
PMID: 20074535
Species: Human
Sample Types: Cell Lysates,Whole Cells
Applications: ICC,Western Blot

Chayosumrit M et al. (2009-10-14), Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm. Biomaterials, 2009-131(3):505-14.
PMID: 19833385
Species: Human
Sample Types: Whole Cells
Applications: ICC

Sun N et al. (2009-09-08), Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proc. Natl. Acad. Sci. U.S.A., 2009-0106(37):15720-5.
PMID: 19805220
Species: Mouse
Sample Types: Whole Cells
Applications: ICC

Hansson M et al. (2009-04-07), A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells. Dev. Biol., 2009-0330(2):286-304.
PMID: 19358838
Species: Mouse,Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICC

Borowiak M et al. (2009-04-03), Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell, 2009-04(4):348-58.
PMID: 19341624
Species: Human
Sample Types: Whole Cells
Applications: ICC

Zhang D et al. (2009-04-01), Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res., 2009-019(4):429-38.
PMID: 19255591
Species: Human,Mouse
Sample Types: Whole Cells
Applications: ICC

Bernardo AS et al. (2009-02-01), Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells. Stem Cells, 2009-027(2):341-51.
PMID: 19056911
Species: Human
Sample Types: Whole Cells
Applications: ICC

Gil JE et al. (2009-01-20), Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells. FEBS Lett., 2009-0583(3):561-7.
PMID: 19162023
Species: Human
Sample Types: Whole Cells
Applications: Neutralization,ICC

Desbordes SC et al. (2008-06-05), High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell, 2008-02(6):602-12.
PMID: 18522853
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC

Sherwood RI et al. (2007-01-12), Prospective isolation and global gene expression analysis of definitive and visceral endoderm. Dev. Biol., 2007-0304(2):541-55.
PMID: 17328885
Species: Human
Sample Types: Whole Cells
Applications: ICC

Yao S et al. (2006-04-21), Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc. Natl. Acad. Sci. U.S.A., 2006-0103(18):6907-12.
PMID: 16632596

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Customer Reviews for Human SOX17 Antibody (16)

4.8 out of 5

16 customer ratings

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Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: mouse retina

Species: Mouse

Verified Customer | Posted 05/20/2023

1:1000 works well in the mouse retina
Human SOX17 Antibody

Name: Anonymous

Application: Immunohistochemistry

Sample Tested: Umbilical vein endothelial cells and BG01V human embryonic stem cells

Species: Human

Verified Customer | Posted 08/15/2022

Cells where fixed, permeated, and stained with 1:200 SOX17 antibody from R&D, followed by a 594 alexa fluora secondary antibody.
Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: iPSCs

Species: Human

Verified Customer | Posted 05/01/2022

1:500 dilution, localized in the nucleus.
Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: Cells from hematopoietic differentiation of hESC line H9

Species: Human

Verified Customer | Posted 03/30/2022
Human SOX17 Antibody

Name: Anonymous

Application: Immunohistochemistry

Sample Tested: Melanoma tissue

Species: Human

Verified Customer | Posted 11/17/2021

Tissue section was cryopreserved, not FFPE
Human SOX17 Antibody

Name: Ricardo Malvicini

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: differentiating organoid from human iPSC and differentiating organoid

Species: Human

Verified Customer | Posted 10/28/2021
Human SOX17 Antibody

Name: Anonymous

Application: single cells from a ESC to endoderm induction

Sample Tested: D3 mouse embryonic stem cell line

Species: Mouse

Verified Customer | Posted 10/22/2021
Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: retinal cells

Species: Human

Verified Customer | Posted 09/23/2021

1:200 dilution works good in immunocytochemistry
Human SOX17 Antibody

Name: Anonymous

Application: It works very well.

Sample Tested: Cerebral nerve cells and Brain (cerebral cortex)

Species: Human

Verified Customer | Posted 08/23/2021

1:200 dilution
Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: Differentiated embryonic stem cells

Species: Human

Verified Customer | Posted 10/15/2020

Permeabilised with 0.5% Triton + 0.1% BSA Blocked with 0.1% BSA/ 10% FCS as blocking agent for 1 hour at RT Primary was added at 1:20 in blocking buffer and incubated o/n at 4oC.
Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: Differentiated embryonic stem cells

Species: Human

Verified Customer | Posted 04/15/2019

SOX17 antibody was used to assess the efficient differentiation of hESCs towards Definitive endoderm cells were fixed by adding 4%PFA for 15min blocking buffer contained 10%FCS, 0.1% BSA in PBS For permeabilisation 0.5% Triton X-100 was used Antibody was used at 10mg/ml and left o/n at 4oC
Human SOX17 Antibody

Name: Leslie Priddy

Application: Western Blot

Sample Tested: Tumor cell lyastes

Species: Human

Verified Customer | Posted 04/13/2018
Human SOX17 Antibody

Name: Anonymous

Application: Immunocytochemistry/Immunofluorescence

Sample Tested: Endoderm and Induced Pluripotent Stem Cells

Species: Human

Verified Customer | Posted 12/15/2016

Used this antibody to verify the endodermal germ layer derived from iPSC.
Name: Anonymous -

Application: Immunofluorescence

Sample Tested: See PMIC 23658023

Species: Human

Verified Customer | Posted 01/05/2015
Name: Anonymous -

Application: Immunofluorescence

Sample Tested: See PMIC 22613812

Species: Human

Verified Customer | Posted 01/05/2015
Name: Anonymous -

Application: Immunofluorescence

Sample Tested: See PMIC 23418163

Species: Other

Verified Customer | Posted 01/05/2015

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Catalog # AF1924 | R&D Systems, Inc. a Bio-Techne Brand

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Detection of Human SOX17 by Western Blot.

Detection of SOX17-regulated Genes by Chromatin Immunoprecipitation.

SOX17 in B16 Mouse Cell Line.

SOX17 in Human BG01V Cells.

Detection of Human SOX17 by Simple WesternTM.

Detection of Human SOX17 by Simple WesternTM.

Detection of Human SOX17 by Western Blot.

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Citations for Human SOX17 Antibody (289)

Customer Reviews for Human SOX17 Antibody (16)

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Detection of Human SOX17 by Simple Western^TM.

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