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Human PTGER2 Alexa Fluor™ Plus 680-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB6656AFP680

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FAB6656AFP680-100UG

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Alexa Fluor Plus 680 (Excitation = 687 nm, Emission = 704 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 607077

Product Specifications

Specificity

Detects human PTGER2 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human PTGER2 Alexa Fluor™ Plus 680-conjugated Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Background: PTGER2

Prostaglandin E2 receptor (PTGER2) is a 53 kDa member of the G-protein coupled receptor family of proteins. Human PTGER2 is 358 amino acids (aa) in length and has the seven putative transmembrane domains characteristic of G-protein coupled receptors. In addition, there are four potential sites for N-linked glycosylation.  Human PTGER2 shares 86% and 83% aa sequence identity with mouse and rat PTGER2, respectively. PTGER2 is present in the vasculature, the gastrointestinal, tracheobronchial, and reproductive tracts, the kidney, and also in the sphincter, dilator, and ciliary muscles in the eye.  PTGER2 is linked to prostaglandin E2-mediated vasodilation and smooth muscle relaxation. It is also involved in the stimulation of secretion in the stomach and small intestine, the control of intraocular pressure, and the regulation of bone resorption.

Long Name

Prostaglandin E2 Receptor 2, Subtype EP2

Alternate Names

EP2

Entrez Gene IDs

5732 (Human); 19217 (Mouse); 81752 (Rat)

Gene Symbol

PTGER2

UniProt

Additional PTGER2 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human PTGER2 Alexa Fluor™ Plus 680-conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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