Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody

Name: Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody
Brand: R&D Systems
SKU: IC2018V
Price: 388 USD

R&D Systems, Inc. a Bio-Techne Brand

Catalog # IC2018V

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Key Product Details

Species Reactivity:	Human, Mouse, Rat
Immunogen:	E. coli-derived recombinant human SOX2 Gly135-Met317 Accession # P48431
Applications:	Flow Cytometry
Label:	Alexa Fluor 405 (Excitation=405 nm, Emission=421 nm)
Specificity:	Detects human, mouse, and rat SOX2 in Western blots.

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Applications for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody

	Recommended Concentration	Sample
Intracellular Staining by Flow Cytometry	0.25-1 µg/10⁶ cells	NTera‑2 human embryonic carcinoma cell line fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005)

Please Note: Optimal dilutions should be determined by each laboratory for each application.

Formulation, Preparation and Storage

Formulation	Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

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Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Background: SOX2

SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-6).

Item	Value
References	Graham, V. et al. (2003) Neuron 39:749. Avilion, A.A. et al. (2003) Genes Dev. 17:126. Kishi, M. et al. (2000) Development 127:791. Yuan, H. et al. (1995) Genes Dev. 9:2635. Uwanogho, D. et al. (1995) Mech. Dev. 49:23. Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Long Name	Transcription Factor SOX2
Entrez Gene IDs	6657 (Human)
Alternate Names	ANOP3, MCOPS3, MGC2413, SOX2, SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, transcription factor SOX-2, transcription factor SOX2

Product Specific Notices for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

Citations for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody (1)

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Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody include:

Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry

M Zloh et al. (2022), High-Contrast Stimulation Potentiates the Neurotrophic Properties of Mï¿½ller Cells and Suppresses Their Pro-Inflammatory Phenotype International Journal of Molecular Sciences, 23(15).
PMID: 35955747

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Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody

R&D Systems, Inc. a Bio-Techne Brand

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Applications for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody

Formulation, Preparation and Storage

Plan Your Experiments

Reconstitution Calculator

Background: SOX2

Product Specific Notices for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody

Citations for Human/Mouse/Rat SOX2 Alexa Fluor® 405-conjugated Antibody (1)

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