Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody
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Key Product Details
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Peptide corresponding to residues EEEDSTALVC of the N-term of human alpha -smooth muscle actin (1) |
Applications: | CyTOF-ready, Dual RNAscope ISH-IHC, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
Label: | Unconjugated |
Source: | Monoclonal Mouse IgG2A Clone # 1A4 |
Specificity: |
Detects human alpha -Smooth Muscle Actin. |
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Citations for Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody (71)
Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse/Rat alpha -Smooth Muscle Actin Antibody include:
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Species: Rabbit
Sample Types: Whole Tissue
Applications: IHCZ Li et al. (2022), Synergistic effects of silver nanoparticles and cisplatin in combating inflammation and hyperplasia of airway stents Bioactive materials, 9(0):266-280.
PMID: 34820570 -
Species: Human
Sample Types: Whole Cells
Applications: CyTofTB Layton et al. (2022), A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease Proceedings of the National Academy of Sciences of the United States of America, 119(13):e2120336119.
PMID: 35320046 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMAS de Toledo et al. (2022), CRISPR/Cas9-engineered human ES cells harboring heterozygous and homozygous c-KIT knockout Stem Cell Research, 60(0):102732.
PMID: 35279545 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSF Mause et al. (2022), Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis International Journal of Molecular Sciences, 23(2).
PMID: 35055054 -
Species: Mouse
Sample Types: Spheroids
Applications: ICCT Kazi et al. (2022), Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via beta-Catenin Activation Cells, 11(2).
PMID: 35053317 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryJWS Jahng et al. (2021), Generation of three induced pluripotent stem cell lines, SCVIi003-A, SCVIi004-A, SCVIi005-A, from patients with ARVD/C caused by heterozygous mutations in the PKP2 gene Stem Cell Research, 53(0):102284.
PMID: 33743362 -
Species: Human
Sample Types: Whole Cells
Applications: ICCJ Geuder et al. (2021), A non-invasive method to generate induced pluripotent stem cells from primate urine Scientific Reports, 11(1):3516.
PMID: 33568724 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCC Jaworek et al. (2021), Cohort Analysis of ADAM8 Expression in the PDAC Tumor Stroma Journal of personalized medicine, 11(2).
PMID: 33578644 -
Species: Human
Sample Types: Whole Cells
Applications: ICCY Wang et al. (2021), Cancer-associated fibroblast-derived SDF-1 induces epithelial-mesenchymal transition of lung adenocarcinoma via CXCR4/&beta-catenin/PPAR&delta signalling Cell Death Disease, 2021;12(2):214.
PMID: 33637678 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryY Luo et al. (2021), Generation of an induced pluripotent stem cell line GZHMCi008-A derived from a patient with SRY-positive 46,XX testicular disorder of sex development Stem Cell Research, 57(0):102583.
PMID: 34710837 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotK Hira et al. (2021), Cyclo(Val-Pro) and Cyclo(Leu-Hydroxy-Pro) from Pseudomonas sp. (ABS-36) alleviates acute and chronic renal injury under in vitro and in vivo models (Ischemic reperfusion and unilateral ureter obstruction) International immunopharmacology, 103(0):108494.
PMID: 34973530 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotMR Vitale et al. (2021), Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelopmental disorders using CRISPR/Cas9 Stem Cell Research, 51(0):102169.
PMID: 33486346 -
Species: Rat
Sample Types: Tissue Homogenates
Applications: Western BlotRS Lindoso et al. (2020), Adipose Mesenchymal Cells-Derived EVs Alleviate DOCA-Salt-Induced Hypertension by Promoting Cardio-Renal Protection Mol Ther Methods Clin Dev, 16(0):63-77.
PMID: 31871958 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCX Li et al. (2020), Dynamic Changes in Function and Proteomic Composition of Extracellular Vesicles from Hepatic Stellate Cells during Cellular Activation Cells, 9(2).
PMID: 31991791 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCC Liang et al. (2020), CD8+ T-cell plasticity regulates vascular regeneration in type-2 diabetes Theranostics, 10(9):4217-4232.
PMID: 32226549 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCL Jin et al. (2020), STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells Nat Commun, 11(1):5941.
PMID: 33230114 -
Species: Rat
Sample Types: Whole Tissue
Applications: IHCBB Patai et al. (2020), Initiation of reticular and spider veins, incompetent perforantes and varicose veins in the saphenous vein network of the rat Scientific Reports, 10(1):15381.
PMID: 32958828 -
Species: Human
Sample Types: Whole Cells
Applications: CyTofTB Layton et al. (2020), Cellular census of human fibrosis defines functionally distinct stromal cell types and states Nat Commun, 11(1):2768.
PMID: 32488016 -
Species: Human
Sample Types: Whole Tissues
Applications: IHCS Ashwinbala et al. (2020), SB772077B (SB77) Alleviated the Aqueous Outflow Resistance Mediated by Cyclic Mechanical Stress in Perfused Human Cadaveric Eyes Sci Rep, 10(1):10202.
PMID: 32576873 -
Species: Rat
Sample Types: Whole Tissues
Applications: IHCTT Ross et al. (2020), Acetyl-CoA Carboxylase inhibition improves multiple dimensions of NASH pathogenesis in model systems Cell Mol Gastroenterol Hepatol, 0(0).
PMID: 32526482 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotA Kanda et al. (2019), TGF-?-SNAIL axis induces M�ller glial-mesenchymal transition in the pathogenesis of idiopathic epiretinal membrane Sci Rep, 9(1):673.
PMID: 30679596 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCT Masuda et al. (2019), Inhibition of PAI-1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer-associated fibroblasts J. Cell. Mol. Med., 0(0).
PMID: 30734495 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-PCF Guerrero-J et al. (2019), Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds Nat Commun, 10(1):650.
PMID: 30737373 -
Species: Human
Sample Types: Whole Cells
Applications: ICCT Bikkuzin et al. (2019), Human induced pluripotent stem cell line HMUi001-A derived from corneal stromal cells Stem Cell Res, 37(0):101409.
PMID: 31121475 -
Species: Rat
Sample Types: Tissue Homogenates
Applications: Western BlotM Komai et al. (2019), Pathological Study on Epithelial-Mesenchymal Transition in Silicotic Lung Lesions in Rat Vet Sci, 6(3).
PMID: 31480326 -
Species: Human
Sample Types: Whole Cells
Applications: ICCTW Kragstrup et al. (2019), Fibroblast-like synovial cell production of extra domain A fibronectin associates with inflammation in osteoarthritis BMC Rheumatol, 3(0):46.
PMID: 31819923 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotNA Das et al. (2019), Empagliflozin reduces high glucose-induced oxidative stress and miR-21-dependent TRAF3IP2 induction and RECK suppression, and inhibits human renal proximal tubular epithelial cell migration and epithelial-to-mesenchymal transition Cell. Signal., 68(0):109506.
PMID: 31862399 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCT Kazi et al. (2019), Optimal stimulation toward the dermal papilla lineage can be promoted by combined use of osteogenic and adipogenic inducers FEBS Open Bio, 0(0).
PMID: 31730301 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCO Espitia et al. (2018), Implication of molecular vascular smooth muscle cell heterogeneity among arterial beds in arterial calcification PLoS ONE, 13(1):e0191976.
PMID: 29373585 -
Species: Human
Sample Types: Organoids
Applications: IHCJ Barnes et al. (2018), Modeling the neuropsychiatric manifestations of Lowe syndrome using induced pluripotent stem cells: defective F-actin polymerization and WAVE-1 expression in neuronal cells Mol Autism, 9(0):44.
PMID: 30147856 -
Species: Human
Sample Types: Tissue Homogenates
Applications: Western BlotQ Li et al. (2018), Exosomal miR-21-5p derived from gastric cancer promotes peritoneal metastasis via mesothelial-to-mesenchymal transition Cell Death Dis, 9(9):854.
PMID: 30154401 -
S Kaur et al. (2018), Small non-coding RNA landscape of extracellular vesicles from human stem cells Sci Rep, 8(1):15503.
PMID: 30341351 -
Species: Primate - Macaca mulatta (Rhesus Macaques)
Sample Types: Whole Tissue
Applications: IHC-PRB Reisler et al. (2018), Ebola Virus Causes Intestinal Tract Architectural Disruption and Bacterial Invasion in Non-Human Primates Viruses, 10(10).
PMID: 30241284 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMH Kwack et al. (2018), Establishment and characterization of five immortalized human scalp dermal papilla cell lines Biochem. Biophys. Res. Commun., 0(0).
PMID: 29331373 -
Species: Human
Sample Types: Whole Cells
Applications: ICCDE Reichman et al. (2018), Wnt inhibition promotes vascular specification of embryonic cardiac progenitors Development, 145(1).
PMID: 29217753 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSC Hrstka et al. (2017), NOTCH1-dependent nitric oxide signaling deficiency in hypoplastic left heart syndrome revealed through patient-specific phenotypes detected in bioengineered cardiogenesis Stem Cells, 0(0).
PMID: 28142228 -
Species: Human
Sample Types: Whole Cells
Applications: ICCRCB Wong et al. (2017), Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy Aging (Albany NY), 9(4):1341-1350.
PMID: 28455970 -
Species: Rat
Sample Types: Tissue Homogenates
Applications: Western BlotL Zhou et al. (2017), Buyang Huanwu Tang improves denervation-dependent muscle atrophy by increasing ANGPTL4, and increases NF-?B and MURF1 levels Mol Med Rep, 0(0).
PMID: 29257347 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCM Lombardi et al. (2017), P2X7 receptor antagonism modulates IL-1? and MMP9 in human atherosclerotic vessels Sci Rep, 7(1):4872.
PMID: 28687781 -
Species: Human
Sample Types: Whole Cells
Applications: ICCRCB Wong et al. (2017), Generation of a human induced pluripotent stem cell line CERAi001-A-6 using episomal vectors Stem Cell Res, 22(0):13-15.
PMID: 28952926 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotH Kamata et al. (2017), KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis Sci Rep, 7(1):4556.
PMID: 28676645 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCH Takahashi et al. (2017), Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages Oncotarget, 8(5):8633-8647.
PMID: 28052009 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PY Dong et al. (2017), Pathologic Roles of Receptor-Associated Prorenin System in Idiopathic Epiretinal Membrane Sci Rep, 7(0):44266.
PMID: 28276504 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-PDR Smith et al. (2017), Neuropathogenesis of Zika Virus in a Highly Susceptible Immunocompetent Mouse Model after Antibody Blockade of Type I Interferon PLoS Negl Trop Dis, 11(1):e0005296.
PMID: 28068342 -
Species: Human
Sample Types: Whole Cells
Applications: IHCW Qin et al. (2016), Exosomes in Human Breast Milk Promote EMT Clin Cancer Res, 0(0).
PMID: 27060153 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P(2016), The influence of warm ischemia elimination on kidney injury during transplantation - clinical and molecular study Sci Rep, 6(0):36118.
PMID: 27808277 -
Species: Canine
Sample Types: Whole Tissue
Applications: IHCSofia Avnet (2016), Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-?B acivation Int. J. Cancer, 0(0).
PMID: 27888521 -
Species: Mouse
Sample Types: Whole Cells
Applications: IHCJian-Yong Xu (2016), Generation of Induced Cardiospheres via Reprogramming of Skin Fibroblasts for Myocardial Regeneration Stem Cells, 0(0).
PMID: 27333945 -
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry(2016), Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment Cancer Res., 0(0).
PMID: 27864347 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PRiordan D et al. (2015), Automated Analysis and Classification of Histological Tissue Features by Multi-Dimensional Microscopic Molecular Profiling. PLoS ONE, 10(7):e0128975.
PMID: 26176839 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PMartinez L et al. (2015), CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patients. PLoS ONE, 10(3):e0121421.
PMID: 25803686 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCDavaine J et al. (2014), Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS ONE, 9(9):e107642.
PMID: 25259713 -
Species: Human
Sample Types: Whole Cells
Applications: ICCPiao Y et al. (2014), Efficient generation of integration-free human induced pluripotent stem cells from keratinocytes by simple transfection of episomal vectors. Stem Cells Transl Med, 3(0):787-791.
PMID: 24904173 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PDi Caro G et al. (2014), Occurrence of tertiary lymphoid tissue is associated with T-cell infiltration and predicts better prognosis in early-stage colorectal cancers. Clin Cancer Res, 20(8):2147-58.
PMID: 24523438 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PLiu T et al. (2014), Association between PON1 rs662 polymorphism and coronary artery disease. Eur J Clin Nutr, 68(9):1029-35.
PMID: 24918121 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSong S et al. (2013), Distinct transcriptional profiles of angioblasts derived from human embryonic stem cells. Exp Cell Res, 319(8):1136-45.
PMID: 23458169 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blotvan der Veer E et al. (2013), Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype. Circ Res, 113(9):1065-75.
PMID: 23963726 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMilani C et al. (2013), Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture. BMC Cancer, 13(0):119.
PMID: 23497279 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotMohamed SA et al. (2012), Locally different endothelial nitric oxide synthase protein levels in ascending aortic aneurysms of bicuspid and tricuspid aortic valve. Cardiol Res Pract, 2012(0):165957.
PMID: 22745920 -
Species: Rabbit
Sample Types: Whole Tissue
Applications: IHC-POhshima S et al. (2010), Effect of an antimicrobial agent on atherosclerotic plaques: assessment of metalloproteinase activity by molecular imaging. J. Am. Coll. Cardiol., 55(12):1240-9.
PMID: 20298932 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMohamed SA et al. (2010), Inhibition of caspase-3 differentially affects vascular smooth muscle cell apoptosis in the concave versus convex aortic sites in ascending aneurysms with a bicuspid aortic valve. Ann. Anat., 192(3):145-50.
PMID: 20427168 -
Species: Human
Sample Types: Whole Cells
Applications: ICCKim MH et al. (2010), The effect of VEGF on the myogenic differentiation of adipose tissue derived stem cells within thermosensitive hydrogel matrices. Biomaterials, 31(6):1213-8.
PMID: 19914711 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCZhang F et al. (2010), Lysosome-dependent Ca(2+) release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts. Am. J. Physiol., Cell Physiol., 298(5):C1209-16.
PMID: 20200208 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCZhou G et al. (2009), Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1. Am. J. Physiol. Lung Cell Mol. Physiol., 297(6):L1120-30.
PMID: 19801454 -
Species: Human
Sample Types: Whole Cells
Applications: ICCEdward M et al. (2008), Gadodiamide contrast agent 'activates' fibroblasts: a possible cause of nephrogenic systemic fibrosis. J. Pathol., 214(5):584-93.
PMID: 18220317 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCHawsawi NM et al. (2008), Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes. Cancer Res., 68(8):2717-25.
PMID: 18413739 -
Species: Rabbit
Sample Types: Whole Tissue
Applications: IHCFujimoto S et al. (2008), Molecular imaging of matrix metalloproteinase in atherosclerotic lesions: resolution with dietary modification and statin therapy. J. Am. Coll. Cardiol., 52(23):1847-57.
PMID: 19038682 -
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western BlotChetty A et al. (2008), Role of matrix metalloprotease-9 in hyperoxic injury in developing lung. Am. J. Physiol. Lung Cell Mol. Physiol., 295(4):L584-92.
PMID: 18658276 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSynenki L et al. (2007), Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation. Crit. Care Med., 35(3):842-8.
PMID: 17255860 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotHong KM et al. (2007), Differentiation of human circulating fibrocytes as mediated by transforming growth factor-beta and peroxisome proliferator-activated receptor gamma. J. Biol. Chem., 282(31):22910-20.
PMID: 17556364 -
Species: Human
Sample Types: Whole Cells
Applications: ICCPan X et al. (0), Establishment and characterization of an immortalized human hepatic stellate cell line for applications in co-culturing with immortalized human hepatocytes. Int J Med Sc12(3):248-55.
PMID: 25678842
There are no citations that match your criteria.
Customer Reviews (8)
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Application: Western BlotSample Tested: Endothelial cellsSpecies: MouseVerified Customer | Posted 10/19/2021
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Application: ImmunohistochemistrySample Tested: Testicular tissueSpecies: MouseVerified Customer | Posted 08/10/2021
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Application: ImmunohistochemistrySample Tested: Muscle tissueSpecies: MouseVerified Customer | Posted 08/04/2021
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Application: ImmunohistochemistrySample Tested: Breast cancer tissueSpecies: HumanVerified Customer | Posted 02/19/2019
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Application: Western BlotSample Tested: HEK293 human embryonic kidney cell lineSpecies: HumanVerified Customer | Posted 07/21/2018
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: HMVEC human microvascular endothelial cellsSpecies: HumanVerified Customer | Posted 12/28/2017
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Application: Western BlotSample Tested: Skin tissueSpecies: MouseVerified Customer | Posted 10/20/2017
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Application: Western BlotSample Tested: Lung tissueSpecies: MouseVerified Customer | Posted 10/20/2017The antibody works well for lung tissue of mouse.
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