Histone H2AX Antibody (CL5157) [PerCP]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44279PCP
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Concentration
Product Specifications
Immunogen
Clonality
Host
Isotype
Applications for Histone H2AX Antibody (CL5157) [PerCP]
Immunocytochemistry/ Immunofluorescence
Immunohistochemistry-Paraffin
Formulation, Preparation, and Storage
Purification
Formulation
Preservative
Concentration
Shipping
Stability & Storage
Background: Histone H2AX
Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.
Alternate Names
Gene Symbol
Additional Histone H2AX Products
Product Documents for Histone H2AX Antibody (CL5157) [PerCP]
Product Specific Notices for Histone H2AX Antibody (CL5157) [PerCP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.