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3 results for "VRL1 Small Molecules and Peptides" in Products

VRL1: Small Molecules and Peptides

Caterina et al has identified a structurally related receptor, VRL-1, that does not respond to capsaicin, acid or moderate heat. Instead, VRL-1 is activated by high temperatures, with a threshold of approximately 52 degrees C. Within sensory ganglia, VRL-1 is most prominently expressed by a subset of medium- to large-diameter neurons, making it a candidate receptor for transducing high-threshold heat responses in this class of cells. VRL-1 transcripts are not restricted to the sensory nervous ...

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MRP and OAT3 inhibitor

Selective TRPV2 antagonist

Antiallergic; inhibits inflammatory mediator release from mast cells

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