Tranilast

Tocris Bioscience, part of Bio-Techne | Catalog # 1098

Antiallergic; inhibits inflammatory mediator release from mast cells
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Key Product Details

Description

Antiallergic; inhibits inflammatory mediator release from mast cells

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Product Description

Tranilast is an antiallergic via inhibition of chemical mediator release from mast cells. Shown to be an effective inhibitor of angiogenesis. Demonstrated to antagonize the effects of angiotensin II on human arteries, possibly by an interaction at the level of the AT1 receptor. Inhibits TRPV2-mediated responses; binds to Aβ40 monomers and increases Aβ40 fibrillation.

Product Specifications

Molecular Weight

327.34

Formula

C18H17NO5

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid

CAS Number

53902-12-8

PubChem ID

5282230

InChI Key

NZHGWWWHIYHZNX-CSKARUKUSA-N

SMILES

COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.73 100

Preparing Stock Solutions for Tranilast

The following data is based on the product molecular weight 327.34

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.05 mL 15.27 mL 30.55 mL
5 mM 0.61 mL 3.05 mL 6.11 mL
10 mM 0.31 mL 1.53 mL 3.05 mL
50 mM 0.06 mL 0.31 mL 0.61 mL

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Product Documents for Tranilast

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tranilast

For research use only

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