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Tripeptidyl-Peptidase I/TPP1 Products
Tripeptidyl-peptidase I (TPP1), also known as CLN2, is a lysosomal serine protease detected in all tissues examined, with highest levels shown in heart and placenta. It is an aminopeptidase that cleaves tripeptides from the free N-terminus of polypeptides and may also have endopeptidase activity. Defects in TPP1 are the cause of classical late-infantile neuronal ceroid lipofusionosis, also known as ceroid lipofusionosis neuronal 2 (CLN2), a fatal childhood neurodegenerative disease characterized by progressive visual and mental decline, motor disturbance, epilepsy, and behavioral changes.
4 results for "Tripeptidyl-Peptidase I/TPP1" in Products
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Tripeptidyl-Peptidase I/TPP1 Products
Tripeptidyl-peptidase I (TPP1), also known as CLN2, is a lysosomal serine protease detected in all tissues examined, with highest levels shown in heart and placenta. It is an aminopeptidase that cleaves tripeptides from the free N-terminus of polypeptides and may also have endopeptidase activity. Defects in TPP1 are the cause of classical late-infantile neuronal ceroid lipofusionosis, also known as ceroid lipofusionosis neuronal 2 (CLN2), a fatal childhood neurodegenerative disease characterized by progressive visual and mental decline, motor disturbance, epilepsy, and behavioral changes.
4 results for "Tripeptidyl-Peptidase I/TPP1" in Products
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #254008 |
| Applications : | Immunoprecipitation, Western Blot |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunoprecipitation, Western Blot |
| Source : | NS0 |
| Accession # : | O14773 |
| Applications : | Enzyme Activity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Western Blot |
