TRAILR1/TNFRSF10A Products
TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members.
TRAIL binds at least five different receptors: TRAILR1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAILR1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis. The remaining receptors are decoys that may regulate TRAIL activity by competing for binding sites with TRAILR1 and R2.
TRAILR3 is membrane-associated via GPI linkage. TRAILR4 is a type 1 transmembrane receptor, but exhibits a truncated cytoplasmic domain. Like the active receptors TRAILR1 and R2, OPG has a DD motif but is a soluble protein.
Products:
406 results for "TRAILR1/TNFRSF10A" in Products
406 results for "TRAILR1/TNFRSF10A" in Products
TRAILR1/TNFRSF10A Products
TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members.
TRAIL binds at least five different receptors: TRAILR1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (OPG). TRAIL receptors all exhibit cysteine-rich repeats characteristic of the TNF receptor superfamily. TRAILR1 and R2 are type 1 transmembrane proteins with intracellular death domains (DD) and, subsequently, have the ability to mediate TRAIL-induced apoptosis. The remaining receptors are decoys that may regulate TRAIL activity by competing for binding sites with TRAILR1 and R2.
TRAILR3 is membrane-associated via GPI linkage. TRAILR4 is a type 1 transmembrane receptor, but exhibits a truncated cytoplasmic domain. Like the active receptors TRAILR1 and R2, OPG has a DD motif but is a soluble protein.
Products:
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow, IHC, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #32A1380 |
| Applications: | WB, ICC/IF, Flow, CyTOF-ready, Simple Western |
![Western Blot: TRAILR1/TNFRSF10A Antibody (32A1380)BSA Free [NB100-56747]](https://resources.bio-techne.com/images/products/TRAIL-R1-TNFRSF10A-Antibody-32A1380-Western-Blot-NB100-56747-img0002.jpg "Western Blot: TRAILR1/TNFRSF10A Antibody (32A1380)BSA Free [NB100-56747]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #32A1380 |
| Applications: | WB, Flow, CyTOF-ready, B/N, Simple Western |
![Western Blot: TRAILR1/TNFRSF10A Antibody (32A1380)Azide and BSA Free [NBP2-27350]](https://resources.bio-techne.com/images/products/TRAIL-R1-TNFRSF10A-Antibody-32A1380-Azide-Free-Western-Blot-NBP2-27350-img0001.jpg "Western Blot: TRAILR1/TNFRSF10A Antibody (32A1380)Azide and BSA Free [NBP2-27350]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #32A242 |
| Applications: | WB, ICC/IF |
![Western Blot: TRAILR1/TNFRSF10A Antibody (32A242)BSA Free [NB100-56528]](https://resources.bio-techne.com/images/products/TRAIL-R1-TNFRSF10A-Antibody-32A242-Western-Blot-NB100-56528-img0003.jpg "Western Blot: TRAILR1/TNFRSF10A Antibody (32A242)BSA Free [NB100-56528]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #32A242 |
| Applications: | WB |
![Western Blot: TRAILR1/TNFRSF10A Antibody (32A242)Azide Free [NBP2-27415]](https://resources.bio-techne.com/images/products/TRAILR1-TNFRSF10A-Antibody-32A242-Azide-Free-Western-Blot-NBP2-27415-img0002.jpg "Western Blot: TRAILR1/TNFRSF10A Antibody (32A242)Azide Free [NBP2-27415]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TRAILR1/TNFRSF10A Antibody [NBP2-33716]](https://resources.bio-techne.com/images/products/TRAILR1-TNFRSF10A-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-33716-img0002.jpg "Immunocytochemistry/ Immunofluorescence: TRAILR1/TNFRSF10A Antibody [NBP2-33716]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: TRAILR1/TNFRSF10A AntibodyBSA Free [NBP2-25092]](https://resources.bio-techne.com/images/products/TRAILR1-TNFRSF10A-Antibody-Western-Blot-NBP2-25092-img0011.jpg "Western Blot: TRAILR1/TNFRSF10A AntibodyBSA Free [NBP2-25092]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #69036 |
| Applications: | Flow |