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16 results for "TR-FRET and FP Assay Reagents Fluorescent Probes and Dyes" in Products

TR-FRET and FP Assay Reagents: Fluorescent Probes and Dyes

Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation

CoraFluor 1, amine reactive product vial
(3)

High affinity cereblon fluorescent probe

Chemical Name: 2-((1E,3E)-5-((E)-1-(6-((4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
Purity: ≥90% (HPLC)
High affinity cereblon fluorescent probe

High affinity fluorescent probe for TR-FRET cereblon binding assay

Chemical Name: 3-(5,5-Difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide
Purity: ≥95% (HPLC)
High affinity fluorescent probe for TR-FRET cereblon binding assay

High-affinity VHL fluorescent probe for TR-FRET and FP assays

Chemical Name: (2S,4R)-1-((S)-2-(tert-Butyl)-21-(5,5-difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-4,19-dioxo-6,9,12,15-tetraoxa-3,18-diazahenicosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥95%
High-affinity VHL fluorescent probe for TR-FRET and FP assays

Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation

CoraFluor 2, amine reactive product vial
(3)

Terbium cryptate FRET donor for TR-FRET assay development, cysteine reactive for conjugation

CoraFluor™ 1, thiol reactive product vial

Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays

Purity: ≥95% (HPLC)
Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays

Potent fluorescent PARP inhibitor; cell permeable

Alternate Names: AZD2281-BDY FL,Olaparib-BDY FL
Chemical Name: (T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron
Purity: ≥90% (HPLC)
Potent fluorescent PARP inhibitor; cell permeable

SARS-CoV-2 main protease fluorescent ligand; TR-FRET acceptor

Purity: ≥95% (HPLC)
Fluorescence polarisation assay to determine the inhibitory activity of nirmatrelvir on purified SARS-CoV-2 Main protease protein
(2)

Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)

Chemical Name: N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
Purity: ≥90% (HPLC)
Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)

Fluorescent BET bromodomain probe; suitable for use in TR-FRET

Chemical Name: (S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate
Purity: ≥95% (HPLC)
Fluorescent BET bromodomain probe; suitable for use in TR-FRET

Fluorescent ligand for α4β1 (VLA-4)

Purity: ≥90% (HPLC)
Fluorescent ligand for α4β1 (VLA-4)

Potent and partially selective hD2 dopamine receptor fluorescent antagonist

Purity: ≥95% (HPLC)
Applications: Flow
Application of CELT-426 (100 nM) in CHO cells.
(3)

Selective hα1A adrenergic receptor fluorescent antagonist

Purity: ≥95% (HPLC)
Selective hα1A adrenergic receptor fluorescent antagonist

Fluorescent serotonin 5HT2B receptor ligand for HTS

Purity: ≥95% (HPLC)
Application of CELT-211 in CHO cells expressing the human 5HT2BR.

Potent and selective hA2B/A3 adenosine receptor fluorescent antagonist

Purity: ≥95% (HPLC)
Applications: Flow
Application of CELT-327 to live colorectal cancer cells
(2)
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