TR-FRET and FP Assay Reagents

Tocrifluor T1117

Catalog #: 2540

Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)

Chemical Name:

N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Purity:

≥90%

LDV FITC

Catalog #: 4577

Citations (10)

Product Documents

Images (1)

Fluorescent ligand for α4β1 (VLA-4)

Purity:

≥90%

PARPi-FL

Catalog #: 6461

Citations (6)

Product Documents

Images (1)

Potent fluorescent PARP inhibitor; cell permeable

Alternate Names:

AZD2281-BDY FL,Olaparib-BDY FL

Chemical Name:

(T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron

Purity:

≥90%

Thalidomide-Cyanine 5

Catalog #: 7288

Citations (93)

Product Documents

Images (1)

High affinity cereblon fluorescent probe

Chemical Name:

2-((1E,3E)-5-((E)-1-(6-((4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate

Purity:

≥90%

BDY FL VH032

Catalog #: 7483

Product Documents

Images (1)

High-affinity VHL fluorescent probe for TR-FRET and FP assays

Chemical Name:

(2S,4R)-1-((S)-2-(tert-Butyl)-21-(5,5-difluoro-7,9-dimethyl-5H-5λ⁴,6λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-4,19-dioxo-6,9,12,15-tetraoxa-3,18-diazahenicosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

Purity:

≥95%

BDY FL Thalidomide

Catalog #: 7633

Product Documents

Images (1)

High affinity fluorescent probe for TR-FRET cereblon binding assay

Chemical Name:

3-(5,5-Difluoro-7,9-dimethyl-5H-5λ⁴,6λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide

Purity:

≥95%

JQ1-FITC

Catalog #: 7722

Citations (2)

Product Documents

Images (1)

Fluorescent BET bromodomain probe; suitable for use in TR-FRET

Chemical Name:

(S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate

Purity:

≥95%

CoraFluor™ 1, amine reactive

Catalog #: 7920

Citations (6)

Product Documents

Images (3)

Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation

CoraFluor™ 2, amine reactive

Catalog #: 7950

Citations (1)

Product Documents

Images (3)

Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation

CELT-133

Catalog #: 7952

Product Documents

Images (1)

Selective hα1A adrenergic receptor fluorescent antagonist

Purity:

≥95%

CELT-211

Catalog #: 7953

Product Documents

Images (1)

Fluorescent serotonin 5HT2B receptor ligand for HTS

Purity:

≥95%

CELT-327

Catalog #: 7954

Product Documents

Images (2)

Potent and selective hA2B/A3 adenosine receptor fluorescent antagonist

Purity:

≥95%

CELT-426

Catalog #: 7955

Citations (1)

Product Documents

Images (3)

Potent and partially selective hD2 dopamine receptor fluorescent antagonist

Purity:

≥95%

BDY FL Staurosporine

Catalog #: 7985

Product Documents

Images (1)

Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays

Purity:

≥95%

CST 530, Phenol

Catalog #: 8066

Product Documents

Images (1)

Functionalized IAP ligand for PROTACs®

Chemical Name:

tert-Butyl ((S)-1-(((S)-1-cyclohexyl-2-((2S,4S)-4-(3-hydroxyphenoxy)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate

Purity:

≥95%