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TLR7 Products
TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.
19 results for "TLR7" in Products
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TLR7 Products
TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof. Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.
19 results for "TLR7" in Products
Toll-like receptor 7 (TLR7) agonist
| Alternate Names : | R 848 |
| Chemical Name : | 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol |
| Purity : | ≥98% (HPLC) |
Toll-like receptor 7 (TLR7) agonist
| Alternate Names : | R 837 |
| Chemical Name : | 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine |
| Purity : | ≥99% (HPLC) |
Potent TLR7 agonist
| Chemical Name : | Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate |
| Purity : | ≥98% (HPLC) |
Potent TLR7 agonist
| Chemical Name : | 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one |
| Purity : | ≥98% (HPLC) |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #726606 |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2a Clone #533707 |
| Applications : | Flow Cytometry |
