Tie-2: Antibodies
Tie-2, also known as Tek, is a transmembrane receptor tyrosine kinase (RTK) that functions as a receptor for Angiopoietin family proteins. It is expressed by embryonic and adult endothelial cells, hematopoietic stem cells, and a circulating population of proangiogenic monocytes. Tie-2 signaling is activated by Angiopoietins-1 and -4, while it can be either activated or inhibited by Angiopoietins-2 and -3. Tie-2 plays an important role in maintaining vascular integrity by mediating endothelial cell-smooth muscle cell communication and inhibiting endothelial cell apoptosis. It is also required for embryonic development of the endocardium. In addition, Tie-2 signaling mediates the quiescence of bone marrow stem cells in response to osteoblast-produced Angiopoietin-1. This quiescence is critical for maintaining an ongoing hematopoietic capability in the bone marrow.
22 results for "Tie-2 Primary Antibodies" in Products
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Tie-2: Antibodies
Tie-2, also known as Tek, is a transmembrane receptor tyrosine kinase (RTK) that functions as a receptor for Angiopoietin family proteins. It is expressed by embryonic and adult endothelial cells, hematopoietic stem cells, and a circulating population of proangiogenic monocytes. Tie-2 signaling is activated by Angiopoietins-1 and -4, while it can be either activated or inhibited by Angiopoietins-2 and -3. Tie-2 plays an important role in maintaining vascular integrity by mediating endothelial cell-smooth muscle cell communication and inhibiting endothelial cell apoptosis. It is also required for embryonic development of the endocardium. In addition, Tie-2 signaling mediates the quiescence of bone marrow stem cells in response to osteoblast-produced Angiopoietin-1. This quiescence is critical for maintaining an ongoing hematopoietic capability in the bone marrow.
22 results for "Tie-2 Primary Antibodies" in Products
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Simple Western, Western Blot |
Clonality : | Polyclonal |
Host : | Rabbit IgG |
Applications : | CyTOF-ready, Flow Cytometry, Immunohistochemistry, Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Rabbit IgG |
Applications : | Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83711 |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Block/Neutralize, Immunohistochemistry, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #176222 |
Applications : | Block/Neutralize, Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG2a Clone #83708 |
Applications : | ELISA Capture |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Polyclonal |
Host : | Goat IgG |
Applications : | Western Blot |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83704 |
Applications : | ELISA Detection |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |
Clonality : | Monoclonal |
Host : | Mouse IgG1 Clone #83715 |
Applications : | Flow Cytometry |