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TC-PTP Products

T cell protein tyrosine phosphatase (TC-PTP), also known as PTPT and PTPN2, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. TC-PTP dephosphorylates a wide range of phosphoproteins, such as p52Shc and receptors for EGF, Insulin and Growth Hormone. Although found in many cell types and tissues, TC-PTP is particulary prominent in hemopoietic cell types. Knockout mice lacking TC-PTP are born viable but die 3 to 5 weeks after birth of erythropoietic and lymphopoietic deficits, indicating a critical role for TC-PTP in bone marrow maturation.

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111 results for "TC-PTP" in Products

111 results for "TC-PTP" in Products

TC-PTP Products

T cell protein tyrosine phosphatase (TC-PTP), also known as PTPT and PTPN2, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. TC-PTP dephosphorylates a wide range of phosphoproteins, such as p52Shc and receptors for EGF, Insulin and Growth Hormone. Although found in many cell types and tissues, TC-PTP is particulary prominent in hemopoietic cell types. Knockout mice lacking TC-PTP are born viable but die 3 to 5 weeks after birth of erythropoietic and lymphopoietic deficits, indicating a critical role for TC-PTP in bone marrow maturation.

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Substrate for PTP1B, TC-PTP, SHP-2, and Tyrosine Phosphatase

Source: E. coli
Accession #: Q96AU5
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Western Blot: TC-PTP/PTPN2 Antibody [NBP2-48528]
(8)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunohistochemistry-Paraffin: TC-PTP/PTPN2 Antibody [NBP2-48841]
(7)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB
Western Blot: TC-PTP/PTPN2 Antibody [NBP1-60093]
(2)
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB, IP
TC-PTP/PTPN2 Antibody
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: WB
Western Blot: TC-PTP/PTPN2 Antibody [NBP1-59509]
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